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A genome-wide association meta-analysis links hidradenitis suppurativa to common and rare sequence variants causing disruption of the Notch and Wnt/β-catenin signaling pathways.
Kjærsgaard Andersen R, Stefansdottir L, Riis PT, Halldorsson G, Ferkingstad E, Oddsson A, Walters B, Olafsdottir TA, Rutsdottir G, Zachariae C, Thomsen SF, Brodersen T, Dinh KM, Knowlton KU, Knight S, Nadauld LD, Banasik K, Brunak S, Hansen TF, Hjalgrim H, Sørensen E, Mikkelsen C, Ullum H, Nyegaard M, Bruun MT, Erikstrup C, Ostrowski SR, Eidsmo L, Saunte DML, Sigurgeirsson B, Orvar KB, Saemundsdottir J, Melsted P, Norddahl GL, Sulem P, Stefansson H, Holm H, Gudbjartsson D, Thorleifsson G, Jonsdottir I, Pedersen OBV, Jemec GBE, Stefansson K. Kjærsgaard Andersen R, et al. Among authors: eidsmo l. J Am Acad Dermatol. 2024 Dec 5:S0190-9622(24)03292-4. doi: 10.1016/j.jaad.2024.11.050. Online ahead of print. J Am Acad Dermatol. 2024. PMID: 39645042 Free article.
Initial steps towards developing a predictive algorithm of disease progression for hidradenitis suppurativa (HS): results from a Cox proportional hazard regression analysis on disease progression among a cohort of 335 Danish patients with HS.
Kjærsgaard Andersen R, Pedersen O, Eidsmo L, Jemec G, Saunte D. Kjærsgaard Andersen R, et al. Among authors: eidsmo l. Br J Dermatol. 2024 May 17;190(6):904-914. doi: 10.1093/bjd/ljad530. Br J Dermatol. 2024. PMID: 38169316
Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory.
Emmanuel T, Ignatov B, Bertelsen T, Litman T, Nielsen MM, Brent MB, Touborg T, Rønsholdt AB, Petersen A, Boye M, Kaaber I, Sortebech D, Lybæk D, Steiniche T, Bregnhøj A, Eidsmo L, Iversen L, Johansen C. Emmanuel T, et al. Among authors: eidsmo l. Int J Mol Sci. 2024 May 31;25(11):6086. doi: 10.3390/ijms25116086. Int J Mol Sci. 2024. PMID: 38892277 Free PMC article.
Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation.
Zwijnenburg AJ, Pokharel J, Varnaitė R, Zheng W, Hoffer E, Shryki I, Comet NR, Ehrström M, Gredmark-Russ S, Eidsmo L, Gerlach C. Zwijnenburg AJ, et al. Among authors: eidsmo l. Immunity. 2023 Aug 8;56(8):1955-1974.e10. doi: 10.1016/j.immuni.2023.06.025. Epub 2023 Jul 24. Immunity. 2023. PMID: 37490909 Free article.
Human skin-resident CD8+ T cells require RUNX2 and RUNX3 for induction of cytotoxicity and expression of the integrin CD49a.
Zitti B, Hoffer E, Zheng W, Pandey RV, Schlums H, Perinetti Casoni G, Fusi I, Nguyen L, Kärner J, Kokkinou E, Carrasco A, Gahm J, Ehrström M, Happaniemi S, Keita ÅV, Hedin CRH, Mjösberg J, Eidsmo L, Bryceson YT. Zitti B, et al. Among authors: eidsmo l. Immunity. 2023 Jun 13;56(6):1285-1302.e7. doi: 10.1016/j.immuni.2023.05.003. Epub 2023 Jun 2. Immunity. 2023. PMID: 37269830 Free article.
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