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Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling.
Brumm AS, McCarthy A, Gerri C, Fallesen T, Woods L, McMahon R, Papathanasiou A, Elder K, Snell P, Christie L, Garcia P, Shaikly V, Taranissi M, Serhal P, Odia RA, Vasilic M, Osnato A, Rugg-Gunn PJ, Vallier L, Hill CS, Niakan KK. Brumm AS, et al. Among authors: vallier l. Dev Cell. 2025 Jan 20;60(2):174-185.e5. doi: 10.1016/j.devcel.2024.10.020. Epub 2024 Nov 18. Dev Cell. 2025. PMID: 39561779 Free article.
Genome editing reveals a role for OCT4 in human embryogenesis.
Fogarty NME, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, Lea R, Elder K, Wamaitha SE, Kim D, Maciulyte V, Kleinjung J, Kim JS, Wells D, Vallier L, Bertero A, Turner JMA, Niakan KK. Fogarty NME, et al. Among authors: vallier l. Nature. 2017 Oct 5;550(7674):67-73. doi: 10.1038/nature24033. Epub 2017 Sep 20. Nature. 2017. PMID: 28953884 Free PMC article.
Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation.
Ortmann D, Brown S, Czechanski A, Aydin S, Muraro D, Huang Y, Tomaz RA, Osnato A, Canu G, Wesley BT, Skelly DA, Stegle O, Choi T, Churchill GA, Baker CL, Rugg-Gunn PJ, Munger SC, Reinholdt LG, Vallier L. Ortmann D, et al. Among authors: vallier l. Cell Stem Cell. 2020 Sep 3;27(3):470-481.e6. doi: 10.1016/j.stem.2020.07.019. Epub 2020 Aug 13. Cell Stem Cell. 2020. PMID: 32795399 Free PMC article.
Derivation of pluripotent epiblast stem cells from mammalian embryos.
Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, Chuva de Sousa Lopes SM, Howlett SK, Clarkson A, Ahrlund-Richter L, Pedersen RA, Vallier L. Brons IG, et al. Among authors: vallier l. Nature. 2007 Jul 12;448(7150):191-5. doi: 10.1038/nature05950. Epub 2007 Jun 27. Nature. 2007. PMID: 17597762
Method to Synchronize Cell Cycle of Human Pluripotent Stem Cells without Affecting Their Fundamental Characteristics.
Yiangou L, Grandy RA, Morell CM, Tomaz RA, Osnato A, Kadiwala J, Muraro D, Garcia-Bernardo J, Nakanoh S, Bernard WG, Ortmann D, McCarthy DJ, Simonic I, Sinha S, Vallier L. Yiangou L, et al. Among authors: vallier l. Stem Cell Reports. 2019 Jan 8;12(1):165-179. doi: 10.1016/j.stemcr.2018.11.020. Epub 2018 Dec 27. Stem Cell Reports. 2019. PMID: 30595546 Free PMC article.
188 results