Zeng H - Search Results

1

Comprehensive exploration of isocitrate dehydrogenase (IDH) mutations: Tumorigenesis, drug discovery, and covalent inhibitor advances.

Gai C, Zeng H, Xu H, Chai X, Zou Y, Zhuang C, Ge G, Zhao Q. Gai C, et al. Among authors: zeng h. Eur J Med Chem. 2025 Jan 15;282:117041. doi: 10.1016/j.ejmech.2024.117041. Epub 2024 Nov 15. Eur J Med Chem. 2025. PMID: 39591851 Review.

2

Rationally Engineered CYP3A4 Fluorogenic Substrates for Functional Imaging Analysis and Drug-Drug Interaction Studies.

He RJ, Tian ZH, Huang J, Sun MR, Wei F, Li CY, Zeng HR, Zhang F, Guan XQ, Feng Y, Meng XM, Yang H, Ge GB. He RJ, et al. Among authors: zeng hr. J Med Chem. 2023 May 25;66(10):6743-6755. doi: 10.1021/acs.jmedchem.3c00101. Epub 2023 May 5. J Med Chem. 2023. PMID: 37145039

3

Rationally Engineered hCES2A Near-Infrared Fluorogenic Substrate for Functional Imaging and High-Throughput Inhibitor Screening.

Fan Y, Zhang T, Song Y, Sang Z, Zeng H, Liu P, Wang P, Ge G. Fan Y, et al. Among authors: zeng h. Anal Chem. 2023 Oct 24;95(42):15665-15672. doi: 10.1021/acs.analchem.3c02873. Epub 2023 Oct 2. Anal Chem. 2023. PMID: 37782032

4

Xanthohumol ameliorates drug-induced hepatic ferroptosis via activating Nrf2/xCT/GPX4 signaling pathway.

Deng Y, Chu X, Li Q, Zhu G, Hu J, Sun J, Zeng H, Huang J, Ge G. Deng Y, et al. Among authors: zeng h. Phytomedicine. 2024 Apr;126:155458. doi: 10.1016/j.phymed.2024.155458. Epub 2024 Feb 22. Phytomedicine. 2024. PMID: 38394733

5

Methylophiopogonanone A is a naturally occurring broad-spectrum inhibitor against human UDP-glucuronosyltransferases: Inhibition behaviours and implication in herb-drug interactions.

Zhou QH, Zhu GH, Song YQ, Que YF, He QQ, Tu DZ, Zeng HR, Qin WW, Ai CZ, Ge GB. Zhou QH, et al. Basic Clin Pharmacol Toxicol. 2021 Dec;129(6):437-449. doi: 10.1111/bcpt.13651. Epub 2021 Sep 28. Basic Clin Pharmacol Toxicol. 2021. PMID: 34478607 Free article.

6

Human UDP-glucuronosyltransferase 1As catalyze aristolochic acid D O-glucuronidation to form a lesser nephrotoxic glucuronide.

Tu DZ, Liu PQ, Zhu GH, Zeng HR, Deng YY, Huang J, Niu XT, Liu YF, Hu J, Liang XM, Finel M, Wang P, Ge GB. Tu DZ, et al. J Ethnopharmacol. 2024 Jun 28;328:118116. doi: 10.1016/j.jep.2024.118116. Epub 2024 Mar 26. J Ethnopharmacol. 2024. PMID: 38548118

7

Viola yedoensis Makino formula alleviates DNCB-induced atopic dermatitis by activating JAK2/STAT3 signaling pathway and promoting M2 macrophages polarization.

Zeng H, Zhao B, Zhang D, Rui X, Hou X, Chen X, Zhang B, Yuan Y, Deng H, Ge G. Zeng H, et al. Phytomedicine. 2022 Aug;103:154228. doi: 10.1016/j.phymed.2022.154228. Epub 2022 Jun 2. Phytomedicine. 2022. PMID: 35689898

8

Matrine suppresses lung cancer metastasis via targeting M2-like tumour-associated-macrophages polarization.

Zhao B, Hui X, Wang J, Zeng H, Yan Y, Hu Q, Ge G, Lei T. Zhao B, et al. Among authors: zeng h. Am J Cancer Res. 2021 Sep 15;11(9):4308-4328. eCollection 2021. Am J Cancer Res. 2021. PMID: 34659889 Free PMC article.

9

Emerging Pharmacotherapeutic Strategies to Overcome Undruggable Proteins in Cancer.

Lu Y, Yang Y, Zhu G, Zeng H, Fan Y, Guo F, Xu D, Wang B, Chen D, Ge G. Lu Y, et al. Among authors: zeng h. Int J Biol Sci. 2023 Jun 26;19(11):3360-3382. doi: 10.7150/ijbs.83026. eCollection 2023. Int J Biol Sci. 2023. PMID: 37496997 Free PMC article. Review.

10

Sophoridine Inhibits the Tumour Growth of Non-Small Lung Cancer by Inducing Macrophages M1 Polarisation via MAPK-Mediated Inflammatory Pathway.

Zhao B, Hui X, Zeng H, Yin Y, Huang J, Tang Q, Ge G, Lei T. Zhao B, et al. Among authors: zeng h. Front Oncol. 2021 Feb 24;11:634851. doi: 10.3389/fonc.2021.634851. eCollection 2021. Front Oncol. 2021. PMID: 33718223 Free PMC article.

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