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Zdhhc1 deficiency mitigates foam cell formation and atherosclerosis by inhibiting PI3K-Akt-mTOR signaling pathway through facilitating the nuclear translocation of p110α.
Zhou B, Liu Y, Ma H, Zhang B, Lu B, Li S, Liu T, Qi Y, Wang Y, Zhang M, Qiu J, Fu R, Li W, Lu L, Tian S, Liu Q, Gu Y, Huang R, Lawrence T, Kong E, Zhang L, Li T, Liang Y. Zhou B, et al. Among authors: lawrence t. Biochim Biophys Acta Mol Basis Dis. 2025 Feb;1871(2):167577. doi: 10.1016/j.bbadis.2024.167577. Epub 2024 Nov 19. Biochim Biophys Acta Mol Basis Dis. 2025. PMID: 39566590
LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer.
Anstee JE, Feehan KT, Opzoomer JW, Dean I, Muller HP, Bahri M, Cheung TS, Liakath-Ali K, Liu Z, Choy D, Caron J, Sosnowska D, Beatson R, Muliaditan T, An Z, Gillett CE, Lan G, Zou X, Watt FM, Ng T, Burchell JM, Kordasti S, Withers DR, Lawrence T, Arnold JN. Anstee JE, et al. Among authors: lawrence t. Dev Cell. 2023 Sep 11;58(17):1548-1561.e10. doi: 10.1016/j.devcel.2023.06.006. Epub 2023 Jul 12. Dev Cell. 2023. PMID: 37442140 Free article.
Meningeal macrophages protect against viral neuroinfection.
Rebejac J, Eme-Scolan E, Arnaud Paroutaud L, Kharbouche S, Teleman M, Spinelli L, Gallo E, Roussel-Queval A, Zarubica A, Sansoni A, Bardin Q, Hoest P, Michallet MC, Brousse C, Crozat K, Manglani M, Liu Z, Ginhoux F, McGavern DB, Dalod M, Malissen B, Lawrence T, Rua R. Rebejac J, et al. Among authors: lawrence t. Immunity. 2022 Nov 8;55(11):2103-2117.e10. doi: 10.1016/j.immuni.2022.10.005. Epub 2022 Nov 1. Immunity. 2022. PMID: 36323311 Free article.
National Beef Quality Audit-2022: Harvest-floor assessments of hide defects, carcass defects, and offal condemnations that affect value of carcasses and by-products from market cows and bulls.
Borders SE, Schwartz TE, Mayer TR, Gehring KB, Griffin DB, Kerth CR, Belk KE, Edwards-Callaway L, Scanga JA, Nair MN, Morgan JB, Douglas JB, Pfeiffer MM, Mafi GG, Harr KM, Lawrence TE, Tennant TC, Lucherk LW, O'Quinn TG, Beyer ES, Bass PD, Garcia LG, Bohrer BM, Pempek JA, Garmyn AJ, Maddock RJ, Carr CC, Pringle TD, Scheffler TL, Scheffler JM, Stelzleni AM, Gonzalez JM, Underwood KR, Harsh BN, Waters CM, Savell JW. Borders SE, et al. Among authors: lawrence te. Transl Anim Sci. 2024 Dec 20;9:txae178. doi: 10.1093/tas/txae178. eCollection 2025. Transl Anim Sci. 2024. PMID: 39780849 Free PMC article.
Metagenomics reveals spatial variation in cyanobacterial composition, function, and biosynthetic potential in the Winam Gulf, Lake Victoria, Kenya.
Hart LN, Zepernick BN, Natwora KE, Brown KM, Obuya JA, Lomeo D, Barnard MA, Okech EO; 2022-23 NSF-IRES Lake Victoria Research Consortium; Kiledal EA, Den Uyl PA, Olokotum M, Wilhelm SW, McKay RM, Drouillard KG, Sherman DH, Sitoki L, Achiya J, Getabu A, Otiso KM, Bullerjahn GS, Dick GJ. Hart LN, et al. Appl Environ Microbiol. 2025 Jan 8:e0150724. doi: 10.1128/aem.01507-24. Online ahead of print. Appl Environ Microbiol. 2025. PMID: 39772868
Olaparib and Radiotherapy Induce Type I Interferon- and CD8+ T Cell-Dependent Sensitization to Immunotherapy in Pancreatic Cancer.
Valvo VM, Zhang Q, Jiang L, Holcomb EA, Pearson AN, Edmunds AG, Faulkner HG, James JG, Tate A, Huber AK, Wang Z, Guo Y, Karnak D, Parsels LA, Parsels JD, Lei YL, Rehemtulla A, Lin H, Carpenter ES, Wahl DR, Sahai V, Lawrence TS, Green MD, Morgan MA. Valvo VM, et al. Among authors: lawrence ts. Mol Cancer Ther. 2024 Dec 17:OF1-OF16. doi: 10.1158/1535-7163.MCT-24-0210. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39688341
Reciprocal links between methionine metabolism, DNA repair and therapy resistance in glioblastoma.
Korimerla N, Meghdadi B, Haq I, Wilder-Romans K, Xu J, Becker N, Zhu Z, Kalev P, Qi N, Evans C, Kachman M, Zhao Z, Lin A, Scott AJ, O'Brien A, Kothari A, Sajjakulnukit P, Zhang L, Palavalasa S, Peterson ER, Hyer ML, Marjon K, Sleger T, Morgan MA, Lyssiotis CA, Stone EM, Ferris SP, Lawrence TS, Nagrath D, Zhou W, Wahl DR. Korimerla N, et al. Among authors: lawrence ts. bioRxiv [Preprint]. 2024 Nov 21:2024.11.20.624542. doi: 10.1101/2024.11.20.624542. bioRxiv. 2024. PMID: 39651281 Free PMC article. Preprint.
Molecular investigation of harmful cyanobacteria reveals hidden risks and niche partitioning in Kenyan Lakes.
Zepernick BN, Hart LN, Chase EE, Natwora KE, Obuya JA, Olokotum M, Houghton KA, Kiledal EA; NSF-IRES 2022 Lake Victoria Research Consortium; Sheik CS, Sherman DH, Dick GJ, Wilhelm SW, Sitoki L, Otiso KM, McKay RML, Bullerjahn GS. Zepernick BN, et al. Harmful Algae. 2024 Dec;140:102757. doi: 10.1016/j.hal.2024.102757. Epub 2024 Nov 10. Harmful Algae. 2024. PMID: 39613370 Free PMC article.
1,088 results