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Page 1
Low Penetrance Sarcomere Variants Contribute to Additive Risk in Hypertrophic Cardiomyopathy.
Meisner JK, Renberg A, Smith ED, Tsan YC, Elder B, Bullard A, Merritt O, Zheng SL, Lakdawala N, Owens A, Ryan TD, Miller EM, Rossano J, Lin KY, Claggett B, Ashley E, Michels M, Lampert R, Stendahl JC, Abrahams D, Semsarian C, Parikh VN, Wheeler M, Ingles J, Day SM, Saberi S, Russell MW, Previs M, Ho C, Ware JS, Helms AS. Meisner JK, et al. Among authors: previs m. Circulation. 2024 Dec 5. doi: 10.1161/CIRCULATIONAHA.124.069398. Online ahead of print. Circulation. 2024. PMID: 39633578
Effects of MYBPC3 loss-of-function mutations preceding hypertrophic cardiomyopathy.
Helms AS, Tang VT, O'Leary TS, Friedline S, Wauchope M, Arora A, Wasserman AH, Smith ED, Lee LM, Wen XW, Shavit JA, Liu AP, Previs MJ, Day SM. Helms AS, et al. Among authors: previs mj. JCI Insight. 2020 Jan 30;5(2):e133782. doi: 10.1172/jci.insight.133782. JCI Insight. 2020. PMID: 31877118 Free PMC article.
Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy.
Previs MJ, O'Leary TS, Morley MP, Palmer BM, LeWinter M, Yob JM, Pagani FD, Petucci C, Kim MS, Margulies KB, Arany Z, Kelly DP, Day SM. Previs MJ, et al. Circ Heart Fail. 2022 Jun;15(6):e009521. doi: 10.1161/CIRCHEARTFAILURE.121.009521. Epub 2022 May 11. Circ Heart Fail. 2022. PMID: 35543134 Free PMC article.
Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform.
Tsan YC, DePalma SJ, Zhao YT, Capilnasiu A, Wu YW, Elder B, Panse I, Ufford K, Matera DL, Friedline S, O'Leary TS, Wubshet N, Ho KKY, Previs MJ, Nordsletten D, Isom LL, Baker BM, Liu AP, Helms AS. Tsan YC, et al. Among authors: previs mj. Nat Commun. 2021 Oct 25;12(1):6167. doi: 10.1038/s41467-021-26496-1. Nat Commun. 2021. PMID: 34697315 Free PMC article.
MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy.
Steczina S, Mohran S, Bailey LRJ, McMillen TS, Kooiker KB, Wood NB, Davis J, Previs MJ, Olivotto I, Pioner JM, Geeves MA, Poggesi C, Regnier M. Steczina S, et al. Among authors: previs mj. J Mol Cell Cardiol. 2024 Jun;191:27-39. doi: 10.1016/j.yjmcc.2024.04.010. Epub 2024 Apr 20. J Mol Cell Cardiol. 2024. PMID: 38648963
Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility.
Lynch TL 4th, Kumar M, McNamara JW, Kuster DWD, Sivaguru M, Singh RR, Previs MJ, Lee KH, Kuffel G, Zilliox MJ, Lin BL, Ma W, Gibson AM, Blaxall BC, Nieman ML, Lorenz JN, Leichter DM, Leary OP, Janssen PML, de Tombe PP, Gilbert RJ, Craig R, Irving T, Warshaw DM, Sadayappan S. Lynch TL 4th, et al. Among authors: previs mj. J Mol Cell Cardiol. 2021 Jul;156:33-44. doi: 10.1016/j.yjmcc.2021.03.009. Epub 2021 Mar 26. J Mol Cell Cardiol. 2021. PMID: 33781820 Free PMC article.
51 results