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Seraph-100 hemoperfusion for management of severe COVID-19: Assessment of serum and plasma analytes pre- and post-filtration.
Rouse M, Gann ER, Brandsma J, Sugiharto VA, Robertson H, Genzor P, Chen HW, Simons MP, Schobel SA, Chenoweth JG, Jenkins SA, Clark DV, Della Volpe J, Chitty S, Rivera IM, Lewis M, Park C, Parikh A, Vir P, Stewart IJ, Pratt KP. Rouse M, et al. Among authors: simons mp. Blood Purif. 2024 Dec 11:1-16. doi: 10.1159/000542995. Online ahead of print. Blood Purif. 2024. PMID: 39662058 Free article.
Neuroinflammation in Alzheimer disease.
Heneka MT, van der Flier WM, Jessen F, Hoozemanns J, Thal DR, Boche D, Brosseron F, Teunissen C, Zetterberg H, Jacobs AH, Edison P, Ramirez A, Cruchaga C, Lambert JC, Laza AR, Sanchez-Mut JV, Fischer A, Castro-Gomez S, Stein TD, Kleineidam L, Wagner M, Neher JJ, Cunningham C, Singhrao SK, Prinz M, Glass CK, Schlachetzki JCM, Butovsky O, Kleemann K, De Jaeger PL, Scheiblich H, Brown GC, Landreth G, Moutinho M, Grutzendler J, Gomez-Nicola D, McManus RM, Andreasson K, Ising C, Karabag D, Baker DJ, Liddelow SA, Verkhratsky A, Tansey M, Monsonego A, Aigner L, Dorothée G, Nave KA, Simons M, Constantin G, Rosenzweig N, Pascual A, Petzold GC, Kipnis J, Venegas C, Colonna M, Walter J, Tenner AJ, O'Banion MK, Steinert JR, Feinstein DL, Sastre M, Bhaskar K, Hong S, Schafer DP, Golde T, Ransohoff RM, Morgan D, Breitner J, Mancuso R, Riechers SP. Heneka MT, et al. Among authors: simons m. Nat Rev Immunol. 2024 Dec 9. doi: 10.1038/s41577-024-01104-7. Online ahead of print. Nat Rev Immunol. 2024. PMID: 39653749 Review.
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Among authors: simons m. Immunity. 2024 Dec 4:S1074-7613(24)00539-9. doi: 10.1016/j.immuni.2024.11.024. Online ahead of print. Immunity. 2024. PMID: 39637851 No abstract available.
Myeloid cell-specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
Dinkel L, Hummel S, Zenatti V, Malara M, Tillmann Y, Colombo A, Monasor LS, Suh JH, Logan T, Roth S, Paeger L, Hoffelner P, Bludau O, Schmidt A, Müller SA, Schifferer M, Nuscher B, Njavro JR, Prestel M, Bartos LM, Wind-Mark K, Slemann L, Hoermann L, Kunte ST, Gnörich J, Lindner S, Simons M, Herms J, Paquet D, Lichtenthaler SF, Bartenstein P, Franzmeier N, Liesz A, Grosche A, Bremova-Ertl T, Catarino C, Beblo S, Bergner C, Schneider SA, Strupp M, Di Paolo G, Brendel M, Tahirovic S. Dinkel L, et al. Among authors: simons m. Sci Transl Med. 2024 Dec 4;16(776):eadl4616. doi: 10.1126/scitranslmed.adl4616. Epub 2024 Dec 4. Sci Transl Med. 2024. PMID: 39630885
Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
Topper MJ, Guarnieri JW, Haltom JA, Chadburn A, Cope H, Frere J, An J, Borczuk A, Sinha S, Kim J, Park J, Butler D, Meydan C, Foox J, Bram Y, Richard SA, Epsi NJ, Agan B, Chenoweth JG, Simons MP, Tribble D, Burgess T, Dalgard C, Heise MT, Moorman NJ, Baxter VK, Madden EA, Taft-Benz SA, Anderson EJ, Sanders WA, Dickmander RJ, Beigel K, Widjaja GA, Janssen KA, Lie T, Murdock DG, Angelin A, Soto Albrecht YE, Olali AZ, Cen Z, Dybas J, Priebe W, Emmett MR, Best SM, Kelsey Johnson M, Trovao NS, Clark KB, Zaksas V, Meller R, Grabham P, Schisler JC, Moraes-Vieira PM, Pollett S, Mason CE, Syrkin Wurtele E, Taylor D, Schwartz RE, Beheshti A, Wallace DC, Baylin SB. Topper MJ, et al. Among authors: simons mp. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2401968121. doi: 10.1073/pnas.2401968121. Epub 2024 Nov 27. Proc Natl Acad Sci U S A. 2024. PMID: 39602262 Free PMC article.
Evaluation of the recently established Dutch nationwide Archipelago of Ovarian Cancer Research biobank.
Zelisse HS, van Gent MDJM, Mom CH, de Ridder S, Snijders MLH, Heeling M, Stoter M, Broeks A, Horlings HM, Lok CAR, Bosch SL, Piek JM, Bart J, Reyners AKL, Wisman GBA, Yigit R, Boere IA, Collée M, Groenendijk FH, Jansen MPHM, Roes EM, Hofhuis W, Hoogduin KJ, Alcalá LSM, Smedts HPM, Makkus ACF, Nieuwenhuyzen-de Boer GM, van Es N, Vencken PMLH, van Altena AM, Simons M, Hazelbag HM, Kagie MJ, Aliredjo R, Bonestroo TJJ, Bosse T, de Kroon CD, Brinkhuis M, Janssen MJ, Koster NC, Kruse AJ, Gerestein CG, Jonges TGN, Zweemer RP, Kooreman LFS, Lambrechts S, Ebisch IMW, de Kievit van der Heijden IM, Voorham QJ, van der Aa MA, Belien JAM, van de Vijver MJ, Dijk F; Archipelago of Ovarian Cancer Research Consortium. Zelisse HS, et al. Among authors: simons m. Ann Diagn Pathol. 2025 Feb;74:152411. doi: 10.1016/j.anndiagpath.2024.152411. Epub 2024 Nov 19. Ann Diagn Pathol. 2025. PMID: 39591762 Free article.
DNA repair and anti-cancer mechanisms in the long-lived bowhead whale.
Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, Lu JY, Zheng Z, Perelli L, Gurreri E, Zhang L, Guo J, Korotkov A, Volobaev V, Biashad SA, Zhang Z, Heid J, Maslov A, Sun S, Wu Z, Gigas J, Hillpot E, Martinez J, Lee M, Williams A, Gilman A, Hamilton N, Haseljic E, Patel A, Straight M, Miller N, Ablaeva J, Tam LM, Couderc C, Hoopman M, Moritz R, Fujii S, Hayman DJ, Liu H, Cai Y, Leung AKL, Simons MJP, Zhang Z, Nelson CB, Abegglen LM, Schiffman JD, Gladyshev VN, Modesti M, Genovese G, Vijg J, Seluanov A, Gorbunova V. Firsanov D, et al. Among authors: simons mjp. bioRxiv [Preprint]. 2024 Nov 5:2023.05.07.539748. doi: 10.1101/2023.05.07.539748. bioRxiv. 2024. PMID: 39574710 Free PMC article. Preprint.
White matter aging and its impact on brain function.
Groh J, Simons M. Groh J, et al. Among authors: simons m. Neuron. 2024 Nov 6:S0896-6273(24)00767-0. doi: 10.1016/j.neuron.2024.10.019. Online ahead of print. Neuron. 2024. PMID: 39541972 Free article. Review.
1,539 results