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CD33-CD123 IF-THEN Gating Reduces Toxicity while Enhancing the Specificity and Memory Phenotype of AML-Targeting CAR-T Cells.
Jambon S, Sun J, Barman S, Muthugounder S, Bito XR, Shadfar A, Kovach AE, Wood BL, Thoppey Manoharan V, Morrissy AS, Bhojwani D, Wayne AS, Pulsipher MA, Kim YM, Asgharzadeh S, Parekh C, Moghimi B. Jambon S, et al. Among authors: kim ym. Blood Cancer Discov. 2025 Jan 8;6(1):55-72. doi: 10.1158/2643-3230.BCD-23-0258. Blood Cancer Discov. 2025. PMID: 39624992
Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia.
Gang EJ, Kim HN, Hsieh YT, Ruan Y, Ogana HA, Lee S, Pham J, Geng H, Park E, Klemm L, Willman CL, Carroll WL, Mittelman SD, Orgel E, Oberley MJ, Parekh C, Abdel-Azim H, Bhojwani D, Wayne AS, De Arcangelis A, Georges-Labouesse E, Wayner E, Bonig H, Minasyan A, Ten Hoeve J, Graeber TG, Müschen M, Heisterkamp N, Kim YM. Gang EJ, et al. Among authors: kim ym, kim hn. Blood. 2020 Jul 9;136(2):210-223. doi: 10.1182/blood.2019001417. Blood. 2020. PMID: 32219444 Free PMC article.
Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia.
Ruan Y, Kim HN, Ogana HA, Wan Z, Hurwitz S, Nichols C, Abdel-Azim N, Coba A, Seo S, Loh YE, Gang EJ, Abdel-Azim H, Hsieh CL, Lieber MR, Parekh C, Pal D, Bhojwani D, Durden DL, Kim YM. Ruan Y, et al. Among authors: kim ym, kim hn. Front Oncol. 2021 Dec 1;11:766888. doi: 10.3389/fonc.2021.766888. eCollection 2021. Front Oncol. 2021. PMID: 34926269 Free PMC article.
Artemis inhibition as a therapeutic strategy for acute lymphoblastic leukemia.
Ogana HA, Hurwitz S, Hsieh CL, Geng H, Müschen M, Bhojwani D, Wolf MA, Larocque J, Lieber MR, Kim YM. Ogana HA, et al. Among authors: kim ym. Front Cell Dev Biol. 2023 Mar 31;11:1134121. doi: 10.3389/fcell.2023.1134121. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37082620 Free PMC article.
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.
Park E, Gang EJ, Hsieh YT, Schaefer P, Chae S, Klemm L, Huantes S, Loh M, Conway EM, Kang ES, Hoe Koo H, Hofmann WK, Heisterkamp N, Pelus L, Keerthivasan G, Crispino J, Kahn M, Müschen M, Kim YM. Park E, et al. Among authors: kim ym. Blood. 2011 Aug 25;118(8):2191-9. doi: 10.1182/blood-2011-04-351239. Epub 2011 Jun 28. Blood. 2011. PMID: 21715311 Free PMC article.
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy.
Hsieh YT, Gang EJ, Geng H, Park E, Huantes S, Chudziak D, Dauber K, Schaefer P, Scharman C, Shimada H, Shojaee S, Klemm L, Parameswaran R, Loh M, Kang ES, Koo HH, Hofmann WK, Andrade J, Crooks GM, Willman CL, Müschen M, Papayannopoulou T, Heisterkamp N, Bönig H, Kim YM. Hsieh YT, et al. Among authors: kim ym. Blood. 2013 Mar 7;121(10):1814-8. doi: 10.1182/blood-2012-01-406272. Epub 2013 Jan 14. Blood. 2013. PMID: 23319569 Free PMC article.
Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition.
Saito K, Zhang Q, Yang H, Yamatani K, Ai T, Ruvolo V, Baran N, Cai T, Ma H, Jacamo R, Kuruvilla V, Imoto J, Kinjo S, Ikeo K, Moriya K, Suzuki K, Miida T, Kim YM, Vellano CP, Andreeff M, Marszalek JR, Tabe Y, Konopleva M. Saito K, et al. Among authors: kim ym. Blood Adv. 2021 Oct 26;5(20):4233-4255. doi: 10.1182/bloodadvances.2020003661. Blood Adv. 2021. PMID: 34507353 Free PMC article.
4,101 results