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Page 1
Isoprene nitrates drive new particle formation in Amazon's upper troposphere.
Curtius J, Heinritzi M, Beck LJ, Pöhlker ML, Tripathi N, Krumm BE, Holzbeck P, Nussbaumer CM, Hernández Pardo L, Klimach T, Barmpounis K, Andersen ST, Bardakov R, Bohn B, Cecchini MA, Chaboureau JP, Dauhut T, Dienhart D, Dörich R, Edtbauer A, Giez A, Hartmann A, Holanda BA, Joppe P, Kaiser K, Keber T, Klebach H, Krüger OO, Kürten A, Mallaun C, Marno D, Martinez M, Monteiro C, Nelson C, Ort L, Raj SS, Richter S, Ringsdorf A, Rocha F, Simon M, Sreekumar S, Tsokankunku A, Unfer GR, Valenti ID, Wang N, Zahn A, Zauner-Wieczorek M, Albrecht RI, Andreae MO, Artaxo P, Crowley JN, Fischer H, Harder H, Herdies DL, Machado LAT, Pöhlker C, Pöschl U, Possner A, Pozzer A, Schneider J, Williams J, Lelieveld J. Curtius J, et al. Among authors: krumm be. Nature. 2024 Dec;636(8041):124-130. doi: 10.1038/s41586-024-08192-4. Epub 2024 Dec 4. Nature. 2024. PMID: 39633195 Free PMC article.
Structure-guided design of a peripherally restricted chemogenetic system.
Kang HJ, Krumm BE, Tassou A, Geron M, DiBerto JF, Kapolka NJ, Gumpper RH, Sakamoto K, Dewran Kocak D, Olsen RHJ, Huang XP, Zhang S, Huang KL, Zaidi SA, Nguyen MT, Jo MJ, Katritch V, Fay JF, Scherrer G, Roth BL. Kang HJ, et al. Among authors: krumm be. Cell. 2024 Nov 25:S0092-8674(24)01275-3. doi: 10.1016/j.cell.2024.11.001. Online ahead of print. Cell. 2024. PMID: 39631393
High-affinity agonists reveal recognition motifs for the MRGPRD GPCR.
Wang C, Liu Y, Lanier M, Yeager A, Singh I, Gumpper RH, Krumm BE, DeLeon C, Zhang S, Boehm M, Pittner R, Baron A, Dvorak L, Bacon C, Shoichet BK, Martinborough E, Fay JF, Cao C, Roth BL. Wang C, et al. Among authors: krumm be. Cell Rep. 2024 Dec 24;43(12):114942. doi: 10.1016/j.celrep.2024.114942. Epub 2024 Nov 23. Cell Rep. 2024. PMID: 39580805 Free article.
A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
Knight KM, Krumm BE, Kapolka NJ, Ludlam WG, Cui M, Mani S, Prytkova I, Obarow EG, Lefevre TJ, Wei W, Ma N, Huang XP, Fay JF, Vaidehi N, Smrcka AV, Slesinger PA, Logothetis DE, Martemyanov KA, Roth BL, Dohlman HG. Knight KM, et al. Among authors: krumm be. Nat Commun. 2024 Aug 5;15(1):6643. doi: 10.1038/s41467-024-50964-z. Nat Commun. 2024. PMID: 39103320 Free PMC article.
Molecular glues as potential GPCR therapeutics.
Roth BL, Krumm BE. Roth BL, et al. Among authors: krumm be. Biochem Pharmacol. 2024 Oct;228:116402. doi: 10.1016/j.bcp.2024.116402. Epub 2024 Jun 28. Biochem Pharmacol. 2024. PMID: 38945274 Review.
Structural genomics of the human dopamine receptor system.
Xu P, Huang S, Krumm BE, Zhuang Y, Mao C, Zhang Y, Wang Y, Huang XP, Liu YF, He X, Li H, Yin W, Jiang Y, Zhang Y, Roth BL, Xu HE. Xu P, et al. Among authors: krumm be. Cell Res. 2023 Aug;33(8):604-616. doi: 10.1038/s41422-023-00808-0. Epub 2023 May 23. Cell Res. 2023. PMID: 37221270 Free PMC article.
Ligand and G-protein selectivity in the κ-opioid receptor.
Han J, Zhang J, Nazarova AL, Bernhard SM, Krumm BE, Zhao L, Lam JH, Rangari VA, Majumdar S, Nichols DE, Katritch V, Yuan P, Fay JF, Che T. Han J, et al. Among authors: krumm be. Nature. 2023 May;617(7960):417-425. doi: 10.1038/s41586-023-06030-7. Epub 2023 May 3. Nature. 2023. PMID: 37138078 Free PMC article.
27 results