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Hepatic Gi signaling regulates whole-body glucose homeostasis.
Rossi M, Zhu L, McMillin SM, Pydi SP, Jain S, Wang L, Cui Y, Lee RJ, Cohen AH, Kaneto H, Birnbaum MJ, Ma Y, Rotman Y, Liu J, Cyphert TJ, Finkel T, McGuinness OP, Wess J. Rossi M, et al. Among authors: mcguinness op. J Clin Invest. 2018 Feb 1;128(2):746-759. doi: 10.1172/JCI94505. Epub 2018 Jan 16. J Clin Invest. 2018. PMID: 29337301 Free PMC article.
Factors which regulate net hepatic glucose uptake in vivo.
Cherrington AD, Pagliassotti MJ, Myers SR, Adkins-Marshall B, McGuinness OP. Cherrington AD, et al. Among authors: mcguinness op. JPEN J Parenter Enteral Nutr. 1991 May-Jun;15(3):71S-73S. doi: 10.1177/014860719101500371S. JPEN J Parenter Enteral Nutr. 1991. PMID: 1865561 Review.
A liver Hif-2α-Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition.
Wei K, Piecewicz SM, McGinnis LM, Taniguchi CM, Wiegand SJ, Anderson K, Chan CW, Mulligan KX, Kuo D, Yuan J, Vallon M, Morton L, Lefai E, Simon MC, Maher JJ, Mithieux G, Rajas F, Annes J, McGuinness OP, Thurston G, Giaccia AJ, Kuo CJ. Wei K, et al. Among authors: mcguinness op. Nat Med. 2013 Oct;19(10):1331-1337. doi: 10.1038/nm.3295. Epub 2013 Sep 15. Nat Med. 2013. PMID: 24037094 Free PMC article.
Impact of continuous and pulsatile insulin delivery on net hepatic glucose uptake.
Grubert JM, Lautz M, Lacy DB, Moore MC, Farmer B, Penaloza A, Cherrington AD, McGuinness OP. Grubert JM, et al. Among authors: mcguinness op. Am J Physiol Endocrinol Metab. 2005 Aug;289(2):E232-40. doi: 10.1152/ajpendo.00567.2004. Epub 2005 Mar 8. Am J Physiol Endocrinol Metab. 2005. PMID: 15755768 Free article.
Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis.
Vázquez-Borrego MC, Del Río-Moreno M, Pyatkov M, Sarmento-Cabral A, Mahmood M, Pelke N, Wnek M, Cordoba-Chacon J, Waxman DJ, Puchowicz MA, McGuinness OP, Kineman RD. Vázquez-Borrego MC, et al. Among authors: mcguinness op. Metabolism. 2023 Jul;144:155589. doi: 10.1016/j.metabol.2023.155589. Epub 2023 May 13. Metabolism. 2023. PMID: 37182789 Free PMC article.
137 results