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Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations.
Hołubowicz R, Du SW, Felgner J, Smidak R, Choi EH, Palczewska G, Menezes CR, Dong Z, Gao F, Medani O, Yan AL, Hołubowicz MW, Chen PZ, Bassetto M, Risaliti E, Salom D, Workman JN, Kiser PD, Foik AT, Lyon DC, Newby GA, Liu DR, Felgner PL, Palczewski K. Hołubowicz R, et al. Among authors: felgner pl. Nat Biomed Eng. 2025 Jan;9(1):57-78. doi: 10.1038/s41551-024-01296-2. Epub 2024 Nov 28. Nat Biomed Eng. 2025. PMID: 39609561 Free PMC article.
Multifunctional Dendronized Polypeptides for Controlled Adjuvanticity.
Fan Z, Jan S, Hickey JC, Davies DH, Felgner J, Felgner PL, Guan Z. Fan Z, et al. Among authors: felgner j, felgner pl. Biomacromolecules. 2021 Dec 13;22(12):5074-5086. doi: 10.1021/acs.biomac.1c01052. Epub 2021 Nov 17. Biomacromolecules. 2021. PMID: 34788023
Administration of Multivalent Influenza Virus Recombinant Hemagglutinin Vaccine in Combination-Adjuvant Elicits Broad Reactivity Beyond the Vaccine Components.
Hernandez-Davies JE, Felgner J, Strohmeier S, Pone EJ, Jain A, Jan S, Nakajima R, Jasinskas A, Strahsburger E, Krammer F, Felgner PL, Davies DH. Hernandez-Davies JE, et al. Among authors: felgner j, felgner pl. Front Immunol. 2021 Jul 14;12:692151. doi: 10.3389/fimmu.2021.692151. eCollection 2021. Front Immunol. 2021. PMID: 34335601 Free PMC article.
Tuning Subunit Vaccines with Novel TLR Triagonist Adjuvants to Generate Protective Immune Responses against Coxiella burnetii.
Gilkes AP, Albin TJ, Manna S, Supnet M, Ruiz S, Tom J, Badten AJ, Jain A, Nakajima R, Felgner J, Davies DH, Stetkevich SA, Zlotnik A, Pearlman E, Nalca A, Felgner PL, Esser-Kahn AP, Burkhardt AM. Gilkes AP, et al. Among authors: felgner j, felgner pl. J Immunol. 2020 Feb 1;204(3):611-621. doi: 10.4049/jimmunol.1900991. Epub 2019 Dec 23. J Immunol. 2020. PMID: 31871024
Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray.
de Assis RR, Jain A, Nakajima R, Jasinskas A, Felgner J, Obiero JM, Norris PJ, Stone M, Simmons G, Bagri A, Irsch J, Schreiber M, Buser A, Holbro A, Battegay M, Hosimer P, Noesen C, Adenaiye O, Tai S, Hong F, Milton DK, Davies DH, Contestable P, Corash LM, Busch MP, Felgner PL, Khan S. de Assis RR, et al. Among authors: felgner j, felgner pl. Nat Commun. 2021 Jan 4;12(1):6. doi: 10.1038/s41467-020-20095-2. Nat Commun. 2021. PMID: 33397903 Free PMC article.
Discovery of potential diagnostic and vaccine antigens in herpes simplex virus 1 and 2 by proteome-wide antibody profiling.
Kalantari-Dehaghi M, Chun S, Chentoufi AA, Pablo J, Liang L, Dasgupta G, Molina DM, Jasinskas A, Nakajima-Sasaki R, Felgner J, Hermanson G, BenMohamed L, Felgner PL, Davies DH. Kalantari-Dehaghi M, et al. Among authors: felgner j, felgner pl. J Virol. 2012 Apr;86(8):4328-39. doi: 10.1128/JVI.05194-11. Epub 2012 Feb 8. J Virol. 2012. PMID: 22318154 Free PMC article.
Subunit Vaccines Using TLR Triagonist Combination Adjuvants Provide Protection Against Coxiella burnetii While Minimizing Reactogenic Responses.
Fratzke AP, Jan S, Felgner J, Liang L, Nakajima R, Jasinskas A, Manna S, Nihesh FN, Maiti S, Albin TJ, Esser-Kahn AP, Davies DH, Samuel JE, Felgner PL, Gregory AE. Fratzke AP, et al. Among authors: felgner j, felgner pl. Front Immunol. 2021 Mar 17;12:653092. doi: 10.3389/fimmu.2021.653092. eCollection 2021. Front Immunol. 2021. PMID: 33815413 Free PMC article.
Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants.
Hernandez-Davies JE, Dollinger EP, Pone EJ, Felgner J, Liang L, Strohmeier S, Jan S, Albin TJ, Jain A, Nakajima R, Jasinskas A, Krammer F, Esser-Kahn A, Felgner PL, Nie Q, Davies DH. Hernandez-Davies JE, et al. Among authors: felgner j, felgner pl. Sci Rep. 2022 Jun 2;12(1):9198. doi: 10.1038/s41598-022-12727-y. Sci Rep. 2022. PMID: 35654904 Free PMC article.
Measurement of antibody responses to Modified Vaccinia virus Ankara (MVA) and Dryvax(®) using proteome microarrays and development of recombinant protein ELISAs.
Hermanson G, Chun S, Felgner J, Tan X, Pablo J, Nakajima-Sasaki R, Molina DM, Felgner PL, Liang X, Davies DH. Hermanson G, et al. Among authors: felgner j, felgner pl. Vaccine. 2012 Jan 11;30(3):614-25. doi: 10.1016/j.vaccine.2011.11.021. Epub 2011 Nov 17. Vaccine. 2012. PMID: 22100890 Free PMC article.
253 results