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Metabolic Syndrome Nonalcoholic Steatohepatitis Male Mouse With Adeno-Associated Viral Renin as a Novel Model for Heart Failure With Preserved Ejection Fraction.
Shi Y, Perez-Bonilla P, Chen X, Tam K, Marshall M, Morin J, LaViolette B, Kue NR, Damilano F, Miller RA, Zhang BB, Roth Flach RJ, Hirenallur-Shanthappa D. Shi Y, et al. J Am Heart Assoc. 2024 Dec 3;13(23):e035894. doi: 10.1161/JAHA.124.035894. Epub 2024 Nov 22. J Am Heart Assoc. 2024. PMID: 39575718 Free PMC article.
Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models.
Esquejo RM, Salatto CT, Delmore J, Albuquerque B, Reyes A, Shi Y, Moccia R, Cokorinos E, Peloquin M, Monetti M, Barricklow J, Bollinger E, Smith BK, Day EA, Nguyen C, Geoghegan KF, Kreeger JM, Opsahl A, Ward J, Kalgutkar AS, Tess D, Butler L, Shirai N, Osborne TF, Steinberg GR, Birnbaum MJ, Cameron KO, Miller RA. Esquejo RM, et al. Among authors: shi y. EBioMedicine. 2018 May;31:122-132. doi: 10.1016/j.ebiom.2018.04.009. Epub 2018 Apr 8. EBioMedicine. 2018. PMID: 29673898 Free PMC article.
Targeting hepatic glutaminase activity to ameliorate hyperglycemia.
Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ. Miller RA, et al. Among authors: shi y. Nat Med. 2018 May;24(4):518-524. doi: 10.1038/nm.4514. Epub 2018 Mar 26. Nat Med. 2018. PMID: 29578539 Free PMC article.
Malate initiates a proton-sensing pathway essential for pH regulation of inflammation.
Chen YJ, Shi RC, Xiang YC, Fan L, Tang H, He G, Zhou M, Feng XZ, Tan JD, Huang P, Ye X, Zhao K, Fu WY, Li LL, Bian XT, Chen H, Wang F, Wang T, Zhang CK, Zhou BH, Chen W, Liang TT, Lv JT, Kang X, Shi YX, Kim E, Qin YH, Hettinghouse A, Wang KD, Zhao XL, Yang MY, Tang YZ, Piao HL, Guo L, Liu CJ, Miao HM, Tang KL. Chen YJ, et al. Among authors: shi yx. Signal Transduct Target Ther. 2024 Dec 30;9(1):367. doi: 10.1038/s41392-024-02076-9. Signal Transduct Target Ther. 2024. PMID: 39737965
Research progress of novel anti-tumor drug formulations.
Liu Y, Guo Q, Shi Y, Cui M, Jing F. Liu Y, et al. Among authors: shi y. Front Oncol. 2024 Dec 16;14:1507958. doi: 10.3389/fonc.2024.1507958. eCollection 2024. Front Oncol. 2024. PMID: 39737395 Free PMC article. Review.
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