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Epitope-focused immunogens targeting the hepatitis C virus glycoproteins induce broadly neutralizing antibodies.
Nagarathinam K, Scheck A, Labuhn M, Ströh LJ, Herold E, Veselkova B, Tune S, Cramer JT, Rosset S, Vollers SS, Bankwitz D, Ballmaier M, Böning H, Roth E, Khera T, Ahsendorf-Abidi HP, Dittrich-Breiholz O, Obleser J, Nassal M, Jäck HM, Pietschmann T, Correia BE, Krey T. Nagarathinam K, et al. Among authors: jack hm. Sci Adv. 2024 Dec 6;10(49):eado2600. doi: 10.1126/sciadv.ado2600. Epub 2024 Dec 6. Sci Adv. 2024. PMID: 39642219 Free PMC article.
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model.
Peter AS, Roth E, Schulz SR, Fraedrich K, Steinmetz T, Damm D, Hauke M, Richel E, Mueller-Schmucker S, Habenicht K, Eberlein V, Issmail L, Uhlig N, Dolles S, Grüner E, Peterhoff D, Ciesek S, Hoffmann M, Pöhlmann S, McKay PF, Shattock RJ, Wölfel R, Socher E, Wagner R, Eichler J, Sticht H, Schuh W, Neipel F, Ensser A, Mielenz D, Tenbusch M, Winkler TH, Grunwald T, Überla K, Jäck HM. Peter AS, et al. Among authors: jack hm. Eur J Immunol. 2022 May;52(5):770-783. doi: 10.1002/eji.202149374. Epub 2021 Sep 13. Eur J Immunol. 2022. PMID: 34355795 Free PMC article.
A surrogate cell-based SARS-CoV-2 spike blocking assay.
Schuh W, Baus L, Steinmetz T, Schulz SR, Weckwerth L, Roth E, Hauke M, Krause S, Morhart P, Rauh M, Hoffmann M, Vesper N, Reth M, Schneider H, Jäck HM, Mielenz D. Schuh W, et al. Among authors: jack hm. Eur J Immunol. 2021 Nov;51(11):2665-2676. doi: 10.1002/eji.202149302. Epub 2021 Sep 28. Eur J Immunol. 2021. PMID: 34547822 Free PMC article.
Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.
Burnett DL, Jackson KJL, Langley DB, Aggrawal A, Stella AO, Johansen MD, Balachandran H, Lenthall H, Rouet R, Walker G, Saunders BM, Singh M, Li H, Henry JY, Jackson J, Stewart AG, Witthauer F, Spence MA, Hansbro NG, Jackson C, Schofield P, Milthorpe C, Martinello M, Schulz SR, Roth E, Kelleher A, Emery S, Britton WJ, Rawlinson WD, Karl R, Schäfer S, Winkler TH, Brink R, Bull RA, Hansbro PM, Jäck HM, Turville S, Christ D, Goodnow CC. Burnett DL, et al. Among authors: jack hm. Immunity. 2021 Dec 14;54(12):2908-2921.e6. doi: 10.1016/j.immuni.2021.10.019. Epub 2021 Oct 29. Immunity. 2021. PMID: 34788600 Free PMC article.
Towards the generation of B-cell receptor retrogenic mice.
Freitag J, Heink S, Roth E, Wittmann J, Jäck HM, Kamradt T. Freitag J, et al. Among authors: jack hm. PLoS One. 2014 Oct 8;9(10):e109199. doi: 10.1371/journal.pone.0109199. eCollection 2014. PLoS One. 2014. PMID: 25296340 Free PMC article.
168 results