Sprando RL - Search Results

1

In Vitro Biological Target Screening and Colloidal Aggregation of Minor Cannabinoids.

Santillo MF, Glenn IS, Paris L, Sprando RL. Santillo MF, et al. Among authors: sprando rl. J Nat Prod. 2024 Dec 27;87(12):2881-2886. doi: 10.1021/acs.jnatprod.4c00608. Epub 2024 Nov 19. J Nat Prod. 2024. PMID: 39563095

2

Predicting binding between 55 cannabinoids and 4,799 biological targets by in silico methods.

Santillo MF, Sprando RL. Santillo MF, et al. Among authors: sprando rl. J Appl Toxicol. 2023 Oct;43(10):1476-1487. doi: 10.1002/jat.4478. Epub 2023 May 10. J Appl Toxicol. 2023. PMID: 37101313

3

Picamilon, a γ-aminobutyric acid (GABA) analogue and marketed nootropic, is inactive against 50 biological targets.

Santillo MF, Sprando RL. Santillo MF, et al. Among authors: sprando rl. Basic Clin Pharmacol Toxicol. 2023 Apr;132(4):355-358. doi: 10.1111/bcpt.13836. Epub 2023 Jan 31. Basic Clin Pharmacol Toxicol. 2023. PMID: 36668678 Free article.

4

Physiologically based pharmacokinetic modeling and simulation of cannabinoids in human plasma and tissues.

Liu Y, Sprando RL. Liu Y, et al. Among authors: sprando rl. J Appl Toxicol. 2023 Apr;43(4):589-598. doi: 10.1002/jat.4409. Epub 2022 Nov 3. J Appl Toxicol. 2023. PMID: 36272108

5

Anthraquinones inhibit cytochromes P450 enzyme activity in silico and in vitro.

Liu Y, Mapa MST, Sprando RL. Liu Y, et al. Among authors: sprando rl. J Appl Toxicol. 2021 Sep;41(9):1438-1445. doi: 10.1002/jat.4134. Epub 2021 Jan 12. J Appl Toxicol. 2021. PMID: 33438235

6

Examining the hepatotoxic potential of cannabidiol, cannabidiol-containing hemp extract, and cannabinol at consumer-relevant exposure concentrations in primary human hepatocytes.

Striz A, Zhao Y, Sepehr E, Vaught C, Eckstrum K, Headrick K, Yourick J, Sprando R. Striz A, et al. J Appl Toxicol. 2024 Oct;44(10):1595-1605. doi: 10.1002/jat.4646. Epub 2024 Jun 26. J Appl Toxicol. 2024. PMID: 38924151

7

Comparison on the mechanism and potency of hepatotoxicity among hemp extract and its four major constituent cannabinoids.

Gao X, Campasino K, Yourick MR, Zhao Y, Sepehr E, Vaught C, Sprando RL, Yourick JJ. Gao X, et al. Among authors: sprando rl. Toxicology. 2024 Aug;506:153885. doi: 10.1016/j.tox.2024.153885. Epub 2024 Jul 14. Toxicology. 2024. PMID: 39004335 Free article.

8

Strengths and limitations of the worm development and activity test (wDAT) as a chemical screening tool for developmental hazards.

Hunt PR, Welch B, Camacho J, Salazar JK, Fay ML, Hamm J, Ceger P, Allen D, Fitzpatrick SC, Yourick J, Sprando RL. Hunt PR, et al. Among authors: sprando rl. Toxicol Appl Pharmacol. 2024 Nov;492:117108. doi: 10.1016/j.taap.2024.117108. Epub 2024 Sep 23. Toxicol Appl Pharmacol. 2024. PMID: 39322068 Free article.

9

Comparative cytotoxicity of nanosilver in human liver HepG2 and colon Caco2 cells in culture.

Sahu SC, Zheng J, Graham L, Chen L, Ihrie J, Yourick JJ, Sprando RL. Sahu SC, et al. Among authors: sprando rl. J Appl Toxicol. 2014 Nov;34(11):1155-66. doi: 10.1002/jat.2994. Epub 2014 Feb 12. J Appl Toxicol. 2014. PMID: 24522958

10

Development and validation of a fit-for-purpose UHPLC-ESI-MS/MS method for the quantitation of cannabinoids in different matrices.

Zhao Y, Sepehr E, Vaught C, Yourick J, Sprando RL. Zhao Y, et al. Among authors: sprando rl. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Mar 1;1218:123629. doi: 10.1016/j.jchromb.2023.123629. Epub 2023 Feb 21. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 36854205

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