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Opportunities and challenges of single-cell and spatially resolved genomics methods for neuroscience discovery.
Bonev B, Castelo-Branco G, Chen F, Codeluppi S, Corces MR, Fan J, Heiman M, Harris K, Inoue F, Kellis M, Levine A, Lotfollahi M, Luo C, Maynard KR, Nitzan M, Ramani V, Satijia R, Schirmer L, Shen Y, Sun N, Green GS, Theis F, Wang X, Welch JD, Gokce O, Konopka G, Liddelow S, Macosko E, Ali Bayraktar O, Habib N, Nowakowski TJ. Bonev B, et al. Among authors: schirmer l. Nat Neurosci. 2024 Dec;27(12):2292-2309. doi: 10.1038/s41593-024-01806-0. Epub 2024 Dec 3. Nat Neurosci. 2024. PMID: 39627587 Review.
Long-term dynamics of multiple sclerosis iron rim lesions.
Weber CE, Wittayer M, Kraemer M, Dabringhaus A, Bail K, Platten M, Schirmer L, Gass A, Eisele P. Weber CE, et al. Among authors: schirmer l. Mult Scler Relat Disord. 2022 Jan;57:103340. doi: 10.1016/j.msard.2021.103340. Epub 2021 Oct 18. Mult Scler Relat Disord. 2022. PMID: 35158450
Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology.
Deigendesch N, Sironi L, Kutza M, Wischnewski S, Fuchs V, Hench J, Frank A, Nienhold R, Mertz KD, Cathomas G, Matter MS, Siegemund M, Tolnay M, Schirmer L, Pröbstel AK, Tzankov A, Frank S. Deigendesch N, et al. Among authors: schirmer l. Acta Neuropathol. 2020 Oct;140(4):583-586. doi: 10.1007/s00401-020-02213-y. Epub 2020 Aug 26. Acta Neuropathol. 2020. PMID: 32851506 Free PMC article. No abstract available.
Neurotoxic reactive astrocytes are induced by activated microglia.
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA. Liddelow SA, et al. Among authors: schirmer l. Nature. 2017 Jan 26;541(7638):481-487. doi: 10.1038/nature21029. Epub 2017 Jan 18. Nature. 2017. PMID: 28099414 Free PMC article.
Neuronal vulnerability and multilineage diversity in multiple sclerosis.
Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, Vistnes S, Stockley JH, Young A, Steindel M, Tung B, Goyal N, Bhaduri A, Mayer S, Engler JB, Bayraktar OA, Franklin RJM, Haeussler M, Reynolds R, Schafer DP, Friese MA, Shiow LR, Kriegstein AR, Rowitch DH. Schirmer L, et al. Nature. 2019 Sep;573(7772):75-82. doi: 10.1038/s41586-019-1404-z. Epub 2019 Jul 17. Nature. 2019. PMID: 31316211 Free PMC article.
Single-cell analysis of prenatal and postnatal human cortical development.
Velmeshev D, Perez Y, Yan Z, Valencia JE, Castaneda-Castellanos DR, Wang L, Schirmer L, Mayer S, Wick B, Wang S, Nowakowski TJ, Paredes M, Huang EJ, Kriegstein AR. Velmeshev D, et al. Among authors: schirmer l. Science. 2023 Oct 13;382(6667):eadf0834. doi: 10.1126/science.adf0834. Epub 2023 Oct 13. Science. 2023. PMID: 37824647 Free PMC article.
Cell type mapping reveals tissue niches and interactions in subcortical multiple sclerosis lesions.
Lerma-Martin C, Badia-I-Mompel P, Ramirez Flores RO, Sekol P, Schäfer PSL, Riedl CJ, Hofmann A, Thäwel T, Wünnemann F, Ibarra-Arellano MA, Trobisch T, Eisele P, Schapiro D, Haeussler M, Hametner S, Saez-Rodriguez J, Schirmer L. Lerma-Martin C, et al. Among authors: schirmer l. Nat Neurosci. 2024 Dec;27(12):2354-2365. doi: 10.1038/s41593-024-01796-z. Epub 2024 Nov 5. Nat Neurosci. 2024. PMID: 39501036 Free PMC article.
105 results