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Page 1
Immunosuppressant therapy averts rejection of allogeneic FKBP1A-disrupted CAR-T cells.
Maldini CR, Messana AC, Bendet PB, Camblin AJ, Musenge FM, White ML, Rocha JJ, Coholan LJ, Karaca C, Li F, Yan B, Vrbanac VD, Marte E, Claiborne DT, Boutwell CL, Allen TM. Maldini CR, et al. Among authors: claiborne dt. Mol Ther. 2024 Oct 2;32(10):3485-3503. doi: 10.1016/j.ymthe.2024.06.022. Epub 2024 Sep 1. Mol Ther. 2024. PMID: 39222637 Free PMC article.
Intraperitoneal activation of myeloid cells clears ascites and reveals IL27-dependent regression of metastatic ovarian cancer.
Murphy B, Miyamoto T, Manning BS, Mirji G, Ugolini A, Kannan T, Hamada K, Zhu YP, Claiborne DT, Huang L, Zhang R, Nefedova Y, Kossenkov A, Veglia F, Shinde R, Zhang N. Murphy B, et al. Among authors: claiborne dt. bioRxiv [Preprint]. 2024 Jun 29:2024.06.25.600597. doi: 10.1101/2024.06.25.600597. bioRxiv. 2024. Update in: J Exp Med. 2024 Dec 2;221(12):e20231967. doi: 10.1084/jem.20231967 PMID: 38979222 Free PMC article. Updated. Preprint.
Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer.
Miller KD, O'Connor S, Pniewski KA, Kannan T, Acosta R, Mirji G, Papp S, Hulse M, Mukha D, Hlavaty SI, Salcido KN, Bertolazzi F, Srikanth YVV, Zhao S, Wellen KE, Shinde RS, Claiborne DT, Kossenkov A, Salvino JM, Schug ZT. Miller KD, et al. Among authors: claiborne dt. Nat Cancer. 2023 Oct;4(10):1491-1507. doi: 10.1038/s43018-023-00636-6. Epub 2023 Sep 18. Nat Cancer. 2023. PMID: 37723305 Free PMC article.
The African-centric P47S Variant of TP53 Confers Immune Dysregulation and Impaired Response to Immune Checkpoint Inhibition.
Stieg DC, Parris JLD, Yang THL, Mirji G, Reiser SK, Murali N, Werts M, Barnoud T, Lu DY, Shinde R, Murphy ME, Claiborne DT. Stieg DC, et al. Among authors: claiborne dt. Cancer Res Commun. 2023 Jul 11;3(7):1200-1211. doi: 10.1158/2767-9764.CRC-23-0149. eCollection 2023 Jul. Cancer Res Commun. 2023. PMID: 37441266 Free PMC article.
An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Indeglia A, Leung JC, Miller SA, Leu JI, Dougherty JF, Clarke NL, Kirven NA, Shao C, Ke L, Lovell S, Barnoud T, Lu DY, Lin C, Kannan T, Battaile KP, Yang THL, Batista Oliva I, Claiborne DT, Vogel P, Liu L, Liu Q, Nefedova Y, Cassel J, Auslander N, Kossenkov AV, Karanicolas J, Murphy ME. Indeglia A, et al. Among authors: claiborne dt. Cancer Discov. 2023 Jul 7;13(7):1696-1719. doi: 10.1158/2159-8290.CD-22-1315. Cancer Discov. 2023. PMID: 37140445 Free PMC article.
Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis.
Zhou W, Liu H, Yuan Z, Zundell J, Towers M, Lin J, Lombardi S, Nie H, Murphy B, Yang T, Wang C, Liao L, Goldman AR, Kannan T, Kossenkov AV, Drapkin R, Montaner LJ, Claiborne DT, Zhang N, Wu S, Zhang R. Zhou W, et al. Among authors: claiborne dt. Cancer Cell. 2023 Apr 10;41(4):740-756.e10. doi: 10.1016/j.ccell.2023.03.002. Epub 2023 Mar 23. Cancer Cell. 2023. PMID: 36963401 Free PMC article.
Of mice, or men: TLR4 signaling in HIV pathogenesis.
Acosta R, Claiborne DT. Acosta R, et al. Among authors: claiborne dt. J Leukoc Biol. 2023 May 2;113(5):415-417. doi: 10.1093/jleuko/qiad017. J Leukoc Biol. 2023. PMID: 36808429 No abstract available.
28 results