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ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.
Fucho R, Martínez L, Baulies A, Torres S, Tarrats N, Fernandez A, Ribas V, Astudillo AM, Balsinde J, Garcia-Rovés P, Elena M, Bergheim I, Lotersztajn S, Trautwein C, Appelqvist H, Paton AW, Paton JC, Czaja MJ, Kaplowitz N, Fernandez-Checa JC, García-Ruiz C. Fucho R, et al. Among authors: torres s. J Hepatol. 2014 Nov;61(5):1126-34. doi: 10.1016/j.jhep.2014.06.009. Epub 2014 Jun 16. J Hepatol. 2014. PMID: 24946279 Free PMC article.
Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity.
Moles A, Torres S, Baulies A, Garcia-Ruiz C, Fernandez-Checa JC. Moles A, et al. Among authors: torres s. Front Pharmacol. 2018 May 15;9:453. doi: 10.3389/fphar.2018.00453. eCollection 2018. Front Pharmacol. 2018. PMID: 29867464 Free PMC article. Review.
Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure.
Torres S, Baulies A, Insausti-Urkia N, Alarcón-Vila C, Fucho R, Solsona-Vilarrasa E, Núñez S, Robles D, Ribas V, Wakefield L, Grompe M, Lucena MI, Andrade RJ, Win S, Aung TA, Kaplowitz N, García-Ruiz C, Fernández-Checa JC. Torres S, et al. Gastroenterology. 2019 Aug;157(2):552-568. doi: 10.1053/j.gastro.2019.04.023. Epub 2019 Apr 25. Gastroenterology. 2019. PMID: 31029706 Free article.
Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation.
Torres S, Solsona-Vilarrasa E, Nuñez S, Matías N, Insausti-Urkia N, Castro F, Casasempere M, Fabriás G, Casas J, Enrich C, Fernández-Checa JC, Garcia-Ruiz C. Torres S, et al. Redox Biol. 2021 Sep;45:102052. doi: 10.1016/j.redox.2021.102052. Epub 2021 Jun 19. Redox Biol. 2021. PMID: 34175669 Free PMC article.
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis.
Torres S, Ortiz C, Bachtler N, Gu W, Grünewald LD, Kraus N, Schierwagen R, Hieber C, Meier C, Tyc O, Joseph Brol M, Uschner FE, Nijmeijer B, Welsch C, Berres ML, Garcia-Ruiz C, Fernandez-Checa JC, Trautwein C, Vogl TJ, Zeuzem S, Trebicka J, Klein S. Torres S, et al. Hepatology. 2023 Apr 1;77(4):1228-1240. doi: 10.1002/hep.32746. Epub 2022 Oct 13. Hepatology. 2023. PMID: 35993369 Free PMC article.
1,249 results