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Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations.
Hołubowicz R, Du SW, Felgner J, Smidak R, Choi EH, Palczewska G, Menezes CR, Dong Z, Gao F, Medani O, Yan AL, Hołubowicz MW, Chen PZ, Bassetto M, Risaliti E, Salom D, Workman JN, Kiser PD, Foik AT, Lyon DC, Newby GA, Liu DR, Felgner PL, Palczewski K. Hołubowicz R, et al. Among authors: lyon dc. Nat Biomed Eng. 2024 Nov 28. doi: 10.1038/s41551-024-01296-2. Online ahead of print. Nat Biomed Eng. 2024. PMID: 39609561
Stress induced aging in mouse eye.
Xu Q, Rydz C, Nguyen Huu VA, Rocha L, Palomino La Torre C, Lee I, Cho W, Jabari M, Donello J, Lyon DC, Brooke RT, Horvath S, Weinreb RN, Ju WK, Foik A, Skowronska-Krawczyk D. Xu Q, et al. Among authors: lyon dc. Aging Cell. 2022 Dec;21(12):e13737. doi: 10.1111/acel.13737. Epub 2022 Nov 17. Aging Cell. 2022. PMID: 36397653 Free PMC article.
Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision.
Lewandowski D, Foik AT, Smidak R, Choi EH, Zhang J, Hoang T, Tworak A, Suh S, Leinonen H, Dong Z, Pinto AF, Tom E, Luu J, Lee J, Ma X, Bieberich E, Blackshaw S, Saghatelian A, Lyon DC, Skowronska-Krawczyk D, Tabaka M, Palczewski K. Lewandowski D, et al. Among authors: lyon dc. JCI Insight. 2022 Feb 22;7(4):e156301. doi: 10.1172/jci.insight.156301. JCI Insight. 2022. PMID: 35015730 Free PMC article.
55 results