Zhang S - Search Results

1

Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors.

Sui Q, Zhou Y, Li M, Wang D, Cui R, Cai X, Liu J, Wang X, Teng D, Zhou J, Hou H, Zhang S, Zheng M. Sui Q, et al. Among authors: zhang s. Eur J Med Chem. 2025 Jan 15;282:117039. doi: 10.1016/j.ejmech.2024.117039. Epub 2024 Nov 12. Eur J Med Chem. 2025. PMID: 39561494

2

Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor.

Wang K, Zhou Z, Ma X, Xu J, Xu W, Zhou G, Zhou C, Li H, Zheng M, Zhang S, Xu T. Wang K, et al. Among authors: zhang s. Bioorg Med Chem Lett. 2024 Jul 15;107:129780. doi: 10.1016/j.bmcl.2024.129780. Epub 2024 May 5. Bioorg Med Chem Lett. 2024. PMID: 38714262

3

Targeting STING oligomerization with licochalcone D ameliorates STING-driven inflammatory diseases.

Zhang Y, Liu Y, Jiang B, Chen L, Hu J, Niu B, Chang J, Fan Z, Zhou J, Wang Y, Teng D, Ma N, Wang X, Yang R, Zheng M, Zhang S. Zhang Y, et al. Among authors: zhang s. Sci China Life Sci. 2024 Dec;67(12):2664-2677. doi: 10.1007/s11427-024-2703-6. Epub 2024 Aug 22. Sci China Life Sci. 2024. PMID: 39190126

4

KinomeMETA: meta-learning enhanced kinome-wide polypharmacology profiling.

Ren Q, Qu N, Sun J, Zhou J, Liu J, Ni L, Tong X, Zhang Z, Kong X, Wen Y, Wang Y, Wang D, Luo X, Zhang S, Zheng M, Li X. Ren Q, et al. Among authors: zhang s, zhang z. Brief Bioinform. 2023 Nov 22;25(1):bbad461. doi: 10.1093/bib/bbad461. Brief Bioinform. 2023. PMID: 38113075 Free PMC article.

5

An updated patent review of SOS1 inhibitors (2022-present).

Zhou G, Zhou C, Ma X, Xu J, Zhou Z, Xu T, Zheng M, Zhang S. Zhou G, et al. Among authors: zhang s. Expert Opin Ther Pat. 2024 Dec;34(12):1199-1213. doi: 10.1080/13543776.2024.2419825. Epub 2024 Oct 25. Expert Opin Ther Pat. 2024. PMID: 39435474 Review.

6

KinomeMETA: a web platform for kinome-wide polypharmacology profiling with meta-learning.

Li Z, Qu N, Zhou J, Sun J, Ren Q, Meng J, Wang G, Wang R, Liu J, Chen Y, Zhang S, Zheng M, Li X. Li Z, et al. Among authors: zhang s. Nucleic Acids Res. 2024 Jul 5;52(W1):W489-W497. doi: 10.1093/nar/gkae380. Nucleic Acids Res. 2024. PMID: 38752486 Free PMC article.

7

Identifying compound-protein interactions with knowledge graph embedding of perturbation transcriptomics.

Ni S, Kong X, Zhang Y, Chen Z, Wang Z, Fu Z, Huo R, Tong X, Qu N, Wu X, Wang K, Zhang W, Zhang R, Zhang Z, Shi J, Wang Y, Yang R, Li X, Zhang S, Zheng M. Ni S, et al. Among authors: zhang r, zhang s, zhang w, zhang z, zhang y. Cell Genom. 2024 Oct 9;4(10):100655. doi: 10.1016/j.xgen.2024.100655. Epub 2024 Sep 19. Cell Genom. 2024. PMID: 39303708 Free PMC article.

8

MolFilterGAN: a progressively augmented generative adversarial network for triaging AI-designed molecules.

Liu X, Zhang W, Tong X, Zhong F, Li Z, Xiong Z, Xiong J, Wu X, Fu Z, Tan X, Liu Z, Zhang S, Jiang H, Li X, Zheng M. Liu X, et al. Among authors: zhang s, zhang w. J Cheminform. 2023 Apr 8;15(1):42. doi: 10.1186/s13321-023-00711-1. J Cheminform. 2023. PMID: 37031191 Free PMC article.

9

The therapeutic effect of a novel GAPDH inhibitor in mouse model of breast cancer and efficacy monitoring by molecular imaging.

Zhang YQ, Zhang W, Kong XT, Hai WX, Guo R, Zhang M, Zhang SL, Li B. Zhang YQ, et al. Cancer Cell Int. 2024 May 29;24(1):188. doi: 10.1186/s12935-024-03361-x. Cancer Cell Int. 2024. PMID: 38811918 Free PMC article.

10

G-quadruplex structures and their interaction diversity with ligands.

Zhang S, Wu Y, Zhang W. Zhang S, et al. Among authors: zhang w. ChemMedChem. 2014 May;9(5):899-911. doi: 10.1002/cmdc.201300566. Epub 2014 Apr 11. ChemMedChem. 2014. PMID: 24729465 Review.

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