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831 results

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Tumor cell-derived spermidine promotes a pro-tumorigenic immune microenvironment in glioblastoma via CD8+ T cell inhibition.
Kay KE, Lee J, Hong ES, Beilis J, Dayal S, Wesley ER, Mitchell S, Wang SZ, Silver DJ, Volovetz J, Johnson S, McGraw M, Grabowski M, Lu T, Freytag L, Narayana VK, Freytag S, Best SA, Whittle JR, Wang Z, Reizes O, Yu JS, Hazen SL, Brown JM, Bayik D, Lathia J. Kay KE, et al. Among authors: grabowski m. J Clin Invest. 2024 Nov 19:e177824. doi: 10.1172/JCI177824. Online ahead of print. J Clin Invest. 2024. PMID: 39561012 Free article.
Tumor Treating Fields: killing two birds with one stone.
Lee J, Grabowski MM, Lathia JD. Lee J, et al. Among authors: grabowski mm. J Clin Invest. 2022 Apr 15;132(8):e159073. doi: 10.1172/JCI159073. J Clin Invest. 2022. PMID: 35426370 Free PMC article.
Myeloid-Derived Suppressor Cell Subsets Drive Glioblastoma Growth in a Sex-Specific Manner.
Bayik D, Zhou Y, Park C, Hong C, Vail D, Silver DJ, Lauko A, Roversi G, Watson DC, Lo A, Alban TJ, McGraw M, Sorensen M, Grabowski MM, Otvos B, Vogelbaum MA, Horbinski C, Kristensen BW, Khalil AM, Hwang TH, Ahluwalia MS, Cheng F, Lathia JD. Bayik D, et al. Among authors: grabowski mm. Cancer Discov. 2020 Aug;10(8):1210-1225. doi: 10.1158/2159-8290.CD-19-1355. Epub 2020 Apr 16. Cancer Discov. 2020. PMID: 32300059 Free PMC article.
Distinct Cell Adhesion Signature Defines Glioblastoma Myeloid-Derived Suppressor Cell Subsets.
Bayik D, Bartels CF, Lovrenert K, Watson DC, Zhang D, Kay K, Lee J, Lauko A, Johnson S, Lo A, Silver DJ, McGraw M, Grabowski M, Mohammadi AM, Veglia F, Fan Y, Vogelbaum MA, Scacheri P, Lathia JD. Bayik D, et al. Among authors: grabowski m. Cancer Res. 2022 Nov 15;82(22):4274-4287. doi: 10.1158/0008-5472.CAN-21-3840. Cancer Res. 2022. PMID: 36126163 Free PMC article.
Sex-Biased T-cell Exhaustion Drives Differential Immune Responses in Glioblastoma.
Lee J, Nicosia M, Hong ES, Silver DJ, Li C, Bayik D, Watson DC, Lauko A, Kay KE, Wang SZ, Johnson S, McGraw M, Grabowski MM, Kish DD, Desai AB, Goodman WA, Cameron SJ, Okada H, Valujskikh A, Fairchild RL, Ahluwalia MS, Lathia JD. Lee J, et al. Among authors: grabowski mm. Cancer Discov. 2023 Sep 6;13(9):2090-2105. doi: 10.1158/2159-8290.CD-22-0869. Cancer Discov. 2023. PMID: 37378557 Free PMC article.
Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis.
Alban TJ, Alvarado AG, Sorensen MD, Bayik D, Volovetz J, Serbinowski E, Mulkearns-Hubert EE, Sinyuk M, Hale JS, Onzi GR, McGraw M, Huang P, Grabowski MM, Wathen CA, Ahluwalia MS, Radivoyevitch T, Kornblum HI, Kristensen BW, Vogelbaum MA, Lathia JD. Alban TJ, et al. Among authors: grabowski mm. JCI Insight. 2018 Nov 2;3(21):e122264. doi: 10.1172/jci.insight.122264. JCI Insight. 2018. PMID: 30385717 Free PMC article.
Metronomic capecitabine as an immune modulator in glioblastoma patients reduces myeloid-derived suppressor cells.
Peereboom DM, Alban TJ, Grabowski MM, Alvarado AG, Otvos B, Bayik D, Roversi G, McGraw M, Huang P, Mohammadi AM, Kornblum HI, Radivoyevitch T, Ahluwalia MS, Vogelbaum MA, Lathia JD. Peereboom DM, et al. Among authors: grabowski mm. JCI Insight. 2019 Nov 14;4(22):e130748. doi: 10.1172/jci.insight.130748. JCI Insight. 2019. PMID: 31600167 Free PMC article. Clinical Trial.
Preclinical Modeling of Surgery and Steroid Therapy for Glioblastoma Reveals Changes in Immunophenotype that are Associated with Tumor Growth and Outcome.
Otvos B, Alban TJ, Grabowski MM, Bayik D, Mulkearns-Hubert EE, Radivoyevitch T, Rabljenovic A, Johnson S, Androjna C, Mohammadi AM, Barnett GH, Ahluwalia MS, Vogelbaum MA, Fecci PE, Lathia JD. Otvos B, et al. Among authors: grabowski mm. Clin Cancer Res. 2021 Apr 1;27(7):2038-2049. doi: 10.1158/1078-0432.CCR-20-3262. Epub 2021 Feb 4. Clin Cancer Res. 2021. PMID: 33542075 Free PMC article.
The MIF promoter SNP rs755622 is associated with immune activation in glioblastoma.
Alban TJ, Grabowski MM, Otvos B, Bayik D, Wang W, Zalavadia A, Makarov V, Troike K, McGraw M, Rabljenovic A, Lauko A, Neumann C, Roversi G, Waite KA, Cioffi G, Patil N, Tran TT, McCortney K, Steffens A, Diaz CM, Brown JM, Egan KM, Horbinski CM, Barnholtz-Sloan JS, Rajappa P, Vogelbaum MA, Bucala R, Chan TA, Ahluwalia MS, Lathia JD. Alban TJ, et al. Among authors: grabowski mm. JCI Insight. 2023 Jul 10;8(13):e160024. doi: 10.1172/jci.insight.160024. JCI Insight. 2023. PMID: 37252795 Free PMC article.
831 results