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Page 1
A STAG2-PAXIP1/PAGR1 axis suppresses lung tumorigenesis.
Ashkin EL, Tang YJ, Xu H, Hung KL, Belk JA, Cai H, Lopez SS, Dolcen DN, Hebert JD, Li R, Ruiz PA, Keal T, Andrejka L, Chang HY, Petrov DA, Dixon JR, Xu Z, Winslow MM. Ashkin EL, et al. Among authors: belk ja. J Exp Med. 2025 Jan 6;222(1):e20240765. doi: 10.1084/jem.20240765. Epub 2024 Dec 9. J Exp Med. 2025. PMID: 39652422
ecDNA hubs drive cooperative intermolecular oncogene expression.
Hung KL, Yost KE, Xie L, Shi Q, Helmsauer K, Luebeck J, Schöpflin R, Lange JT, Chamorro González R, Weiser NE, Chen C, Valieva ME, Wong IT, Wu S, Dehkordi SR, Duffy CV, Kraft K, Tang J, Belk JA, Rose JC, Corces MR, Granja JM, Li R, Rajkumar U, Friedlein J, Bagchi A, Satpathy AT, Tjian R, Mundlos S, Bafna V, Henssen AG, Mischel PS, Liu Z, Chang HY. Hung KL, et al. Among authors: belk ja. Nature. 2021 Dec;600(7890):731-736. doi: 10.1038/s41586-021-04116-8. Epub 2021 Nov 24. Nature. 2021. PMID: 34819668 Free PMC article.
Coordinated inheritance of extrachromosomal DNAs in cancer cells.
Hung KL, Jones MG, Wong IT, Curtis EJ, Lange JT, He BJ, Luebeck J, Schmargon R, Scanu E, Brückner L, Yan X, Li R, Gnanasekar A, Chamorro González R, Belk JA, Liu Z, Melillo B, Bafna V, Dörr JR, Werner B, Huang W, Cravatt BF, Henssen AG, Mischel PS, Chang HY. Hung KL, et al. Among authors: belk ja. Nature. 2024 Nov;635(8037):201-209. doi: 10.1038/s41586-024-07861-8. Epub 2024 Nov 6. Nature. 2024. PMID: 39506152 Free PMC article.
Coordinated inheritance of extrachromosomal DNA species in human cancer cells.
Hung KL, Jones MG, Wong IT, Lange JT, Luebeck J, Scanu E, He BJ, Brückner L, Li R, González RC, Schmargon R, Dörr JR, Belk JA, Bafna V, Werner B, Huang W, Henssen AG, Mischel PS, Chang HY. Hung KL, et al. Among authors: belk ja. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549597. doi: 10.1101/2023.07.18.549597. bioRxiv. 2023. Update in: Nature. 2024 Nov;635(8037):201-209. doi: 10.1038/s41586-024-07861-8 PMID: 37503111 Free PMC article. Updated. Preprint.
Clonal inactivation of TERT impairs stem cell competition.
Hasegawa K, Zhao Y, Garbuzov A, Corces MR, Neuhöfer P, Gillespie VM, Cheung P, Belk JA, Huang YH, Wei Y, Chen L, Chang HY, Artandi SE. Hasegawa K, et al. Among authors: belk ja. Nature. 2024 Aug;632(8023):201-208. doi: 10.1038/s41586-024-07700-w. Epub 2024 Jul 17. Nature. 2024. PMID: 39020172 Free PMC article.
Disparate Pathways for Extrachromosomal DNA Biogenesis and Genomic DNA Repair.
Rose JC, Belk JA, Wong IT, Luebeck J, Horn HT, Daniel B, Jones MG, Yost KE, Hung KL, Kolahi KS, Curtis EJ, Kuo CJ, Bafna V, Mischel PS, Chang HY. Rose JC, et al. Among authors: belk ja. Cancer Discov. 2025 Jan 13;15(1):69-82. doi: 10.1158/2159-8290.CD-23-1117. Cancer Discov. 2025. PMID: 39109936 Free PMC article.
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette JE, Bertozzi CR, Wilen CB, Satpathy AT. Flynn RA, et al. Among authors: belk ja. Cell. 2021 Apr 29;184(9):2394-2411.e16. doi: 10.1016/j.cell.2021.03.012. Epub 2021 Mar 11. Cell. 2021. PMID: 33743211 Free PMC article.
Engineered cell entry links receptor biology with single-cell genomics.
Yu B, Shi Q, Belk JA, Yost KE, Parker KR, Li R, Liu BB, Huang H, Lingwood D, Greenleaf WJ, Davis MM, Satpathy AT, Chang HY. Yu B, et al. Among authors: belk ja. Cell. 2022 Dec 22;185(26):4904-4920.e22. doi: 10.1016/j.cell.2022.11.016. Epub 2022 Dec 13. Cell. 2022. PMID: 36516854 Free PMC article.
Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state.
Daniel B, Belk JA, Meier SL, Chen AY, Sandor K, Czimmerer Z, Varga Z, Bene K, Buquicchio FA, Qi Y, Kitano H, Wheeler JR, Foster DS, Januszyk M, Longaker MT, Chang HY, Satpathy AT. Daniel B, et al. Among authors: belk ja. Mol Cell. 2023 Jan 5;83(1):121-138.e7. doi: 10.1016/j.molcel.2022.11.017. Epub 2022 Dec 14. Mol Cell. 2023. PMID: 36521490 Free PMC article.
Xist ribonucleoproteins promote female sex-biased autoimmunity.
Dou DR, Zhao Y, Belk JA, Zhao Y, Casey KM, Chen DC, Li R, Yu B, Srinivasan S, Abe BT, Kraft K, Hellström C, Sjöberg R, Chang S, Feng A, Goldman DW, Shah AA, Petri M, Chung LS, Fiorentino DF, Lundberg EK, Wutz A, Utz PJ, Chang HY. Dou DR, et al. Among authors: belk ja. Cell. 2024 Feb 1;187(3):733-749.e16. doi: 10.1016/j.cell.2023.12.037. Cell. 2024. PMID: 38306984 Free article.
34 results