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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors.
Clavaín L, Fernández-Pisonero I, Movilla N, Lorenzo-Martín LF, Nieto B, Abad A, García-Navas R, Llorente-González C, Sánchez-Martín M, Vicente-Manzanares M, Santos E, Alarcón B, García-Aznar JM, Dosil M, Bustelo XR. Clavaín L, et al. Among authors: dosil m. Oncogene. 2023 Jan;42(5):389-405. doi: 10.1038/s41388-022-02563-9. Epub 2022 Dec 7. Oncogene. 2023. PMID: 36476833 Free PMC article.
Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model.
Robles-Valero J, Fernández-Nevado L, Cuadrado M, Lorenzo-Martín LF, Fernández-Pisonero I, Abad A, Redín E, Montuenga L, Martín-Zanca D, Bigas A, Mallo M, Dosil M, Bustelo XR. Robles-Valero J, et al. Among authors: dosil m. Mol Oncol. 2022 Oct;16(19):3533-3553. doi: 10.1002/1878-0261.13295. Epub 2022 Aug 30. Mol Oncol. 2022. PMID: 35895495 Free PMC article.
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors.
Fernández-Pisonero I, Clavaín L, Robles-Valero J, Lorenzo-Martín LF, Caloto R, Nieto B, García-Macías C, Oeste CL, Sánchez-Martín M, Abad A, Hortal A, Caballero D, González M, Dosil M, Alarcón B, Bustelo XR. Fernández-Pisonero I, et al. Among authors: dosil m. Cell Rep. 2022 Mar 15;38(11):110522. doi: 10.1016/j.celrep.2022.110522. Cell Rep. 2022. PMID: 35294890 Free article.
80 results