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Page 1
Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging.
Yeh CY, Chini LCS, Davidson JW, Garcia GG, Gallagher MS, Freichels IT, Calubag MF, Rodgers AC, Green CL, Babygirija R, Sonsalla MM, Pak HH, Trautman ME, Hacker TA, Miller RA, Simcox JA, Lamming DW. Yeh CY, et al. Among authors: simcox ja. Nat Aging. 2024 Dec;4(12):1760-1771. doi: 10.1038/s43587-024-00744-7. Epub 2024 Nov 27. Nat Aging. 2024. PMID: 39604703
Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice.
Green CL, Trautman ME, Chaiyakul K, Jain R, Alam YH, Babygirija R, Pak HH, Sonsalla MM, Calubag MF, Yeh CY, Bleicher A, Novak G, Liu TT, Newman S, Ricke WA, Matkowskyj KA, Ong IM, Jang C, Simcox J, Lamming DW. Green CL, et al. Cell Metab. 2023 Nov 7;35(11):1976-1995.e6. doi: 10.1016/j.cmet.2023.10.005. Cell Metab. 2023. PMID: 37939658 Free PMC article.
The role of ATP citrate lyase in myelin formation and maintenance.
Schneider A, Won S, Armstrong EA, Cooper AJ, Suresh A, Rivera R, Barrett-Wilt G, Denu JM, Simcox JA, Svaren J. Schneider A, et al. Among authors: simcox ja. Glia. 2025 Jan;73(1):105-121. doi: 10.1002/glia.24620. Epub 2024 Sep 25. Glia. 2025. PMID: 39318247 Free PMC article.
Dietary isoleucine content defines the metabolic and molecular response to a Western diet.
Trautman ME, Green CL, MacArthur MR, Chaiyakul K, Alam YH, Yeh CY, Babygirija R, James I, Gilpin M, Zelenovskiy E, Green M, Marshall RN, Sonsalla MM, Flores V, Simcox JA, Ong IM, Malecki KC, Jang C, Lamming DW. Trautman ME, et al. Among authors: simcox ja. bioRxiv [Preprint]. 2024 Jun 3:2024.05.30.596340. doi: 10.1101/2024.05.30.596340. bioRxiv. 2024. PMID: 38895446 Free PMC article. Preprint.
Dietary lipid is largely deposited in skin and rapidly affects insulating properties.
Riley N, Kasza I, Hermsmeyer IDK, Trautman ME, Barrett-Wilt G, Jain R, Simcox JA, Yen CE, MacDougald OA, Lamming DW, Alexander CM. Riley N, et al. Among authors: simcox ja. Res Sq [Preprint]. 2024 Oct 7:rs.3.rs-3957002. doi: 10.21203/rs.3.rs-3957002/v1. Res Sq. 2024. PMID: 38464106 Free PMC article. Preprint.
21 results