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Page 1
Molecular adaptation to neoadjuvant immunotherapy in triple-negative breast cancer.
Denkert C, Schneeweiss A, Rey J, Karn T, Hattesohl A, Weber KE, Rachakonda S, Braun M, Huober J, Jank P, Sinn HP, Zahm DM, Felder B, Hanusch C, Teply-Szymanski J, Marmé F, Fehm T, Thomalla J, Sinn BV, Stiewe T, Marczyk M, Blohmer JU, van Mackelenbergh M, Schem C, Staib P, Link T, Müller V, Stickeler E, Stover DG, Solbach C, Metzger-Filho O, Jackisch C, Geyer CE Jr, Fasching PA, Pusztai L, Nekljudova V, Untch M, Loibl S. Denkert C, et al. Among authors: stiewe t. Cell Rep Med. 2024 Nov 19;5(11):101825. doi: 10.1016/j.xcrm.2024.101825. Cell Rep Med. 2024. PMID: 39566464 Free PMC article. Clinical Trial.
Arachidonic acid impairs natural killer cell functions by disrupting signaling pathways driven by activating receptors and reactive oxygen species.
Hammoud MK, Meena C, Dietze R, Hoffmann N, Szymanski W, Finkernagel F, Nist A, Stiewe T, Graumann J, von Strandmann EP, Müller R. Hammoud MK, et al. Among authors: stiewe t. Cell Commun Signal. 2024 Nov 19;22(1):555. doi: 10.1186/s12964-024-01940-z. Cell Commun Signal. 2024. PMID: 39563446 Free PMC article.
TP53: the unluckiest of genes?
Joerger AC, Stiewe T, Soussi T. Joerger AC, et al. Among authors: stiewe t. Cell Death Differ. 2024 Oct 23. doi: 10.1038/s41418-024-01391-6. Online ahead of print. Cell Death Differ. 2024. PMID: 39443700 Review.
Haptoglobin buffers lipopolysaccharides to delay activation of NFκB.
Zein L, Grossmann J, Swoboda H, Borgel C, Wilke B, Awe S, Nist A, Stiewe T, Stehling O, Freibert SA, Adhikary T, Chung HR. Zein L, et al. Among authors: stiewe t. Front Immunol. 2024 Oct 2;15:1401527. doi: 10.3389/fimmu.2024.1401527. eCollection 2024. Front Immunol. 2024. PMID: 39416789 Free PMC article.
Distinct negative-sense RNA viruses induce a common set of transcripts encoding proteins forming an extensive network.
Hofmann N, Bartkuhn M, Becker S, Biedenkopf N, Böttcher-Friebertshäuser E, Brinkrolf K, Dietzel E, Fehling SK, Goesmann A, Heindl MR, Hoffmann S, Karl N, Maisner A, Mostafa A, Kornecki L, Müller-Kräuter H, Müller-Ruttloff C, Nist A, Pleschka S, Sauerhering L, Stiewe T, Strecker T, Wilhelm J, Wuerth JD, Ziebuhr J, Weber F, Schmitz ML. Hofmann N, et al. Among authors: stiewe t. J Virol. 2024 Oct 22;98(10):e0093524. doi: 10.1128/jvi.00935-24. Epub 2024 Sep 16. J Virol. 2024. PMID: 39283124 Free PMC article.
Transcriptomic response of prostate cancer cells to carbon ion and photon irradiation with focus on androgen receptor and TP53 signaling.
Hänze J, Mengen LM, Mernberger M, Tiwari DK, Plagge T, Nist A, Subtil FSB, Theiss U, Eberle F, Roth K, Lauth M, Hofmann R, Engenhart-Cabillic R, Stiewe T, Hegele A. Hänze J, et al. Among authors: stiewe t. Radiat Oncol. 2024 Jul 2;19(1):85. doi: 10.1186/s13014-024-02480-z. Radiat Oncol. 2024. PMID: 38956684 Free PMC article.
BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells.
Alashkar Alhamwe B, Ponath V, Alhamdan F, Dörsam B, Landwehr C, Linder M, Pauck K, Miethe S, Garn H, Finkernagel F, Brichkina A, Lauth M, Tiwari DK, Buchholz M, Bachurski D, Elmshäuser S, Nist A, Stiewe T, Pogge von Strandmann L, Szymański W, Beutgen V, Graumann J, Teply-Szymanski J, Keber C, Denkert C, Jacob R, Preußer C, Pogge von Strandmann E. Alashkar Alhamwe B, et al. Among authors: stiewe t. Cell Mol Immunol. 2024 Aug;21(8):918-931. doi: 10.1038/s41423-024-01195-1. Epub 2024 Jun 28. Cell Mol Immunol. 2024. PMID: 38942797 Free PMC article.
KRAS and TP53 co-mutation predicts benefit of immune checkpoint blockade in lung adenocarcinoma.
Budczies J, Romanovsky E, Kirchner M, Neumann O, Blasi M, Schnorbach J, Shah R, Bozorgmehr F, Savai R, Stiewe T, Peters S, Schirmacher P, Thomas M, Kazdal D, Christopoulos P, Stenzinger A. Budczies J, et al. Among authors: stiewe t. Br J Cancer. 2024 Aug;131(3):524-533. doi: 10.1038/s41416-024-02746-z. Epub 2024 Jun 12. Br J Cancer. 2024. PMID: 38866964 Free PMC article.
DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer.
Brichkina A, Ems M, Suezov R, Singh R, Lutz V, Picard FSR, Nist A, Stiewe T, Graumann J, Daude M, Diederich WE, Finkernagel F, Chung HR, Bartsch DK, Roth K, Keber C, Denkert C, Huber M, Gress TM, Lauth M. Brichkina A, et al. Among authors: stiewe t. Gut. 2024 Sep 9;73(10):1684-1701. doi: 10.1136/gutjnl-2023-331854. Gut. 2024. PMID: 38834297 Free PMC article.
162 results