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Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations.
Di Federico A, Angelicola S, Frascino M, Siracusa I, Bisanti B, Ruzzi F, Semprini MS, De Jonge H, De Giglio A, Sperandi F, Brocchi S, Melotti B, Giunchi F, Gruppioni E, Altimari A, Lollini PL, Ardizzoni A, Palladini A, Gelsomino F. Di Federico A, et al. Among authors: de jonge h. JCO Precis Oncol. 2024 Dec;8:e2400240. doi: 10.1200/PO.24.00240. Epub 2024 Dec 5. JCO Precis Oncol. 2024. PMID: 39637338 Free PMC article.
PD-L1 and IFN-γ modulate Non-Small Cell Lung Cancer (NSCLC) cell plasticity associated to immune checkpoint inhibitor (ICI)-mediated hyperprogressive disease (HPD).
Angelicola S, Giunchi F, Ruzzi F, Frascino M, Pitzalis M, Scalambra L, Semprini MS, Pittino OM, Cappello C, Siracusa I, Chillico IC, Di Noia M, Turato C, De Siervi S, Lescai F, Ciavattini T, Lopatriello G, Bertoli L, De Jonge H, Iamele L, Altimari A, Gruppioni E, Ardizzoni A, Rossato M, Gelsomino F, Lollini PL, Palladini A. Angelicola S, et al. Among authors: de jonge h. J Transl Med. 2025 Jan 2;23(1):2. doi: 10.1186/s12967-024-06023-8. J Transl Med. 2025. PMID: 39748404 Free PMC article.
Peptides inhibiting the assembly of monomeric human l-lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells.
Stefan A, Gentilucci L, Ruffolo F, Rossi V, Sordi S, He T, di Stefano G, Santino F, Brigotti M, Scotti C, Iamele L, de Jonge H, Piaz FD, Santarcangelo DR, Hochkoeppler A. Stefan A, et al. Among authors: de jonge h. Protein Sci. 2024 Oct;33(10):e5161. doi: 10.1002/pro.5161. Protein Sci. 2024. PMID: 39276013 Free PMC article.
A multimodal molecular imaging approach targeting urokinase plasminogen activator receptor for the diagnosis, resection and surveillance of urothelial cell carcinoma.
Baart VM, van der Horst G, Deken MM, Bhairosingh SS, Schomann T, Sier VQ, van der Mark MH, Iamele L, de Jonge H, Resnati M, Mazar AP, Pelger RCM, van der Pluijm G, Kuppen PJK, Vahrmeijer AL, Sier CFM. Baart VM, et al. Among authors: de jonge h. Eur J Cancer. 2021 Mar;146:11-20. doi: 10.1016/j.ejca.2021.01.001. Epub 2021 Feb 6. Eur J Cancer. 2021. PMID: 33561783 Free article.
A Novel HGF/SF Receptor (MET) Agonist Transiently Delays the Disease Progression in an Amyotrophic Lateral Sclerosis Mouse Model by Promoting Neuronal Survival and Dampening the Immune Dysregulation.
Vallarola A, Tortarolo M, De Gioia R, Iamele L, de Jonge H, de Nola G, Bovio E, Pasetto L, Bonetto V, Freschi M, Bendotti C, Gherardi E. Vallarola A, et al. Among authors: de nola g, de jonge h, de gioia r. Int J Mol Sci. 2020 Nov 12;21(22):8542. doi: 10.3390/ijms21228542. Int J Mol Sci. 2020. PMID: 33198383 Free PMC article.
Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist.
de Nola G, Leclercq B, Mougel A, Taront S, Simonneau C, Forneris F, Adriaenssens E, Drobecq H, Iamele L, Dubuquoy L, Melnyk O, Gherardi E, de Jonge H, Vicogne J. de Nola G, et al. Among authors: de jonge h. Life Sci Alliance. 2022 Jul 29;5(12):e202201424. doi: 10.26508/lsa.202201424. Life Sci Alliance. 2022. PMID: 35905995 Free PMC article.
395 results