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Page 1
NAD+ METABOLISM RESTRICTION BOOSTS HIGH-DOSE MELPHALAN EFFICACY IN PATIENTS WITH MULTIPLE MYELOMA.
Soncini D, Becherini P, Ladisa F, Ravera S, Chedere A, Gelli E, Giorgetti G, Martinuzzi C, Piacente F Dr, Mastracci L, Veneziano C Dr, Santamaria G Dr, Monacelli F, Ghanem MS, Cagnetta A, Guolo F Dr, Garibotto M, Aquino S, Passalacqua M, Bruzzone S, Bellotti A, Duchosal MA, Nahimana AA, Angelucci E, Nagasuma C Prof, Nencioni A, Lemoli RM, Cea M Prof. Soncini D, et al. Blood Adv. 2024 Dec 11:bloodadvances.2024013425. doi: 10.1182/bloodadvances.2024013425. Online ahead of print. Blood Adv. 2024. PMID: 39661983
Clonal hematopoiesis impacts frailty in newly diagnosed multiple myeloma patients: a retrospective multicenter analysis.
Gelli E, Martinuzzi C, Soncini D, Conticello C, Ladisa F, Giorgetti G, Truffelli D, Traverso I, Lai F, Guolo F, Miglino M, Cagnetta A, Laudisi A, Aquino S, Derudas D, Di Raimondo F, Coviello DA, Lemoli RM, Cea M. Gelli E, et al. Among authors: soncini d. Sci Rep. 2024 Nov 26;14(1):29394. doi: 10.1038/s41598-024-79748-7. Sci Rep. 2024. PMID: 39592674 Free PMC article.
Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells.
Astigiano C, Piacente F, Laugieri ME, Benzi A, Di Buduo CA, Miguel CP, Soncini D, Cea M, Antonelli A, Magnani M, Balduini A, De Flora A, Bruzzone S. Astigiano C, et al. Among authors: soncini d. Int J Mol Sci. 2023 Apr 4;24(7):6759. doi: 10.3390/ijms24076759. Int J Mol Sci. 2023. PMID: 37047732 Free PMC article.
Targeting the deacetylase SIRT6 unveils spliceosome deregulation as exploitable vulnerability for aggressive myeloma.
Gelli E, Soncini D, Becherini P, Martinuzzi C, Todoerti K, Cagnetta A, Aquino S, Guolo F, Miglino M, Bruzzone S, Nencioni A, Neri A, Lemoli RM, Cea M. Gelli E, et al. Among authors: soncini d. Blood Adv. 2023 Jul 25;7(14):3472-3478. doi: 10.1182/bloodadvances.2022009035. Blood Adv. 2023. PMID: 36897214 Free PMC article. No abstract available.
CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents.
Becherini P, Soncini D, Ravera S, Gelli E, Martinuzzi C, Giorgetti G, Cagnetta A, Guolo F, Ivaldi F, Miglino M, Aquino S, Todoerti K, Neri A, Benzi A, Passalacqua M, Nencioni A, Perrotta I, Gallo Cantafio ME, Amodio N, De Flora A, Bruzzone S, Lemoli RM, Cea M. Becherini P, et al. Among authors: soncini d. Antioxidants (Basel). 2023 Feb 15;12(2):494. doi: 10.3390/antiox12020494. Antioxidants (Basel). 2023. PMID: 36830052 Free PMC article.
Targeting the immune microenvironment in Waldenström macroglobulinemia via halting the CD40/CD40-ligand axis.
Sacco A, Desantis V, Celay J, Giustini V, Rigali F, Savino FD, Cea M, Soncini D, Cagnetta A, Solimando AG, D'Aliberti D, Spinelli S, Ramazzotti D, Almici C, Todoerti K, Neri A, Anastasia A, Tucci A, Motta M, Chiarini M, Kawano Y, Martinez-Climent JA, Piazza R, Roccaro AM. Sacco A, et al. Among authors: soncini d. Blood. 2023 May 25;141(21):2615-2628. doi: 10.1182/blood.2022019240. Blood. 2023. PMID: 36735903 Free article.
Therapeutic activation of G protein-coupled estrogen receptor 1 in Waldenström Macroglobulinemia.
Morelli E, Hunter ZR, Fulciniti M, Gullà A, Perrotta ID, Zuccalà V, Federico C, Juli G, Manzoni M, Ronchetti D, Romeo E, Gallo Cantafio ME, Soncini D, Maltese L, Rossi M, Roccaro AM, Cea M, Tassone P, Neri A, Treon SC, Munshi NC, Viglietto G, Amodio N. Morelli E, et al. Among authors: soncini d. Exp Hematol Oncol. 2022 Sep 12;11(1):54. doi: 10.1186/s40164-022-00305-x. Exp Hematol Oncol. 2022. PMID: 36096954 Free PMC article.
Apoptosis reprogramming triggered by splicing inhibitors sensitizes multiple myeloma cells to Venetoclax treatment.
Soncini D, Martinuzzi C, Becherini P, Gelli E, Ruberti S, Todoerti K, Mastracci L, Contini P, Cagnetta A, Laudisi A, Guolo F, Minetto P, Miglino M, Aquino S, Varaldo R, Reverberi D, Formica M, Passalacqua M, Nencioni A, Neri A, Samur MK, Munshi NC, Fulciniti M, Lemoli RM, Cea M. Soncini D, et al. Haematologica. 2022 Jun 1;107(6):1410-1426. doi: 10.3324/haematol.2021.279276. Haematologica. 2022. PMID: 34670358 Free PMC article.
The new small tyrosine kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs.
Soncini D, Orecchioni S, Ruberti S, Minetto P, Martinuzzi C, Agnelli L, Todoerti K, Cagnetta A, Miglino M, Clavio M, Contini P, Varaldo R, Bergamaschi M, Guolo F, Passalacqua M, Nencioni A, Monacelli F, Gobbi M, Neri A, Abbadessa G, Eathiraj S, Schwartz B, Bertolini F, Lemoli RM, Cea M. Soncini D, et al. Haematologica. 2020 Oct 1;105(10):2420-2431. doi: 10.3324/haematol.2019.224956. Haematologica. 2020. PMID: 33054082 Free PMC article.
Amino acid depletion triggered by ʟ-asparaginase sensitizes MM cells to carfilzomib by inducing mitochondria ROS-mediated cell death.
Soncini D, Minetto P, Martinuzzi C, Becherini P, Fenu V, Guolo F, Todoerti K, Calice G, Contini P, Miglino M, Rivoli G, Aquino S, Dominietto A, Cagnetta A, Passalacqua M, Bruzzone S, Nencioni A, Zucchetti M, Ceruti T, Neri A, Lemoli RM, Cea M. Soncini D, et al. Blood Adv. 2020 Sep 22;4(18):4312-4326. doi: 10.1182/bloodadvances.2020001639. Blood Adv. 2020. PMID: 32915979 Free PMC article.
33 results