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Page 1
The inflammasome adaptor protein ASC promotes amyloid deposition in cryopyrin-associated periodic syndromes.
Alarcón-Vila C, Hurtado-Navarro L, Mateo SV, Peñín-Franch A, Martínez CM, Molina-López C, Baños MC, Gómez AI, Gómez-Román J, Baroja-Mazo A, Arostegui JI, Palmou-Fontana N, Martínez-García JJ, Pelegrin P. Alarcón-Vila C, et al. Among authors: hurtado navarro l. EMBO Mol Med. 2024 Dec 5. doi: 10.1038/s44321-024-00176-1. Online ahead of print. EMBO Mol Med. 2024. PMID: 39639164 Free article. No abstract available.
Ornithine lipid is a partial TLR4 agonist and NLRP3 activator.
Pizzuto M, Hurtado-Navarro L, Molina-Lopez C, Soubhye J, Gelbcke M, Rodriguez-Lopez S, Ruysschaert JM, Schroder K, Pelegrin P. Pizzuto M, et al. Among authors: hurtado navarro l. Cell Rep. 2024 Oct 22;43(10):114788. doi: 10.1016/j.celrep.2024.114788. Epub 2024 Sep 26. Cell Rep. 2024. PMID: 39340778 Free article.
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production.
Molina-López C, Hurtado-Navarro L, García CJ, Angosto-Bazarra D, Vallejo F, Tapia-Abellán A, Marques-Soares JR, Vargas C, Bujan-Rivas S, Tomás-Barberán FA, Arostegui JI, Pelegrin P. Molina-López C, et al. Among authors: hurtado navarro l. Nat Commun. 2024 Feb 6;15(1):1096. doi: 10.1038/s41467-024-44990-0. Nat Commun. 2024. PMID: 38321014 Free PMC article.
NLRP3 inflammasome activation and symptom burden in KRAS-mutated CMML patients is reverted by IL-1 blocking therapy.
Hurtado-Navarro L, Cuenca-Zamora EJ, Zamora L, Bellosillo B, Such E, Soler-Espejo E, Martínez-Banaclocha H, Hernández-Rivas JM, Marco-Ayala J, Martínez-Alarcón L, Linares-Latorre L, García-Ávila S, Amat-Martínez P, González T, Arnan M, Pomares-Marín H, Carreño-Tarragona G, Chen-Liang TH, Herranz MT, García-Palenciano C, Morales ML, Jerez A, Lozano ML, Teruel-Montoya R, Pelegrín P, Ferrer-Marín F. Hurtado-Navarro L, et al. Cell Rep Med. 2023 Dec 19;4(12):101329. doi: 10.1016/j.xcrm.2023.101329. Cell Rep Med. 2023. PMID: 38118408 Free PMC article.
Increased NLRP3 Inflammasome Activation and Pyroptosis in Patients With Multiple Sclerosis With Fingolimod Treatment Failure.
Malhotra S, Hurtado-Navarro L, Pappolla A, Villar LMM, Río J, Montalban X, Pelegrin P, Comabella M. Malhotra S, et al. Among authors: hurtado navarro l. Neurol Neuroimmunol Neuroinflamm. 2023 Mar 27;10(3):e200100. doi: 10.1212/NXI.0000000000200100. Print 2023 May. Neurol Neuroimmunol Neuroinflamm. 2023. PMID: 36973075 Free PMC article.
Early-onset recurrent panniculitis as a phenotype of NLRC4-associated autoinflammatory syndrome: Characterization of pathogenicity of the p.Ser445Pro NLRC4 variant.
Gil-Lianes J, Gariup G, Iranzo-Fernández P, Mensa-Vilaró A, Peñín-Franch A, Hurtado-Navarro L, Pelegrin P, Aróstegui JI. Gil-Lianes J, et al. Among authors: hurtado navarro l. Australas J Dermatol. 2023 May;64(2):260-267. doi: 10.1111/ajd.14005. Epub 2023 Feb 16. Australas J Dermatol. 2023. PMID: 36797819
15 results