Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

287 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation.
Saller BS, Wöhrle S, Fischer L, Dufossez C, Ingerl IL, Kessler S, Mateo-Tortola M, Gorka O, Lange F, Cheng Y, Neuwirt E, Marada A, Koentges C, Urban C, Aktories P, Reuther P, Giese S, Kirschnek S, Mayer C, Pilic J, Falquez-Medina H, Oelgeklaus A, Deepagan VG, Shojaee F, Zimmermann JA, Weber D, Tai YH, Crois A, Ciminski K, Peyronnet R, Brandenburg KS, Wu G, Baumeister R, Heimbucher T, Rizzi M, Riedel D, Helmstädter M, Buescher J, Neumann K, Misgeld T, Kerschensteiner M, Walentek P, Kreutz C, Maurer U, Rambold AS, Vince JE, Edlich F, Malli R, Häcker G, Kierdorf K, Meisinger C, Köttgen A, Jakobs S, Weber ANR, Schwemmle M, Groß CJ, Groß O. Saller BS, et al. Among authors: gross o. Immunity. 2025 Jan 14;58(1):90-107.e11. doi: 10.1016/j.immuni.2024.10.012. Epub 2024 Nov 20. Immunity. 2025. PMID: 39571574 Free article.
PKA Has the Gall to Oppose NLRP3.
Groß CJ, Groß O. Groß CJ, et al. Among authors: gross o. Immunity. 2016 Oct 18;45(4):707-709. doi: 10.1016/j.immuni.2016.09.019. Immunity. 2016. PMID: 27760332 Free article. Review.
The Nlrp3 inflammasome admits defeat.
Groß CJ, Groß O. Groß CJ, et al. Among authors: gross o. Trends Immunol. 2015 Jun;36(6):323-4. doi: 10.1016/j.it.2015.05.001. Epub 2015 May 16. Trends Immunol. 2015. PMID: 25991463
Walking over the inflammasome.
Gorka O, Neuwirt E, Groß O. Gorka O, et al. Among authors: gross o. Nat Chem Biol. 2019 Jun;15(6):552-553. doi: 10.1038/s41589-019-0292-8. Nat Chem Biol. 2019. PMID: 31086328 No abstract available.
NLRP3 as a sensor of metabolism gone awry.
Neuwirt E, Gorka O, Saller BS, Groß CJ, Madl T, Groß O. Neuwirt E, et al. Among authors: gross cj, gross o. Curr Opin Biotechnol. 2021 Apr;68:300-309. doi: 10.1016/j.copbio.2021.03.009. Epub 2021 Apr 13. Curr Opin Biotechnol. 2021. PMID: 33862489 Review.
Tyrosine kinase inhibitors can activate the NLRP3 inflammasome in myeloid cells through lysosomal damage and cell lysis.
Neuwirt E, Magnani G, Ćiković T, Wöhrle S, Fischer L, Kostina A, Flemming S, Fischenich NJ, Saller BS, Gorka O, Renner S, Agarinis C, Parker CN, Boettcher A, Farady CJ, Kesselring R, Berlin C, Backofen R, Rodriguez-Franco M, Kreutz C, Prinz M, Tholen M, Reinheckel T, Ott T, Groß CJ, Jost PJ, Groß O. Neuwirt E, et al. Among authors: gross cj, gross o. Sci Signal. 2023 Jan 17;16(768):eabh1083. doi: 10.1126/scisignal.abh1083. Epub 2023 Jan 17. Sci Signal. 2023. PMID: 36649377
K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria.
Groß CJ, Mishra R, Schneider KS, Médard G, Wettmarshausen J, Dittlein DC, Shi H, Gorka O, Koenig PA, Fromm S, Magnani G, Ćiković T, Hartjes L, Smollich J, Robertson AAB, Cooper MA, Schmidt-Supprian M, Schuster M, Schroder K, Broz P, Traidl-Hoffmann C, Beutler B, Kuster B, Ruland J, Schneider S, Perocchi F, Groß O. Groß CJ, et al. Among authors: gross o. Immunity. 2016 Oct 18;45(4):761-773. doi: 10.1016/j.immuni.2016.08.010. Epub 2016 Sep 27. Immunity. 2016. PMID: 27692612 Free article.
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
Vince JE, Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, Mason K, Gross O, Ma S, Guarda G, Anderton H, Castillo R, Häcker G, Silke J, Tschopp J. Vince JE, et al. Among authors: o reilly l, gross o. Immunity. 2012 Feb 24;36(2):215-27. doi: 10.1016/j.immuni.2012.01.012. Immunity. 2012. PMID: 22365665 Free article.
The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.
Schneider KS, Groß CJ, Dreier RF, Saller BS, Mishra R, Gorka O, Heilig R, Meunier E, Dick MS, Ćiković T, Sodenkamp J, Médard G, Naumann R, Ruland J, Kuster B, Broz P, Groß O. Schneider KS, et al. Among authors: gross cj, gross o. Cell Rep. 2017 Dec 26;21(13):3846-3859. doi: 10.1016/j.celrep.2017.12.018. Cell Rep. 2017. PMID: 29281832 Free PMC article.
Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade.
Roth S, Cao J, Singh V, Tiedt S, Hundeshagen G, Li T, Boehme JD, Chauhan D, Zhu J, Ricci A, Gorka O, Asare Y, Yang J, Lopez MS, Rehberg M, Bruder D, Zhang S, Groß O, Dichgans M, Hornung V, Liesz A. Roth S, et al. Among authors: gross o. Immunity. 2021 Apr 13;54(4):648-659.e8. doi: 10.1016/j.immuni.2021.02.004. Epub 2021 Mar 4. Immunity. 2021. PMID: 33667383 Free article.
287 results