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Self-organization of the hematopoietic vascular niche and emergent innate immunity on a chip.
Georgescu A, Oved JH, Galarraga JH, Cantrell T, Mehta S, Dulmovits BM, Olson TS, Fattahi P, Wang A, Candarlioglu PL, Muvaffak A, Kim MM, Aydin SA, Seo J, Diffenderfer ES, Lynch A, Worthen GS, Huh DD. Georgescu A, et al. Among authors: diffenderfer es. Cell Stem Cell. 2024 Dec 5;31(12):1847-1864.e6. doi: 10.1016/j.stem.2024.11.003. Cell Stem Cell. 2024. PMID: 39642865
Comparison of FLASH Proton Entrance and the Spread-Out Bragg Peak Dose Regions in the Sparing of Mouse Intestinal Crypts and in a Pancreatic Tumor Model.
Kim MM, Verginadis II, Goia D, Haertter A, Shoniyozov K, Zou W, Maity A, Busch TM, Metz JM, Cengel KA, Dong L, Koumenis C, Diffenderfer ES. Kim MM, et al. Among authors: diffenderfer es. Cancers (Basel). 2021 Aug 23;13(16):4244. doi: 10.3390/cancers13164244. Cancers (Basel). 2021. PMID: 34439398 Free PMC article.
Design, Implementation, and in Vivo Validation of a Novel Proton FLASH Radiation Therapy System.
Diffenderfer ES, Verginadis II, Kim MM, Shoniyozov K, Velalopoulou A, Goia D, Putt M, Hagan S, Avery S, Teo K, Zou W, Lin A, Swisher-McClure S, Koch C, Kennedy AR, Minn A, Maity A, Busch TM, Dong L, Koumenis C, Metz J, Cengel KA. Diffenderfer ES, et al. Int J Radiat Oncol Biol Phys. 2020 Feb 1;106(2):440-448. doi: 10.1016/j.ijrobp.2019.10.049. Int J Radiat Oncol Biol Phys. 2020. PMID: 31928642 Free PMC article.
FLASH Proton Radiation Therapy Mitigates Inflammatory and Fibrotic Pathways and Preserves Cardiac Function in a Preclinical Mouse Model of Radiation-Induced Heart Disease.
Kim K, Kim MM, Skoufos G, Diffenderfer ES, Motlagh SAO, Kokkorakis M, Koliaki I, Morcos G, Shoniyozov K, Griffin J, Hatzigeorgiou AG, Metz JM, Lin A, Feigenberg SJ, Cengel KA, Ky B, Koumenis C, Verginadis II. Kim K, et al. Among authors: diffenderfer es. Int J Radiat Oncol Biol Phys. 2024 Jul 15;119(4):1234-1247. doi: 10.1016/j.ijrobp.2024.01.224. Epub 2024 Feb 15. Int J Radiat Oncol Biol Phys. 2024. PMID: 38364948 Free PMC article.
Proton radiation boosts the efficacy of mesothelin-targeting chimeric antigen receptor T cell therapy in pancreatic cancer.
Amit U, Uslu U, Verginadis II, Kim MM, Motlagh SAO, Diffenderfer ES, Assenmacher CA, Bicher S, Atoche SJ, Ben-Josef E, Young RM, June CH, Koumenis C. Amit U, et al. Among authors: diffenderfer es. Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2403002121. doi: 10.1073/pnas.2403002121. Epub 2024 Jul 24. Proc Natl Acad Sci U S A. 2024. PMID: 39047033 Free PMC article.
Characterization of a high-resolution 2D transmission ion chamber for independent validation of proton pencil beam scanning of conventional and FLASH dose delivery.
Zou W, Diffenderfer ES, Ota K, Boisseau P, Kim MM, Cai Y, Avery SM, Carlson DJ, Wiersma RD, Lin A, Koumenis C, Cengel KA, Metz JM, Dong L, Teo BK. Zou W, et al. Among authors: diffenderfer es. Med Phys. 2021 Jul;48(7):3948-3957. doi: 10.1002/mp.14882. Epub 2021 Jun 3. Med Phys. 2021. PMID: 33843065
Current delivery limitations of proton PBS for FLASH.
Zou W, Diffenderfer ES, Cengel KA, Kim MM, Avery S, Konzer J, Cai Y, Boisseu P, Ota K, Yin L, Wiersma R, Carlson DJ, Fan Y, Busch TM, Koumenis C, Lin A, Metz JM, Teo BK, Dong L. Zou W, et al. Among authors: diffenderfer es. Radiother Oncol. 2021 Feb;155:212-218. doi: 10.1016/j.radonc.2020.11.002. Epub 2020 Nov 11. Radiother Oncol. 2021. PMID: 33186682
39 results