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Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.
Gitelman SE, Bundy BN, Ferrannini E, Lim N, Blanchfield JL, DiMeglio LA, Felner EI, Gaglia JL, Gottlieb PA, Long SA, Mari A, Mirmira RG, Raskin P, Sanda S, Tsalikian E, Wentworth JM, Willi SM, Krischer JP, Bluestone JA; Gleevec Trial Study Group. Gitelman SE, et al. Among authors: mirmira rg. Lancet Diabetes Endocrinol. 2021 Aug;9(8):502-514. doi: 10.1016/S2213-8587(21)00139-X. Epub 2021 Jun 29. Lancet Diabetes Endocrinol. 2021. PMID: 34214479 Free PMC article. Clinical Trial.
A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes.
Syed F, Singhal D, Raedschelders K, Krishnan P, Bone RN, McLaughlin MR, Van Eyk JE, Mirmira RG, Yang ML, Mamula MJ, Wu H, Liu X, Evans-Molina C. Syed F, et al. Among authors: mirmira rg. EBioMedicine. 2023 Jan;87:104379. doi: 10.1016/j.ebiom.2022.104379. Epub 2022 Dec 1. EBioMedicine. 2023. PMID: 36463755 Free PMC article.
Protection of β cells against pro-inflammatory cytokine stress by the GDF15-ERBB2 signaling.
Sarkar S, Syed F, Webb-Robertson BJ, Melchior JT, Chang G, Gritsenko M, Wang YT, Tsai CF, Liu J, Yi X, Cui Y, Eizirik DL, Metz TO, Rewers M, Evans-Molina C, Mirmira RG, Nakayasu ES. Sarkar S, et al. Among authors: mirmira rg. medRxiv [Preprint]. 2023 Nov 27:2023.11.27.23298904. doi: 10.1101/2023.11.27.23298904. medRxiv. 2023. PMID: 38076918 Free PMC article. Preprint.
Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis.
Sarkar S, Deiter C, Kyle JE, Guney MA, Sarbaugh D, Yin R, Li X, Cui Y, Ramos-Rodriguez M, Nicora CD, Syed F, Juan-Mateu J, Muralidharan C, Pasquali L, Evans-Molina C, Eizirik DL, Webb-Robertson BM, Burnum-Johnson K, Orr G, Laskin J, Metz TO, Mirmira RG, Sussel L, Ansong C, Nakayasu ES. Sarkar S, et al. Among authors: mirmira rg. Cell Commun Signal. 2024 Feb 21;22(1):141. doi: 10.1186/s12964-023-01437-1. Cell Commun Signal. 2024. PMID: 38383396 Free PMC article.
Inhibition of the eukaryotic initiation factor-2α kinase PERK decreases risk of autoimmune diabetes in mice.
Muralidharan C, Huang F, Enriquez JR, Wang JE, Nelson JB, Nargis T, May SC, Chakraborty A, Figatner KT, Navitskaya S, Anderson CM, Calvo V, Surguladze D, Mulvihill MJ, Yi X, Sarkar S, Oakes SA, Webb-Robertson BM, Sims EK, Staschke KA, Eizirik DL, Nakayasu ES, Stokes ME, Tersey SA, Mirmira RG. Muralidharan C, et al. Among authors: mirmira rg. J Clin Invest. 2024 Jun 18;134(16):e176136. doi: 10.1172/JCI176136. J Clin Invest. 2024. PMID: 38889047 Free PMC article.
202 results