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DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways.
Chopra S, Kadiri OL, Ulke J, Hauffe R, Jonas W, Cheshmeh S, Schmidt L, Bishop CA, Yagoub S, Schell M, Rath M, Krüger J, Lippert RN, Krüger M, Kappert K, Kleinridders A. Chopra S, et al. Among authors: schell m. Cell Rep. 2024 Nov 25;43(12):114984. doi: 10.1016/j.celrep.2024.114984. Online ahead of print. Cell Rep. 2024. PMID: 39589923 Free article.
GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity.
Hauffe R, Stein V, Chudoba C, Flore T, Rath M, Ritter K, Schell M, Wardelmann K, Deubel S, Kopp JF, Schwarz M, Kappert K, Blüher M, Schwerdtle T, Kipp AP, Kleinridders A. Hauffe R, et al. Among authors: schell m. JCI Insight. 2020 Jun 4;5(11):e136283. doi: 10.1172/jci.insight.136283. JCI Insight. 2020. PMID: 32369454 Free PMC article.
Central Acting Hsp10 Regulates Mitochondrial Function, Fatty Acid Metabolism, and Insulin Sensitivity in the Hypothalamus.
Wardelmann K, Rath M, Castro JP, Blümel S, Schell M, Hauffe R, Schumacher F, Flore T, Ritter K, Wernitz A, Hosoi T, Ozawa K, Kleuser B, Weiß J, Schürmann A, Kleinridders A. Wardelmann K, et al. Among authors: schell m. Antioxidants (Basel). 2021 Apr 30;10(5):711. doi: 10.3390/antiox10050711. Antioxidants (Basel). 2021. PMID: 33946318 Free PMC article.
Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction.
Chen S, Henderson A, Petriello MC, Romano KA, Gearing M, Miao J, Schell M, Sandoval-Espinola WJ, Tao J, Sha B, Graham M, Crooke R, Kleinridders A, Balskus EP, Rey FE, Morris AJ, Biddinger SB. Chen S, et al. Among authors: schell m. Cell Metab. 2019 Dec 3;30(6):1141-1151.e5. doi: 10.1016/j.cmet.2019.08.021. Epub 2019 Sep 19. Cell Metab. 2019. PMID: 31543404 Free article.
Insulin modulates emotional behavior through a serotonin-dependent mechanism.
Martin H, Bullich S, Martinat M, Chataigner M, Di Miceli M, Simon V, Clark S, Butler J, Schell M, Chopra S, Chaouloff F, Kleinridders A, Cota D, De Deurwaerdere P, Pénicaud L, Layé S, Guiard BP, Fioramonti X. Martin H, et al. Among authors: schell m. Mol Psychiatry. 2024 Jun;29(6):1610-1619. doi: 10.1038/s41380-022-01812-3. Epub 2022 Oct 7. Mol Psychiatry. 2024. PMID: 36207585
629 results