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C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line.
Zoch A, Konieczny G, Auchynnikava T, Stallmeyer B, Rotte N, Heep M, Berrens RV, Schito M, Kabayama Y, Schöpp T, Kliesch S, Houston B, Nagirnaja L, O'Bryan MK, Aston KI, Conrad DF, Rappsilber J, Allshire RC, Cook AG, Tüttelmann F, O'Carroll D. Zoch A, et al. Mol Cell. 2024 Mar 21;84(6):1021-1035.e11. doi: 10.1016/j.molcel.2024.01.014. Epub 2024 Feb 14. Mol Cell. 2024. PMID: 38359823 Free article.
A time- and single-cell-resolved model of murine bone marrow hematopoiesis.
Kucinski I, Campos J, Barile M, Severi F, Bohin N, Moreira PN, Allen L, Lawson H, Haltalli MLR, Kinston SJ, O'Carroll D, Kranc KR, Göttgens B. Kucinski I, et al. Cell Stem Cell. 2024 Feb 1;31(2):244-259.e10. doi: 10.1016/j.stem.2023.12.001. Epub 2024 Jan 5. Cell Stem Cell. 2024. PMID: 38183977 Free PMC article.
The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia.
Lawson H, Holt-Martyn JP, Dembitz V, Kabayama Y, Wang LM, Bellani A, Atwal S, Saffoon N, Durko J, van de Lagemaat LN, De Pace AL, Tumber A, Corner T, Salah E, Arndt C, Brewitz L, Bowen M, Dubusse L, George D, Allen L, Guitart AV, Fung TK, So CWE, Schwaller J, Gallipoli P, O'Carroll D, Schofield CJ, Kranc KR. Lawson H, et al. Nat Cancer. 2024 Jun;5(6):916-937. doi: 10.1038/s43018-024-00761-w. Epub 2024 Apr 18. Nat Cancer. 2024. PMID: 38637657 Free PMC article.
Two-factor authentication underpins the precision of the piRNA pathway.
Dias Mirandela M, Zoch A, Leismann J, Webb S, Berrens RV, Valsakumar D, Kabayama Y, Auchynnikava T, Schito M, Chowdhury T, MacLeod D, Xiang X, Zou J, Rappsilber J, Allshire RC, Voigt P, Cook AG, Barau J, O'Carroll D. Dias Mirandela M, et al. Among authors: o carroll d. Nature. 2024 Oct;634(8035):979-985. doi: 10.1038/s41586-024-07963-3. Epub 2024 Sep 18. Nature. 2024. PMID: 39294378 Free PMC article.
280 results