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Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches.
Abba Moussa D, Vazquez M, Chable-Bessia C, Roux-Portalez V, Tamagnini E, Pedotti M, Simonelli L, Ngo G, Souchard M, Lyonnais S, Chentouf M, Gros N, Marsile-Medun S, Dinter H, Pugnière M, Martineau P, Varani L, Juan M, Calderon H, Naranjo-Gomez M, Pelegrin M. Abba Moussa D, et al. Among authors: simonelli l. Emerg Microbes Infect. 2025 Dec;14(1):2432345. doi: 10.1080/22221751.2024.2432345. Epub 2024 Dec 9. Emerg Microbes Infect. 2025. PMID: 39584380 Free PMC article.
Adapting Neutralizing Antibodies to Viral Variants by Structure-Guided Affinity Maturation Using Phage Display Technology.
Peissert F, Pedotti M, Corbellari R, Simonelli L, De Gasparo R, Tamagnini E, Plüss L, Elsayed A, Matasci M, De Luca R, Cassaniti I, Sammartino JC, Piralla A, Baldanti F, Neri D, Varani L. Peissert F, et al. Among authors: simonelli l. Glob Chall. 2023 Aug 21;7(10):2300088. doi: 10.1002/gch2.202300088. eCollection 2023 Oct. Glob Chall. 2023. PMID: 37829677 Free PMC article.
A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity.
Bardelli M, Frontzek K, Simonelli L, Hornemann S, Pedotti M, Mazzola F, Carta M, Eckhardt V, D'Antuono R, Virgilio T, González SF, Aguzzi A, Varani L. Bardelli M, et al. Among authors: simonelli l. PLoS Pathog. 2018 Oct 1;14(10):e1007335. doi: 10.1371/journal.ppat.1007335. eCollection 2018 Oct. PLoS Pathog. 2018. PMID: 30273408 Free PMC article.
Epitope mapping by solution NMR spectroscopy.
Bardelli M, Livoti E, Simonelli L, Pedotti M, Moraes A, Valente AP, Varani L. Bardelli M, et al. Among authors: simonelli l. J Mol Recognit. 2015 Jun;28(6):393-400. doi: 10.1002/jmr.2454. Epub 2015 Feb 27. J Mol Recognit. 2015. PMID: 25726811
183 results