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551 results

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Page 1
Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons.
Marvian AT, Strauss T, Tang Q, Tuck BJ, Keeling S, Rüdiger D, Mirzazadeh Dizaji N, Mohammad-Beigi H, Nuscher B, Chakraborty P, Sutherland DS, McEwan WA, Köglsperger T, Zahler S, Zweckstetter M, Lichtenthaler SF, Wurst W, Schwarz S, Höglinger G. Marvian AT, et al. Among authors: wurst w. Mol Neurodegener. 2024 Dec 31;19(1):100. doi: 10.1186/s13024-024-00786-w. Mol Neurodegener. 2024. PMID: 39736627 Free PMC article.
X-linked deletion of Crossfirre, Firre, and Dxz4 in vivo uncovers diverse phenotypes and combinatorial effects on autosomes.
Hasenbein TP, Hoelzl S, Smith ZD, Gerhardinger C, Gonner MOC, Aguilar-Pimentel A, Amarie OV, Becker L, Calzada-Wack J, Dragano NRV, da Silva-Buttkus P, Garrett L, Hölter SM, Kraiger M, Östereicher MA, Rathkolb B, Sanz-Moreno A, Spielmann N, Wurst W, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Meissner A, Engelhardt S, Rinn JL, Andergassen D. Hasenbein TP, et al. Among authors: wurst w. Nat Commun. 2024 Dec 5;15(1):10631. doi: 10.1038/s41467-024-54673-5. Nat Commun. 2024. PMID: 39638999 Free PMC article.
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Among authors: wurst w. Immunity. 2024 Dec 4:S1074-7613(24)00539-9. doi: 10.1016/j.immuni.2024.11.024. Online ahead of print. Immunity. 2024. PMID: 39637851 No abstract available.
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Among authors: wurst w. Immunity. 2024 Nov 12;57(11):2651-2668.e12. doi: 10.1016/j.immuni.2024.09.014. Epub 2024 Oct 16. Immunity. 2024. PMID: 39419029 Free article.
Correction to "The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression".
Xu M, Ito-Kureha T, Kang HS, Chernev A, Raj T, Hoefig KP, Hohn C, Giesert F, Wang Y, Pan W, Ziętara N, Straub T, Feederle R, Daniel C, Adler B, König J, Feske S, Tsokos GC, Wurst W, Urlaub H, Sattler M, Kisielow J, Wulczyn FG, Łyszkiewicz M, Heissmeyer V. Xu M, et al. Among authors: wurst w. Nat Commun. 2024 Aug 5;15(1):6632. doi: 10.1038/s41467-024-50610-8. Nat Commun. 2024. PMID: 39103338 Free PMC article. No abstract available.
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation.
Wang M, Flaswinkel H, Joshi A, Napoli M, Masgrau-Alsina S, Kamper JM, Henne A, Heinz A, Berouti M, Schmacke NA, Hiller K, Kremmer E, Wefers B, Wurst W, Sperandio M, Ruland J, Fröhlich T, Hornung V. Wang M, et al. Among authors: wurst w. Nat Commun. 2024 Jul 31;15(1):6438. doi: 10.1038/s41467-024-50104-7. Nat Commun. 2024. PMID: 39085210 Free PMC article.
PARK7/DJ-1 deficiency impairs microglial activation in response to LPS-induced inflammation.
Lind-Holm Mogensen F, Sousa C, Ameli C, Badanjak K, Pereira SL, Muller A, Kaoma T, Coowar D, Scafidi A, Poovathingal SK, Tziortziou M, Antony PMA, Nicot N, Ginolhac A, Vogt Weisenhorn DM, Wurst W, Poli A, Nazarov PV, Skupin A, Grünewald A, Michelucci A. Lind-Holm Mogensen F, et al. Among authors: wurst w. J Neuroinflammation. 2024 Jul 16;21(1):174. doi: 10.1186/s12974-024-03164-x. J Neuroinflammation. 2024. PMID: 39014482 Free PMC article.
Rational correction of pathogenic conformational defects in HTRA1.
Beaufort N, Ingendahl L, Merdanovic M, Schmidt A, Podlesainski D, Richter T, Neumann T, Kuszner M, Vetter IR, Stege P, Burston SG, Filipovic A, Ruiz-Blanco YB, Bravo-Rodriguez K, Mieres-Perez J, Beuck C, Uebel S, Zobawa M, Schillinger J, Malik R, Todorov-Völgyi K, Rey J, Roberti A, Hagemeier B, Wefers B, Müller SA, Wurst W, Sanchez-Garcia E, Zimmermann A, Hu XY, Clausen T, Huber R, Lichtenthaler SF, Schmuck C, Giese M, Kaiser M, Ehrmann M, Dichgans M. Beaufort N, et al. Among authors: wurst w. Nat Commun. 2024 Jul 16;15(1):5944. doi: 10.1038/s41467-024-49982-8. Nat Commun. 2024. PMID: 39013852 Free PMC article.
551 results