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Page 1
Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Fowler SL, Behr TS, Turkes E, O'Brien DP, Cauhy PM, Rawlinson I, Edmonds M, Foiani MS, Schaler A, Crowley G, Bez S, Ficulle E, Tsefou E, Fischer R, Geary B, Gaur P, Miller C, D'Acunzo P, Levy E, Duff KE, Ryskeldi-Falcon B. Fowler SL, et al. Among authors: o brien dp. Nat Neurosci. 2025 Jan;28(1):40-48. doi: 10.1038/s41593-024-01801-5. Epub 2024 Nov 21. Nat Neurosci. 2025. PMID: 39572740 Free PMC article.
Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.
Fowler SL, Behr TS, Turkes E, Cauhy PM, Foiani MS, Schaler A, Crowley G, Bez S, Ficulle E, Tsefou E, O'Brien DP, Fischer R, Geary B, Gaur P, Miller C, D'Acunzo P, Levy E, Duff KE, Ryskeldi-Falcon B. Fowler SL, et al. bioRxiv [Preprint]. 2023 Apr 30:2023.04.30.537820. doi: 10.1101/2023.04.30.537820. bioRxiv. 2023. Update in: Nat Neurosci. 2025 Jan;28(1):40-48. doi: 10.1038/s41593-024-01801-5 PMID: 37163117 Free PMC article. Updated. Preprint.
Integrative multi-omics profiling in human decedents receiving pig heart xenografts.
Schmauch E, Piening B, Mohebnasab M, Xia B, Zhu C, Stern J, Zhang W, Dowdell AK, Kim JI, Andrijevic D, Khalil K, Jaffe IS, Loza BL, Gragert L, Camellato BR, Oliveira MF, O'Brien DP, Chen HM, Weldon E, Gao H, Gandla D, Chang A, Bhatt R, Gao S, Lin X, Reddy KP, Kagermazova L, Habara AH, Widawsky S, Liang FX, Sall J, Loupy A, Heguy A, Taylor SEB, Zhu Y, Michael B, Jiang L, Jian R, Chong AS, Fairchild RL, Linna-Kuosmanen S, Kaikkonen MU, Tatapudi V, Lorber M, Ayares D, Mangiola M, Narula N, Moazami N, Pass H, Herati RS, Griesemer A, Kellis M, Snyder MP, Montgomery RA, Boeke JD, Keating BJ. Schmauch E, et al. Among authors: o brien dp. Nat Med. 2024 May;30(5):1448-1460. doi: 10.1038/s41591-024-02972-1. Epub 2024 May 17. Nat Med. 2024. PMID: 38760586
Deep Proteomics Network and Machine Learning Analysis of Human Cerebrospinal Fluid in Japanese Encephalitis Virus Infection.
Bharucha T, Gangadharan B, Kumar A, Myall AC, Ayhan N, Pastorino B, Chanthongthip A, Vongsouvath M, Mayxay M, Sengvilaipaseuth O, Phonemixay O, Rattanavong S, O'Brien DP, Vendrell I, Fischer R, Kessler B, Turtle L, de Lamballerie X, Dubot-Pérès A, Newton PN, Zitzmann N, SEAe Consortium. Bharucha T, et al. J Proteome Res. 2023 Jun 2;22(6):1614-1629. doi: 10.1021/acs.jproteome.2c00563. Epub 2023 May 23. J Proteome Res. 2023. PMID: 37219084 Free PMC article.
Tau depletion in human neurons mitigates Aβ-driven toxicity.
Ng B, Vowles J, Bertherat F, Abey A, Kilfeather P, Beccano-Kelly D, Stefana MI, O'Brien DP, Bengoa-Vergniory N, Carling PJ, Todd JA, Caffrey TM, Connor-Robson N, Cowley SA, Wade-Martins R. Ng B, et al. Mol Psychiatry. 2024 Jul;29(7):2009-2020. doi: 10.1038/s41380-024-02463-2. Epub 2024 Feb 15. Mol Psychiatry. 2024. PMID: 38361127 Free PMC article.
Quantitative proteomics reveals CLR interactome in primary human cells.
Manolis D, Hasan S, Maraveyas A, O'Brien DP, Kessler BM, Kramer H, Nikitenko LL. Manolis D, et al. Among authors: o brien dp. J Biol Chem. 2024 Jun;300(6):107399. doi: 10.1016/j.jbc.2024.107399. Epub 2024 May 20. J Biol Chem. 2024. PMID: 38777147 Free PMC article.
Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.
Ellis MJ, Lekka C, Holden KL, Tulmin H, Seedat F, O'Brien DP, Dhayal S, Zeissler ML, Knudsen JG, Kessler BM, Morgan NG, Todd JA, Richardson SJ, Stefana MI. Ellis MJ, et al. Among authors: o brien dp. Acta Neuropathol. 2024 May 18;147(1):87. doi: 10.1007/s00401-024-02729-7. Acta Neuropathol. 2024. PMID: 38761203 Free PMC article.
Deubiquitinases in muscle physiology and disorders.
Olie CS, O'Brien DP, Jones HBL, Liang Z, Damianou A, Sur-Erdem I, Pinto-Fernández A, Raz V, Kessler BM. Olie CS, et al. Among authors: o brien dp. Biochem Soc Trans. 2024 Jun 26;52(3):1085-1098. doi: 10.1042/BST20230562. Biochem Soc Trans. 2024. PMID: 38716888 Free PMC article. Review.
378 results