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Page 1
Loss of NUMB drives aggressive bladder cancer via a RHOA/ROCK/YAP signaling axis.
Tucci FA, Pennisi R, Rigiracciolo DC, Filippone MG, Bonfanti R, Romeo F, Freddi S, Guerrera E, Soriani C, Rodighiero S, Gunby RH, Jodice G, Sanguedolce F, Renne G, Fusco N, Di Fiore PP, Pruneri G, Bertalot G, Musi G, Vago G, Tosoni D, Pece S. Tucci FA, et al. Nat Commun. 2024 Dec 3;15(1):10378. doi: 10.1038/s41467-024-54246-6. Nat Commun. 2024. PMID: 39627202 Free PMC article.
CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer.
Filippone MG, Gaglio D, Bonfanti R, Tucci FA, Ceccacci E, Pennisi R, Bonanomi M, Jodice G, Tillhon M, Montani F, Bertalot G, Freddi S, Vecchi M, Taglialatela A, Romanenghi M, Romeo F, Bianco N, Munzone E, Sanguedolce F, Vago G, Viale G, Di Fiore PP, Minucci S, Alberghina L, Colleoni M, Veronesi P, Tosoni D, Pece S. Filippone MG, et al. Among authors: tucci fa. Nat Commun. 2022 May 12;13(1):2642. doi: 10.1038/s41467-022-30375-8. Nat Commun. 2022. PMID: 35550508 Free PMC article. Clinical Trial.
p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response.
Salemme V, Vedelago M, Sarcinella A, Moietta F, Piccolantonio A, Moiso E, Centonze G, Manco M, Guala A, Lamolinara A, Angelini C, Morellato A, Natalini D, Calogero R, Incarnato D, Oliviero S, Conti L, Iezzi M, Tosoni D, Bertalot G, Freddi S, Tucci FA, De Sanctis F, Frusteri C, Ugel S, Bronte V, Cavallo F, Provero P, Gai M, Taverna D, Turco E, Pece S, Defilippi P. Salemme V, et al. Among authors: tucci fa. Nat Commun. 2023 May 11;14(1):2350. doi: 10.1038/s41467-023-37824-y. Nat Commun. 2023. PMID: 37169737 Free PMC article.
The deleted in oral cancer (DOC1 aka CDK2AP1) tumor suppressor gene is downregulated in oral squamous cell carcinoma by multiple microRNAs.
Stabile R, Cabezas MR, Verhagen MP, Tucci FA, van den Bosch TPP, De Herdt MJ, van der Steen B, Nigg AL, Chen M, Ivan C, Shimizu M, Koljenović S, Hardillo JA, Verrijzer CP, Baatenburg de Jong RJ, Calin GA, Fodde R. Stabile R, et al. Among authors: tucci fa. Cell Death Dis. 2023 May 22;14(5):337. doi: 10.1038/s41419-023-05857-2. Cell Death Dis. 2023. PMID: 37217493 Free PMC article.
ZSCAN4+ mouse embryonic stem cells have an oxidative and flexible metabolic profile.
Troiano A, Pacelli C, Ruggieri V, Scrima R, Addeo M, Agriesti F, Lucci V, Cavaliere G, Mollica MP, Caterino M, Ruoppolo M, Paladino S, Sarnataro D, Visconte F, Tucci F, Lopriore P, Calabrò V, Capitanio N, Piccoli C, Falco G. Troiano A, et al. EMBO Rep. 2020 Jun 4;21(6):e48942. doi: 10.15252/embr.201948942. Epub 2020 May 18. EMBO Rep. 2020. PMID: 32424995 Free PMC article.
39 results