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Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.
Bonev B, Castelo-Branco G, Chen F, Codeluppi S, Corces MR, Fan J, Heiman M, Harris K, Inoue F, Kellis M, Levine A, Lotfollahi M, Luo C, Maynard KR, Nitzan M, Ramani V, Satijia R, Schirmer L, Shen Y, Sun N, Green GS, Theis F, Wang X, Welch JD, Gokce O, Konopka G, Liddelow S, Macosko E, Ali Bayraktar O, Habib N, Nowakowski TJ. Bonev B, et al. Among authors: chen f. Nat Neurosci. 2024 Dec;27(12):2292-2309. doi: 10.1038/s41593-024-01806-0. Epub 2024 Dec 3. Nat Neurosci. 2024. PMID: 39627587 Review.
Disease-associated astrocytes in Alzheimer's disease and aging.
Habib N, McCabe C, Medina S, Varshavsky M, Kitsberg D, Dvir-Szternfeld R, Green G, Dionne D, Nguyen L, Marshall JL, Chen F, Zhang F, Kaplan T, Regev A, Schwartz M. Habib N, et al. Among authors: chen f. Nat Neurosci. 2020 Jun;23(6):701-706. doi: 10.1038/s41593-020-0624-8. Epub 2020 Apr 27. Nat Neurosci. 2020. PMID: 32341542 Free PMC article.
RNA timestamps identify the age of single molecules in RNA sequencing.
Rodriques SG, Chen LM, Liu S, Zhong ED, Scherrer JR, Boyden ES, Chen F. Rodriques SG, et al. Among authors: chen lm, chen f. Nat Biotechnol. 2021 Mar;39(3):320-325. doi: 10.1038/s41587-020-0704-z. Epub 2020 Oct 19. Nat Biotechnol. 2021. PMID: 33077959 Free PMC article.
Robust decomposition of cell type mixtures in spatial transcriptomics.
Cable DM, Murray E, Zou LS, Goeva A, Macosko EZ, Chen F, Irizarry RA. Cable DM, et al. Among authors: chen f. Nat Biotechnol. 2022 Apr;40(4):517-526. doi: 10.1038/s41587-021-00830-w. Epub 2021 Feb 18. Nat Biotechnol. 2022. PMID: 33603203 Free PMC article.
Molecular logic of cellular diversification in the mouse cerebral cortex.
Di Bella DJ, Habibi E, Stickels RR, Scalia G, Brown J, Yadollahpour P, Yang SM, Abbate C, Biancalani T, Macosko EZ, Chen F, Regev A, Arlotta P. Di Bella DJ, et al. Among authors: chen f. Nature. 2021 Jul;595(7868):554-559. doi: 10.1038/s41586-021-03670-5. Epub 2021 Jun 23. Nature. 2021. PMID: 34163074 Free PMC article.
Joint single-cell measurements of nuclear proteins and RNA in vivo.
Chung H, Parkhurst CN, Magee EM, Phillips D, Habibi E, Chen F, Yeung BZ, Waldman J, Artis D, Regev A. Chung H, et al. Among authors: chen f. Nat Methods. 2021 Oct;18(10):1204-1212. doi: 10.1038/s41592-021-01278-1. Epub 2021 Oct 4. Nat Methods. 2021. PMID: 34608310 Free PMC article.
Dissecting mammalian spermatogenesis using spatial transcriptomics.
Chen H, Murray E, Sinha A, Laumas A, Li J, Lesman D, Nie X, Hotaling J, Guo J, Cairns BR, Macosko EZ, Cheng CY, Chen F. Chen H, et al. Among authors: chen f. Cell Rep. 2021 Nov 2;37(5):109915. doi: 10.1016/j.celrep.2021.109915. Cell Rep. 2021. PMID: 34731600 Free PMC article.
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