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Page 1
Design and Synthesis of 2-Nitroimidazole-1,2,3-triazole Sulfonamide Hybrids as Potent and Selective Anti-Trypanosomatid Agents.
Tietz VC, Ortale MLF, das Neves AR, Pelizaro BI, Carvalho DB, Shiguemoto CYK, Portapilla GB, Silva TS, Silva F, Piranda EM, Leite CR, Dantas FGS, Oliveira KMP, Guerrero PG Jr, Marques FA, LaGatta DC, Arruda CCP, de Albuquerque S, Baroni ACM. Tietz VC, et al. Among authors: das neves ar. ChemMedChem. 2024 Nov 20:e202400516. doi: 10.1002/cmdc.202400516. Online ahead of print. ChemMedChem. 2024. PMID: 39565682
Design and Synthesis of Novel 3-Nitro-1H-1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis.
Pelizaro BI, Batista JCZ, Portapilla GB, das Neves AR, Silva F, Carvalho DB, Shiguemoto CYK, Pessatto LR, Paredes-Gamero EJ, Cardoso IA, Luccas PH, Nonato MC, Lopes NP, Galvão F, Oliveira KMP, Cassemiro NS, Silva DB, Piranda EM, Arruda CCP, de Albuquerque S, Baroni ACM. Pelizaro BI, et al. Among authors: das neves ar. J Med Chem. 2024 Feb 22;67(4):2584-2601. doi: 10.1021/acs.jmedchem.3c01745. Epub 2024 Feb 2. J Med Chem. 2024. PMID: 38305199
Antileishmanial Activity, Toxicity and Mechanism of Action of Complexes of Sodium Usnate with Lanthanide Ions: Eu(III), Sm(III), Gd(III), Nd(III), La(III) and Tb(III).
da Silva F, Rizk YS, das Neves AR, Lourenço EMG, Ferreira AMT, Monteiro MM, de Lima DP, Perdomo RT, Bonfá IS, Toffoli-Kadri MC, Duarte AP, Nunes DM, Martines MAU, Piranda EM, de Arruda CCP. da Silva F, et al. Among authors: das neves ar. Int J Mol Sci. 2023 Dec 28;25(1):413. doi: 10.3390/ijms25010413. Int J Mol Sci. 2023. PMID: 38203584 Free PMC article.
Neuroprotective Profile of Triazole Grandisin Analogue against Amyloid-Beta Oligomer-Induced Cognitive Impairment.
Andrade VHB, M Rodrigues EY, Dias NAF, Ferreira GFC, Carvalho DB, das Neves AR, Coronel PMV, Yonekawa MKA, Parisotto EB, Santos EAD, Souza AS, Paredes-Gamero EJ, de Sousa KS, Souza LL, Resstel LBM, Baroni ACM, Lagatta DC. Andrade VHB, et al. Among authors: das neves ar. ACS Chem Neurosci. 2023 Dec 20;14(24):4298-4310. doi: 10.1021/acschemneuro.3c00443. Epub 2023 Dec 4. ACS Chem Neurosci. 2023. PMID: 38048522
Investigation of the Potential Targets behind the Promising and Highly Selective Antileishmanial Action of Synthetic Flavonoid Derivatives.
Lourenço EMG, da Silva F, das Neves AR, Bonfá IS, Ferreira AMT, Menezes ACG, da Silva MEC, Dos Santos JT, Martines MAU, Perdomo RT, Toffoli-Kadri MC, G Barbosa E, Saba S, Beatriz A, Rafique J, de Arruda CCP, de Lima DP. Lourenço EMG, et al. Among authors: das neves ar. ACS Infect Dis. 2023 Oct 13;9(10):2048-2061. doi: 10.1021/acsinfecdis.3c00336. Epub 2023 Sep 29. ACS Infect Dis. 2023. PMID: 37772925
Design, synthesis and antitrypanosomatid activity of 2-nitroimidazole-3,5-disubstituted isoxazole compounds based on benznidazole.
Carvalho DB, Costa PAN, Portapilla GB, das Neves AR, Shiguemoto CYK, Pelizaro BI, Silva F, Piranda EM, Arruda CCP, Gaspari PDM, Cardoso IA, Luccas PH, Nonato MC, Lopes NP, de Albuquerque S, Baroni ACM. Carvalho DB, et al. Among authors: das neves ar. Eur J Med Chem. 2023 Nov 15;260:115451. doi: 10.1016/j.ejmech.2023.115451. Epub 2023 May 5. Eur J Med Chem. 2023. PMID: 37573209
In Vivo Antileishmanial Effect of 3,5-Diaryl-isoxazole Analogues Based on Veraguensin, Grandisin, and Machilin G: A Glance at a Preclinical Study.
das Neves AR, Carvalho DB, Silva F, Rosalem RF, Pelizaro BI, Castilho PF, Oliveira KMP, Cassemiro NS, Pessatto LR, Paredes-Gamero EJ, Piranda EM, Silva DB, Arruda CCP, Baroni ACM. das Neves AR, et al. ACS Infect Dis. 2023 May 12;9(5):1150-1159. doi: 10.1021/acsinfecdis.3c00090. Epub 2023 Apr 27. ACS Infect Dis. 2023. PMID: 37103973
Repurposing of 5-nitrofuran-3,5-disubstituted isoxazoles: A thriving scaffold to antitrypanosomal agents.
Carvalho DB, das Neves AR, Portapilla GB, Soares O, Santos LBB, Oliveira JRS, Vianna LS, Judice WAS, Cardoso IA, Luccas PH, Nonato MC, Lopes NP, de Albuquerque S, Baroni ACM. Carvalho DB, et al. Among authors: das neves ar. Arch Pharm (Weinheim). 2023 Apr;356(4):e2200472. doi: 10.1002/ardp.202200472. Epub 2022 Dec 19. Arch Pharm (Weinheim). 2023. PMID: 36534890
15 results