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898 results

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Page 1
Targeted Proteomic Biomarker Profiling Using NULISA in a cohort enriched with risk for Alzheimer's Disease and Related Dementias.
Reyes RER, Wilson RE, Langhough RE, Studer RL, Jonaitis EM, Oomens JE, Planalp EM, Bendlin BB, Chin NA, Asthana S, Zetterberg H, Johnson SC. Reyes RER, et al. Among authors: asthana s. medRxiv [Preprint]. 2024 Nov 29:2024.11.28.24318162. doi: 10.1101/2024.11.28.24318162. medRxiv. 2024. PMID: 39649596 Free PMC article. Preprint.
Gut Microbiome Compositional and Functional Features Associate with Alzheimer's Disease Pathology.
Kang JW, Khatib LA, Heston MB, Dilmore AH, Labus JS, Deming Y, Schimmel L, Blach C, McDonald D, Gonzalez A, Bryant M, Sanders K, Schwartz A, Ulland TK, Johnson SC, Asthana S, Carlsson CM, Chin NA, Blennow K, Zetterberg H, Rey FE; Alzheimer Gut Microbiome Project Consortium; Kaddurah-Daouk R, Knight R, Bendlin BB. Kang JW, et al. Among authors: asthana s. medRxiv [Preprint]. 2024 Sep 5:2024.09.04.24313004. doi: 10.1101/2024.09.04.24313004. medRxiv. 2024. PMID: 39281749 Free PMC article. Preprint.
Prevalence and Clinical Implications of a β-Amyloid-Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease.
Erickson P, Simrén J, Brum WS, Ennis GE, Kollmorgen G, Suridjan I, Langhough R, Jonaitis EM, Van Hulle CA, Betthauser TJ, Carlsson CM, Asthana S, Ashton NJ, Johnson SC, Shaw LM, Blennow K, Andreasson U, Bendlin BB, Zetterberg H; ADNI Cohort. Erickson P, et al. Among authors: asthana s. JAMA Neurol. 2023 Jul 31;80(9):969-79. doi: 10.1001/jamaneurol.2023.2338. Online ahead of print. JAMA Neurol. 2023. PMID: 37523162 Free PMC article.
Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabow… See abstract for full author list ➔ Rajabli F, et al. Among authors: asthana s. medRxiv [Preprint]. 2023 Jul 8:2023.07.06.23292311. doi: 10.1101/2023.07.06.23292311. medRxiv. 2023. PMID: 37461624 Free PMC article. Preprint.
Older adults at greater risk for Alzheimer's disease show stronger associations between sleep apnea severity and verbal memory.
Lui K, Dave A, Sprecher K, Chappel-Farley M, Riedner B, Heston M, Taylor C, Carlsson C, Okonkwo O, Asthana S, Johnson S, Bendlin B, Mander B, Benca R. Lui K, et al. Among authors: asthana s. Res Sq [Preprint]. 2023 Dec 2:rs.3.rs-3683218. doi: 10.21203/rs.3.rs-3683218/v1. Res Sq. 2023. Update in: Alzheimers Res Ther. 2024 May 9;16(1):102. doi: 10.1186/s13195-024-01446-3 PMID: 38076899 Free PMC article. Updated. Preprint.
Whole-body modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer's disease.
Martinelli F, Heinken A, Henning AK, Wörheide MA, Hensen T, González A, Arnold M, Asthana S, Budde K, Engelman CD, Estaki M, Grabe HJ, Heston M, Johnson S, Kastenmüller G, Martino C, McDonald D, Rey F, Kilimann I, Peters O, Wang X, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Glanz W, Buerger K, Janowitz D, Laske C, Munk MH, Spottke A, Roy N, Nauck M, Teipel S, Knight R, Kaddurah-Daouk R, Bendlin BB, Hertel J, Thiele I. Martinelli F, et al. Among authors: asthana s. Res Sq [Preprint]. 2023 Sep 6:rs.3.rs-3306891. doi: 10.21203/rs.3.rs-3306891/v1. Res Sq. 2023. Update in: Sci Rep. 2024 Mar 13;14(1):6095. doi: 10.1038/s41598-024-55960-3 PMID: 37720019 Free PMC article. Updated. Preprint.
Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.
Bateman RJ, Smith J, Donohue MC, Delmar P, Abbas R, Salloway S, Wojtowicz J, Blennow K, Bittner T, Black SE, Klein G, Boada M, Grimmer T, Tamaoka A, Perry RJ, Turner RS, Watson D, Woodward M, Thanasopoulou A, Lane C, Baudler M, Fox NC, Cummings JL, Fontoura P, Doody RS; GRADUATE I and II Investigators and the Gantenerumab Study Group. Bateman RJ, et al. N Engl J Med. 2023 Nov 16;389(20):1862-1876. doi: 10.1056/NEJMoa2304430. N Engl J Med. 2023. PMID: 37966285 Free PMC article. Clinical Trial.
898 results