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Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations.
Hołubowicz R, Du SW, Felgner J, Smidak R, Choi EH, Palczewska G, Menezes CR, Dong Z, Gao F, Medani O, Yan AL, Hołubowicz MW, Chen PZ, Bassetto M, Risaliti E, Salom D, Workman JN, Kiser PD, Foik AT, Lyon DC, Newby GA, Liu DR, Felgner PL, Palczewski K. Hołubowicz R, et al. Among authors: felgner j. Nat Biomed Eng. 2025 Jan;9(1):57-78. doi: 10.1038/s41551-024-01296-2. Epub 2024 Nov 28. Nat Biomed Eng. 2025. PMID: 39609561 Free PMC article.
Engineering Protein Nanoparticles Functionalized with an Immunodominant Coxiella burnetii Antigen to Generate a Q Fever Vaccine.
Ramirez A, Felgner J, Jain A, Jan S, Albin TJ, Badten AJ, Gregory AE, Nakajima R, Jasinskas A, Felgner PL, Burkhardt AM, Davies DH, Wang SW. Ramirez A, et al. Among authors: felgner j. Bioconjug Chem. 2023 Sep 20;34(9):1653-1666. doi: 10.1021/acs.bioconjchem.3c00317. Epub 2023 Sep 8. Bioconjug Chem. 2023. PMID: 37682243 Free PMC article.
Evaluation of Four Adjuvant Combinations, IVAX-1, IVAX-2, CpG-1826+Montanide ISA 720 VG and CpG-1018+Montanide ISA 720 VG, for Safety and for Their Ability to Elicit Protective Immune Responses in Mice against a Respiratory Challenge with Chlamydia muridarum.
Pal S, Slepenkin A, Felgner J, Huw Davies D, Felgner P, de la Maza LM. Pal S, et al. Among authors: felgner j. Pathogens. 2023 Jun 22;12(7):863. doi: 10.3390/pathogens12070863. Pathogens. 2023. PMID: 37513710 Free PMC article.
Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants.
Hernandez-Davies JE, Dollinger EP, Pone EJ, Felgner J, Liang L, Strohmeier S, Jan S, Albin TJ, Jain A, Nakajima R, Jasinskas A, Krammer F, Esser-Kahn A, Felgner PL, Nie Q, Davies DH. Hernandez-Davies JE, et al. Among authors: felgner j. Sci Rep. 2022 Jun 2;12(1):9198. doi: 10.1038/s41598-022-12727-y. Sci Rep. 2022. PMID: 35654904 Free PMC article.
49 results