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The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma.
Lightfuss OB, Kumar P, Li L, Shastri T, Newsam AD, Manara P, Alaoui AY, Parets DEH, Younes PA, Chahar D, Arumov A, Coughlin CA, Williams IP, Fattakhov N, Martinez AB, Landgren O, Schurer SC, Lemmon V, Maura F, Bilbao D, Feng Y, Al-Ali H, Schatz JH. Lightfuss OB, et al. Among authors: schurer sc. bioRxiv [Preprint]. 2024 Oct 26:2024.10.21.619489. doi: 10.1101/2024.10.21.619489. bioRxiv. 2024. PMID: 39484514 Free PMC article. Preprint.
Towards geospatially-resolved public-health surveillance via wastewater sequencing.
Tierney BT, Foox J, Ryon KA, Butler D, Damle N, Young BG, Mozsary C, Babler KM, Yin X, Carattini Y, Andrews D, Lucaci AG, Solle NS, Kumar N, Shukla B, Vidović D, Currall B, Williams SL, Schürer SC, Stevenson M, Amirali A, Beaver CC, Kobetz E, Boone MM, Reding B, Laine J, Comerford S, Lamar WE, Tallon JJ Jr, Wain Hirschberg J, Proszynski J, Al Ghalith G, Can Kurt K, Sharkey ME, Church GM, Grills GS, Solo-Gabriele HM, Mason CE. Tierney BT, et al. Among authors: schurer sc. Nat Commun. 2024 Sep 27;15(1):8386. doi: 10.1038/s41467-024-52427-x. Nat Commun. 2024. PMID: 39333485 Free PMC article.
Multiscale mapping of transcriptomic signatures for cardiotoxic drugs.
Hansen J, Xiong Y, Siddiq MM, Dhanan P, Hu B, Shewale B, Yadaw AS, Jayaraman G, Tolentino RE, Chen Y, Martinez P, Beaumont KG, Sebra R, Vidovic D, Schürer SC, Goldfarb J, Gallo JM, Birtwistle MR, Sobie EA, Azeloglu EU, Berger SI, Chan A, Schaniel C, Dubois NC, Iyengar R. Hansen J, et al. Among authors: schurer sc. Nat Commun. 2024 Sep 11;15(1):7968. doi: 10.1038/s41467-024-52145-4. Nat Commun. 2024. PMID: 39261481 Free PMC article.
Potent, Selective, and Orally Bioavailable Quinazoline-Based STK17A/B Dual Inhibitors.
Chaudhry S, Castro JR, Totiger TM, Afaghani J, Khurshid R, Nicholls M, Zhang Z, Schürer SC, Shah A, Taylor J, Feng Y. Chaudhry S, et al. Among authors: schurer sc. ACS Med Chem Lett. 2024 May 20;15(6):945-949. doi: 10.1021/acsmedchemlett.4c00125. eCollection 2024 Jun 13. ACS Med Chem Lett. 2024. PMID: 38894933
Correlative analysis of wastewater trends with clinical cases and hospitalizations through five dominant variant waves of COVID-19.
Zhan Q, Solo-Gabriele HM, Sharkey ME, Amirali A, Beaver CC, Boone MM, Comerford S, Cooper D, Cortizas EM, Cosculluela GA, Currall BB, Grills GS, Kobetz E, Kumar N, Laine J, Lamar WE, Lyu J, Mason CE, Reding BD, Roca MA, Schürer SC, Shukla BS, Solle NS, Suarez MM, Stevenson M, Tallon JJ Jr, Thomas C, Vidović D, Williams SL, Yin X, Zarnegarnia Y, Babler KM. Zhan Q, et al. Among authors: schurer sc. ACS ES T Water. 2023 Sep 8;3(9):2849-2862. doi: 10.1021/acsestwater.3c00032. Epub 2023 Aug 22. ACS ES T Water. 2023. PMID: 38487696 Free PMC article.
Kinome-Wide Virtual Screening by Multi-Task Deep Learning.
Hu J, Allen BK, Stathias V, Ayad NG, Schürer SC. Hu J, et al. Among authors: schurer sc. Int J Mol Sci. 2024 Feb 22;25(5):2538. doi: 10.3390/ijms25052538. Int J Mol Sci. 2024. PMID: 38473785 Free PMC article.
Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer.
Chowdhury S, Kennedy JJ, Ivey RG, Murillo OD, Hosseini N, Song X, Petralia F, Calinawan A, Savage SR, Berry AB, Reva B, Ozbek U, Krek A, Ma W, da Veiga Leprevost F, Ji J, Yoo S, Lin C, Voytovich UJ, Huang Y, Lee SH, Bergan L, Lorentzen TD, Mesri M, Rodriguez H, Hoofnagle AN, Herbert ZT, Nesvizhskii AI, Zhang B, Whiteaker JR, Fenyo D, McKerrow W, Wang J, Schürer SC, Stathias V, Chen XS, Barcellos-Hoff MH, Starr TK, Winterhoff BJ, Nelson AC, Mok SC, Kaufmann SH, Drescher C, Cieslik M, Wang P, Birrer MJ, Paulovich AG. Chowdhury S, et al. Among authors: schurer sc. Cell. 2024 Feb 15;187(4):1016. doi: 10.1016/j.cell.2024.01.016. Cell. 2024. PMID: 38364782 Free PMC article. No abstract available.
94 results