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Page 1
Visual read of [F-18]florquinitau PET that includes and extends beyond the mesial temporal lobe is associated with increased plasma pTau217 and cognitive decline in a cohort that is enriched with risk for Alzheimer's disease.
Rea Reyes RE, Cody KA, Wilson RE, Zetterberg H, Chin NA, Jonaitis EM, Bahr M, Mandel O, Wintlend M, Bendlin BB, Okonkwo OC, Clark LR, Zammit M, Asthana S, Christian BT, Betthauser TJ, Eisenmenger L, Langhough RE, Johnson SC. Rea Reyes RE, et al. Among authors: christian bt. Alzheimers Dement. 2024 Nov 19. doi: 10.1002/alz.14406. Online ahead of print. Alzheimers Dement. 2024. PMID: 39560002
Association of Age at Menopause and Hormone Therapy Use With Tau and β-Amyloid Positron Emission Tomography.
Coughlan GT, Betthauser TJ, Boyle R, Koscik RL, Klinger HM, Chibnik LB, Jonaitis EM, Yau WW, Wenzel A, Christian BT, Gleason CE, Saelzler UG, Properzi MJ, Schultz AP, Hanseeuw BJ, Manson JE, Rentz DM, Johnson KA, Sperling R, Johnson SC, Buckley RF. Coughlan GT, et al. Among authors: christian bt. JAMA Neurol. 2023 May 1;80(5):462-473. doi: 10.1001/jamaneurol.2023.0455. JAMA Neurol. 2023. PMID: 37010830 Free PMC article.
Plasma phosphorylated tau 217 in preclinical Alzheimer's disease.
Jonaitis EM, Janelidze S, Cody KA, Langhough R, Du L, Chin NA, Mattsson-Carlgren N, Hogan KJ, Christian BT, Betthauser TJ, Hansson O, Johnson SC. Jonaitis EM, et al. Among authors: christian bt. Brain Commun. 2023 Mar 6;5(2):fcad057. doi: 10.1093/braincomms/fcad057. eCollection 2023. Brain Commun. 2023. PMID: 37013174 Free PMC article.
Plasma NT1-tau and Aβ42 correlate with age and cognitive function in two large Down syndrome cohorts.
Stern AM, Van Pelt KL, Liu L, Anderson AK, Ostaszewski B, Mapstone M, O'Bryant S, Petersen ME, Christian BT, Handen BL, Selkoe DJ, Schmitt F, Head E; Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) investigators. Stern AM, et al. Among authors: christian bt. Alzheimers Dement. 2023 Dec;19(12):5755-5764. doi: 10.1002/alz.13382. Epub 2023 Jul 12. Alzheimers Dement. 2023. PMID: 37438872 Free PMC article.
AT(N) biomarker profiles and Alzheimer's disease symptomology in Down syndrome.
Hartley SL, Handen B, Tudorascu D, Lee L, Cohen A, Schworer EK, Peven JC, Zammit M, Klunk W, Laymon C, Minhas D, Luo W, Zaman S, Ances B, Preboske G, Christian BT; Alzheimer Biomarker Consortium - Down Syndrome. Hartley SL, et al. Among authors: christian bt. Alzheimers Dement. 2024 Jan;20(1):366-375. doi: 10.1002/alz.13446. Epub 2023 Aug 28. Alzheimers Dement. 2024. PMID: 37641428 Free PMC article.
Characterizing the emergence of amyloid and tau burden in Down syndrome.
Zammit MD, Betthauser TJ, McVea AK, Laymon CM, Tudorascu DL, Johnson SC, Hartley SL, Converse AK, Minhas DS, Zaman SH, Ances BM, Stone CK, Mathis CA, Cohen AD, Klunk WE, Handen BL, Christian BT; Alzheimer's Biomarker Consortium - Down Syndrome. Zammit MD, et al. Among authors: christian bt. Alzheimers Dement. 2024 Jan;20(1):388-398. doi: 10.1002/alz.13444. Epub 2023 Aug 29. Alzheimers Dement. 2024. PMID: 37641577 Free PMC article.
Harnessing cognitive trajectory clusterings to examine subclinical decline risk factors.
Du L, Hermann BP, Jonaitis EM, Cody KA, Rivera-Rivera L, Rowley H, Field A, Eisenmenger L, Christian BT, Betthauser TJ, Larget B, Chappell R, Janelidze S, Hansson O, Johnson SC, Langhough R. Du L, et al. Among authors: christian bt. Brain Commun. 2023 Dec 3;5(6):fcad333. doi: 10.1093/braincomms/fcad333. eCollection 2023. Brain Commun. 2023. PMID: 38107504 Free PMC article.
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Among authors: christian bt. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
Measurement of synaptic density in Down syndrome using PET imaging: a pilot study.
DiFilippo A, Jonaitis E, Makuch R, Gambetti B, Fleming V, Ennis G, Barnhart T, Engle J, Bendlin B, Johnson S, Handen B, Krinsky-McHale S, Hartley S, Christian B. DiFilippo A, et al. Sci Rep. 2024 Feb 26;14(1):4676. doi: 10.1038/s41598-024-54669-7. Sci Rep. 2024. PMID: 38409349 Free PMC article.
202 results