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Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies.
Tarpley M, Oladapo HO, Strepay D, Caligan TB, Chdid L, Shehata H, Roques JR, Thomas R, Laudeman CP, Onyenwoke RU, Darr DB, Williams KP. Tarpley M, et al. Eur J Pharm Sci. 2021 Jul 1;162:105821. doi: 10.1016/j.ejps.2021.105821. Epub 2021 Mar 27. Eur J Pharm Sci. 2021. PMID: 33781856 Free PMC article.
Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies.
Arora J, Sauer SJ, Tarpley M, Vermeulen P, Rypens C, Van Laere S, Williams KP, Devi GR, Dewhirst MW. Arora J, et al. Among authors: tarpley m. Oncotarget. 2017 Apr 18;8(16):25848-25863. doi: 10.18632/oncotarget.15667. Oncotarget. 2017. PMID: 28460441 Free PMC article.
62 results