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141 results

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Page 1
Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts.
Zein JG, Zounemat-Kerman N, Adcock IM, Hu B, Attaway A, Castro M, Dahlén SE, Denlinger LC, Erzurum SC, Fahy JV, Gaston B, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Moore W, Peters MC, Sumino K, Townsend E, Woodruff P, Ortega VE, Wenzel SE, Meyers DA, Chung KF, Bleecker ER; Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) Consortium and the the US National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP III). Zein JG, et al. Among authors: hastie at. Lancet Respir Med. 2025 Jan;13(1):35-46. doi: 10.1016/S2213-2600(24)00250-9. Epub 2024 Nov 22. Lancet Respir Med. 2025. PMID: 39586307
Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency.
Peters MC, Mauger D, Ross KR, Phillips B, Gaston B, Cardet JC, Israel E, Levy BD, Phipatanakul W, Jarjour NN, Castro M, Wenzel SE, Hastie A, Moore W, Bleecker E, Fahy JV, Denlinger LC. Peters MC, et al. Am J Respir Crit Care Med. 2020 Oct 1;202(7):973-982. doi: 10.1164/rccm.201909-1813OC. Am J Respir Crit Care Med. 2020. PMID: 32479111 Free PMC article.
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program.
Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, D'Agostino R Jr, Castro M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Moore WC, et al. Am J Respir Crit Care Med. 2010 Feb 15;181(4):315-23. doi: 10.1164/rccm.200906-0896OC. Epub 2009 Nov 5. Am J Respir Crit Care Med. 2010. PMID: 19892860 Free PMC article.
Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program.
Jarjour NN, Erzurum SC, Bleecker ER, Calhoun WJ, Castro M, Comhair SA, Chung KF, Curran-Everett D, Dweik RA, Fain SB, Fitzpatrick AM, Gaston BM, Israel E, Hastie A, Hoffman EA, Holguin F, Levy BD, Meyers DA, Moore WC, Peters SP, Sorkness RL, Teague WG, Wenzel SE, Busse WW; NHLBI Severe Asthma Research Program (SARP). Jarjour NN, et al. Am J Respir Crit Care Med. 2012 Feb 15;185(4):356-62. doi: 10.1164/rccm.201107-1317PP. Epub 2011 Nov 17. Am J Respir Crit Care Med. 2012. PMID: 22095547 Free PMC article.
Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.
Han MK, Quibrera PM, Carretta EE, Barr RG, Bleecker ER, Bowler RP, Cooper CB, Comellas A, Couper DJ, Curtis JL, Criner G, Dransfield MT, Hansel NN, Hoffman EA, Kanner RE, Krishnan JA, Martinez CH, Pirozzi CB, O'Neal WK, Rennard S, Tashkin DP, Wedzicha JA, Woodruff P, Paine R 3rd, Martinez FJ; SPIROMICS investigators. Han MK, et al. Lancet Respir Med. 2017 Aug;5(8):619-626. doi: 10.1016/S2213-2600(17)30207-2. Epub 2017 Jun 28. Lancet Respir Med. 2017. PMID: 28668356 Free PMC article.
Estimated Ventricular Size, Asthma Severity, and Exacerbations: The Severe Asthma Research Program III Cohort.
Ash SY, Sanchez-Ferrero GV, Schiebler ML, Rahaghi FN, Rai A, Come CE, Ross JC, Colon AG, Cardet JC, Bleecker ER, Castro M, Fahy JV, Fain SB, Gaston BM, Hoffman EA, Jarjour NN, Lempel JK, Mauger DT, Tattersall MC, Wenzel SE, Levy BD, Washko GR, Israel E, San Jose Estepar R; SARP Investigators. Ash SY, et al. Chest. 2020 Feb;157(2):258-267. doi: 10.1016/j.chest.2019.08.2185. Epub 2019 Sep 12. Chest. 2020. PMID: 31521672 Free PMC article.
Quantitative CT Characteristics of Cluster Phenotypes in the Severe Asthma Research Program Cohorts.
Trivedi AP, Hall C, Goss CW, Lew D, Krings JG, McGregor MC, Samant M, Sieren JP, Li H, Schechtman KB, Schirm J, McEleney S, Peterson S, Moore WC, Bleecker ER, Meyers DA, Israel E, Washko GR, Levy BD, Leader JK, Wenzel SE, Fahy JV, Schiebler ML, Fain SB, Jarjour NN, Mauger DT, Reinhardt JM, Newell JD Jr, Hoffman EA, Castro M, Sheshadri A; NHLBI Severe Asthma Research Program (SARP). Trivedi AP, et al. Radiology. 2022 Aug;304(2):450-459. doi: 10.1148/radiol.210363. Epub 2022 Apr 26. Radiology. 2022. PMID: 35471111 Free PMC article.
Bronchial epithelial cell transcriptional responses to inhaled corticosteroids dictate severe asthmatic outcomes.
Ginebaugh SP, Hagner M, Ray A, Erzurum SC, Comhair SAA, Denlinger LC, Jarjour NN, Castro M, Woodruff PG, Christenson SA, Bleecker ER, Meyers DA, Hastie AT, Moore WC, Mauger DT, Israel E, Levy BD, Wenzel SE, Camiolo MJ. Ginebaugh SP, et al. Among authors: hastie at. J Allergy Clin Immunol. 2023 Jun;151(6):1513-1524. doi: 10.1016/j.jaci.2023.01.028. Epub 2023 Feb 14. J Allergy Clin Immunol. 2023. PMID: 36796454 Free PMC article.
CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma.
Gauthier M, Kale SL, Oriss TB, Gorry M, Ramonell RP, Dalton K, Ray P, Fahy JV, Seibold MA, Castro M, Jarjour N, Gaston B, Bleecker ER, Meyers DA, Moore W, Hastie AT, Israel E, Levy BD, Mauger D, Erzurum S, Comhair SA, Wenzel SE, Ray A. Gauthier M, et al. Among authors: hastie at. J Allergy Clin Immunol. 2023 Jul;152(1):94-106.e12. doi: 10.1016/j.jaci.2023.02.028. Epub 2023 Mar 8. J Allergy Clin Immunol. 2023. PMID: 36893862 Free PMC article.
Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma.
Huang BK, Elicker BM, Henry TS, Kallianos KG, Hahn LD, Tang M, Heng F, McCulloch CE, Bhakta NR, Majumdar S, Choi J, Denlinger LC, Fain SB, Hastie AT, Hoffman EA, Israel E, Jarjour NN, Levy BD, Mauger DT, Sumino K, Wenzel SE, Castro M, Woodruff PG, Fahy JV, Sarp FTNSARP. Huang BK, et al. Among authors: hastie at. JCI Insight. 2024 Feb 8;9(3):e174124. doi: 10.1172/jci.insight.174124. JCI Insight. 2024. PMID: 38127464 Free PMC article.
141 results