Morgan GJ - Search Results

1

Predicting Structural Consequences of Antibody Light Chain N-Glycosylation in AL Amyloidosis.

Morgan GJ, Yung Z, Spencer BH, Sanchorawala V, Prokaeva T. Morgan GJ, et al. Pharmaceuticals (Basel). 2024 Nov 16;17(11):1542. doi: 10.3390/ph17111542. Pharmaceuticals (Basel). 2024. PMID: 39598451 Free PMC article.

2

Barriers to Small Molecule Drug Discovery for Systemic Amyloidosis.

Morgan GJ. Morgan GJ. Molecules. 2021 Jun 11;26(12):3571. doi: 10.3390/molecules26123571. Molecules. 2021. PMID: 34208058 Free PMC article.

3

Light Chain Stabilization: A Therapeutic Approach to Ameliorate AL Amyloidosis.

Morgan GJ, Buxbaum JN, Kelly JW. Morgan GJ, et al. Hemato. 2021 Dec;2(4):645-659. doi: 10.3390/hemato2040042. Epub 2021 Oct 5. Hemato. 2021. PMID: 35757512 Free PMC article.

4

Complete variable domain sequences of monoclonal antibody light chains identified from untargeted RNA sequencing data.

Nau A, Shen Y, Sanchorawala V, Prokaeva T, Morgan GJ. Nau A, et al. Among authors: morgan gj. Front Immunol. 2023 Apr 18;14:1167235. doi: 10.3389/fimmu.2023.1167235. eCollection 2023. Front Immunol. 2023. PMID: 37143670 Free PMC article.

5

Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains.

Wong S, West ME, Morgan GJ. Wong S, et al. Among authors: morgan gj. bioRxiv [Preprint]. 2023 Aug 28:2023.08.28.555139. doi: 10.1101/2023.08.28.555139. bioRxiv. 2023. Update in: Protein Sci. 2024 Mar;33(3):e4871. doi: 10.1002/pro.4871 PMID: 37693524 Free PMC article. Updated. Preprint.

6

Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains.

Wong S, West ME, Morgan GJ. Wong S, et al. Among authors: morgan gj. Protein Sci. 2024 Mar;33(3):e4871. doi: 10.1002/pro.4871. Protein Sci. 2024. PMID: 38100259

7

An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis.

Morgan G, Nau AN, Wong S, Spencer BH, Shen Y, Hua A, Bullard MJ, Sanchorawala V, Prokaeva T. Morgan G, et al. bioRxiv [Preprint]. 2024 Sep 15:2024.09.11.612490. doi: 10.1101/2024.09.11.612490. bioRxiv. 2024. Update in: Amyloid. 2024 Dec 6:1-10. doi: 10.1080/13506129.2024.2434899 PMID: 39314448 Free PMC article. Updated. Preprint.

8

An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis.

Morgan GJ, Nau AN, Wong S, Spencer BH, Shen Y, Hua A, Bullard MJ, Sanchorawala V, Prokaeva T. Morgan GJ, et al. Amyloid. 2024 Dec 6:1-10. doi: 10.1080/13506129.2024.2434899. Online ahead of print. Amyloid. 2024. PMID: 39641756

9

Pharmacological stabilization of the native state of full-length immunoglobulin light chains to treat light chain amyloidosis.

Yan NL, Morgan GJ, Petrassi HM, Wilson IA, Kelly JW. Yan NL, et al. Among authors: morgan gj. Curr Opin Chem Biol. 2023 Aug;75:102319. doi: 10.1016/j.cbpa.2023.102319. Epub 2023 Jun 6. Curr Opin Chem Biol. 2023. PMID: 37279624 Free PMC article. Review.

10

Structural basis for the stabilization of amyloidogenic immunoglobulin light chains by hydantoins.

Yan NL, Santos-Martins D, Rennella E, Sanchez BB, Chen JS, Kay LE, Wilson IA, Morgan GJ, Forli S, Kelly JW. Yan NL, et al. Among authors: morgan gj. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127356. doi: 10.1016/j.bmcl.2020.127356. Epub 2020 Jun 16. Bioorg Med Chem Lett. 2020. PMID: 32631553 Free PMC article.

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