Feng Y - Search Results

1

Lysine-Targeted Covalent Inhibitors of PI3Kδ Synthesis and Screening by In Situ Interaction Upgradation.

Yuan B, Feng Y, Ma M, Duan W, Wu Y, Liu J, Zhao HY, Yang Z, Zhang SQ, Xin M. Yuan B, et al. Among authors: feng y. J Med Chem. 2024 Nov 28;67(22):20076-20099. doi: 10.1021/acs.jmedchem.4c01284. Epub 2024 Nov 19. J Med Chem. 2024. PMID: 39561981

2

Novel 6-aryl substituted 4-pyrrolidineaminoquinazoline derivatives as potent phosphoinositide 3-kinase delta (PI3Kδ) inhibitors.

Xin M, Duan W, Feng Y, Hei YY, Zhang H, Shen Y, Zhao HY, Mao S, Zhang SQ. Xin M, et al. Among authors: feng y. Bioorg Med Chem. 2018 May 1;26(8):2028-2040. doi: 10.1016/j.bmc.2018.03.002. Epub 2018 Mar 2. Bioorg Med Chem. 2018. PMID: 29534936

3

Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors.

Xin M, Duan W, Feng Y, Hei YY, Zhang H, Shen Y, Zhao HY, Mao S, Zhang SQ. Xin M, et al. Among authors: feng y. J Enzyme Inhib Med Chem. 2018 Dec;33(1):651-656. doi: 10.1080/14756366.2018.1444608. J Enzyme Inhib Med Chem. 2018. PMID: 29536777 Free PMC article.

4

Alkylsulfonamide-containing quinazoline derivatives as potent and orally bioavailable PI3Ks inhibitors.

Hei YY, Zhang SQ, Feng Y, Wang J, Duan W, Zhang H, Mao S, Sun H, Xin M. Hei YY, et al. Among authors: feng y. Bioorg Med Chem. 2019 Oct 15;27(20):114930. doi: 10.1016/j.bmc.2019.05.043. Epub 2019 May 31. Bioorg Med Chem. 2019. PMID: 31176568

5

Synthesis and biological evaluation of 4-(piperid-3-yl)amino substituted 6-pyridylquinazolines as potent PI3Kδ inhibitors.

Feng Y, Duan W, Fan S, Zhang H, Zhang SQ, Xin M. Feng Y, et al. Bioorg Med Chem. 2019 Oct 1;27(19):115035. doi: 10.1016/j.bmc.2019.07.051. Epub 2019 Jul 31. Bioorg Med Chem. 2019. PMID: 31434616

6

PI3Kδ inhibitors for the treatment of cancer: a patent review (2015-present).

Feng Y, Cu X, Xin M. Feng Y, et al. Expert Opin Ther Pat. 2019 Dec;29(12):925-941. doi: 10.1080/13543776.2019.1687685. Epub 2019 Nov 7. Expert Opin Ther Pat. 2019. PMID: 31670985 Review.

7

Research advances on selective phosphatidylinositol 3 kinase δ (PI3Kδ) inhibitors.

Sun J, Feng Y, Huang Y, Zhang SQ, Xin M. Sun J, et al. Among authors: feng y. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127457. doi: 10.1016/j.bmcl.2020.127457. Epub 2020 Aug 2. Bioorg Med Chem Lett. 2020. PMID: 32755681 Review.

8

Discovery of potent and selective PI3Kδ inhibitors bearing amino acid fragments.

Lei H, Duan W, Zhang SQ, Feng Y, Ma M, Yuan B, Xin M. Lei H, et al. Among authors: feng y. Bioorg Chem. 2023 Sep;138:106594. doi: 10.1016/j.bioorg.2023.106594. Epub 2023 May 8. Bioorg Chem. 2023. PMID: 37186998

9

Design, synthesis and biological evaluation of novel selective PI3Kδ inhibitors containing pyridopyrimidine scaffold.

Ma M, Feng Y, Zhang SQ, Duan W, Gao L, Yuan B, Xin M. Ma M, et al. Among authors: feng y. Future Med Chem. 2023 Aug;15(16):1491-1509. doi: 10.4155/fmc-2023-0149. Epub 2023 Aug 11. Future Med Chem. 2023. PMID: 37565336

10

Bruton's tyrosine kinase (BTK) inhibitors in treating cancer: a patent review (2010-2018).

Feng Y, Duan W, Cu X, Liang C, Xin M. Feng Y, et al. Expert Opin Ther Pat. 2019 Apr;29(4):217-241. doi: 10.1080/13543776.2019.1594777. Expert Opin Ther Pat. 2019. PMID: 30888232 Review.

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