Datta-Mannan A - Search Results

1

Evaluation of Pharmacokinetics of Lebrikizumab in Healthy Individuals After Subcutaneous Administration Using a Prefilled Syringe or Autoinjector in a Phase 1 Randomized Study.

Datta-Mannan A, Moser B, Xu W, Jackson K, Witcher J, Armstrong AW, Blauvelt A, Lio PA. Datta-Mannan A, et al. Clin Ther. 2024 Dec 4:S0149-2918(24)00323-0. doi: 10.1016/j.clinthera.2024.10.016. Online ahead of print. Clin Ther. 2024. PMID: 39638723 Free article.

2

Safety, Tolerability, and Pharmacokinetics of an Oral Small Molecule Inhibitor of IL-17A (LY3509754): A Phase I Randomized Placebo-Controlled Study.

Datta-Mannan A, Regev A, Coutant DE, Dropsey AJ, Foster J, Jones S, Poorbaugh J, Schmitz C, Wang E, Woodman ME. Datta-Mannan A, et al. Clin Pharmacol Ther. 2024 May;115(5):1152-1161. doi: 10.1002/cpt.3185. Epub 2024 Jan 31. Clin Pharmacol Ther. 2024. PMID: 38294091 Clinical Trial.

3

Identification of a Safe and Tolerable Carbamazepine Dosing Paradigm that Facilitates Effective Evaluation of CYP3A4 Induction.

Datta-Mannan A, Shanks E, Yuen E, Jin Y, Rehmel J, Hall SD. Datta-Mannan A, et al. Clin Pharmacol Ther. 2024 Oct;116(4):1034-1041. doi: 10.1002/cpt.3332. Epub 2024 Jun 12. Clin Pharmacol Ther. 2024. PMID: 38864600 Clinical Trial.

4

Impact of COVID-19 on the Conduct and Design of Clinical Trials: IQ Consortium Perspective.

Mohamed MF, Girish S, Humeniuk R, Nuthalapati S, Desai A, Datta-Mannan A, Gheyas F, Kanodia J, Cheeti S, Zhu T. Mohamed MF, et al. Among authors: datta mannan a. Clin Pharmacol Ther. 2024 Jul;116(1):26-29. doi: 10.1002/cpt.3242. Epub 2024 Mar 27. Clin Pharmacol Ther. 2024. PMID: 38536001 No abstract available.

5

Monoclonal Antibody Pharmacokinetics in Cynomolgus Monkeys Following Subcutaneous Administration: Physiologically Based Model Predictions from Physiochemical Properties.

Hu S, Datta-Mannan A, D'Argenio DZ. Hu S, et al. Among authors: datta mannan a. AAPS J. 2022 Dec 1;25(1):5. doi: 10.1208/s12248-022-00772-4. AAPS J. 2022. PMID: 36456779

6

Generation and activity of a humanized monoclonal antibody that selectively neutralizes the epidermal growth factor receptor ligands transforming growth factor-α and epiregulin.

Beidler CB, Petrovan RJ, Conner EM, Boyles JS, Yang DD, Harlan SM, Chu S, Ellis B, Datta-Mannan A, Johnson RL, Stauber A, Witcher DR, Breyer MD, Heuer JG. Beidler CB, et al. J Pharmacol Exp Ther. 2014 May;349(2):330-43. doi: 10.1124/jpet.113.210765. Epub 2014 Feb 11. J Pharmacol Exp Ther. 2014. PMID: 24518034

7

Real-World Evidence Application in Translational Medicine: Making Use of Prescription Claims to Inform Drug-Drug Interactions of a New Psoriasis Treatment.

Choong CK, Rehmel J, Datta-Mannan A. Choong CK, et al. Among authors: datta mannan a. J Clin Pharmacol. 2024 Aug 28;65(1):66-73. doi: 10.1002/jcph.6118. Online ahead of print. J Clin Pharmacol. 2024. PMID: 39196280 Free PMC article.

8

An engineered human follistatin variant: insights into the pharmacokinetic and pharmocodynamic relationships of a novel molecule with broad therapeutic potential.

Datta-Mannan A, Yaden B, Krishnan V, Jones BE, Croy JE. Datta-Mannan A, et al. J Pharmacol Exp Ther. 2013 Mar;344(3):616-23. doi: 10.1124/jpet.112.201491. Epub 2012 Dec 17. J Pharmacol Exp Ther. 2013. PMID: 23249626

9

Physiologically Based Modeling to Predict Monoclonal Antibody Pharmacokinetics in Humans from in vitro Physiochemical Properties.

Hu S, Datta-Mannan A, D'Argenio DZ. Hu S, et al. MAbs. 2022 Jan-Dec;14(1):2056944. doi: 10.1080/19420862.2022.2056944. MAbs. 2022. PMID: 35491902 Free PMC article.

10

Mechanisms Influencing the Pharmacokinetics and Disposition of Monoclonal Antibodies and Peptides.

Datta-Mannan A. Datta-Mannan A. Drug Metab Dispos. 2019 Oct;47(10):1100-1110. doi: 10.1124/dmd.119.086488. Epub 2019 May 1. Drug Metab Dispos. 2019. PMID: 31043438 Review.

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