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Synaptotagmin-11 deficiency mediates schizophrenia-like behaviors in mice via dopamine over-transmission.
Chen Y, Gu Y, Wang B, Wei A, Dong N, Jiang Y, Liu X, Zhu L, Zhu F, Tan T, Jing Z, Mao F, Zhang Y, Yao J, Yang Y, Wang H, Wu H, Li H, Zheng C, Duan X, Huo J, Wu X, Hu S, Zhao A, Li Z, Cheng X, Qin Y, Song Q, Zhan S, Qu Q, Guan F, Xu H, Kang X, Wang C. Chen Y, et al. Among authors: gu y. Nat Commun. 2024 Dec 4;15(1):10571. doi: 10.1038/s41467-024-54604-4. Nat Commun. 2024. PMID: 39632880 Free PMC article.
An ACC-VTA-ACC positive-feedback loop mediates the persistence of neuropathic pain and emotional consequences.
Song Q, Wei A, Xu H, Gu Y, Jiang Y, Dong N, Zheng C, Wang Q, Gao M, Sun S, Duan X, Chen Y, Wang B, Huo J, Yao J, Wu H, Li H, Wu X, Jing Z, Liu X, Yang Y, Hu S, Zhao A, Wang H, Cheng X, Qin Y, Qu Q, Chen T, Zhou Z, Chai Z, Kang X, Wei F, Wang C. Song Q, et al. Among authors: gu y. Nat Neurosci. 2024 Feb;27(2):272-285. doi: 10.1038/s41593-023-01519-w. Epub 2024 Jan 3. Nat Neurosci. 2024. PMID: 38172439
Synaptotagmin-1 is a bidirectional Ca2+ sensor for neuronal endocytosis.
Chen Y, Hu S, Wu X, Xie Z, Wang Y, Wang B, Li X, Pei Y, Gu Y, Huang K, Huo J, Wei A, Bi C, Lu Z, Song Q, Xu H, Kang X, Shao S, Long J, Liu J, Zhou Z, Huang R, Chai Z, Wang C. Chen Y, et al. Among authors: gu y. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2111051119. doi: 10.1073/pnas.2111051119. Epub 2022 May 10. Proc Natl Acad Sci U S A. 2022. PMID: 35537054 Free PMC article.
Halcinonide activates smoothened to ameliorate ischemic stroke injury.
Liu J, Zhao W, Kang J, Li X, Han L, Hu Z, Zhou J, Meng X, Gao X, Zhang Y, Gu Y, Liu X, Chen X. Liu J, et al. Among authors: gu y. Life Sci. 2024 Dec 20:123324. doi: 10.1016/j.lfs.2024.123324. Online ahead of print. Life Sci. 2024. PMID: 39710062
Variants in EP400, encoding a chromatin remodeler, cause epilepsy with neurodevelopmental disorders.
Luo S, Wang PY, Zhou P, Zhang WJ, Gu YJ, Liang XY, Zhang JW, Luo JX, Zhang HW, Lan S, Zhang TT, Yang JH, Sun SZ, Guo XY, Wang JL, Deng LF, Xu ZH, Jin L, He YY, Ye ZL, Gu WY, Li BM, Shi YW, Liu XR, Yan HJ, Yi YH, Jiang YW, Mao X, Li WL, Meng H, Liao WP. Luo S, et al. Among authors: gu yj. Am J Hum Genet. 2024 Dec 17:S0002-9297(24)00419-1. doi: 10.1016/j.ajhg.2024.11.010. Online ahead of print. Am J Hum Genet. 2024. PMID: 39708813
Religion, spirituality, and DNA methylation in HPA-axis genes among Hispanic/Latino adults.
Zhen-Duan J, Canenguez KM, Wilson AE, Gu Y, Valluri HG, Chavez AD, Argentieri MA, Schachter AB, Wu H, Baccarelli AA, Daviglus ML, Wassertheil-Smoller S, Warner ET, Shields AE. Zhen-Duan J, et al. Among authors: gu y. Epigenomics. 2024 Dec 20:1-12. doi: 10.1080/17501911.2024.2442293. Online ahead of print. Epigenomics. 2024. PMID: 39707707
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