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DNA barcoded peptide-MHC multimers to measure and monitor minor histocompatibility antigen-specific T cells after allogeneic stem cell transplantation.
Fuchs KJ, Göransson M, Kester MGD, Ettienne NW, van de Meent M, de Jong RCM, Koster EAS, Halkes CJM, Scheeren F, Heemskerk MHM, van Balen P, Falkenburg JHF, Hadrup SR, Griffioen M. Fuchs KJ, et al. Among authors: van de meent m. J Immunother Cancer. 2024 Dec 9;12(12):e009564. doi: 10.1136/jitc-2024-009564. J Immunother Cancer. 2024. PMID: 39653555 Free PMC article.
Effective treatment of refractory CMV reactivation after allogeneic stem cell transplantation with in vitro-generated CMV pp65-specific CD8+ T-cell lines.
Meij P, Jedema I, Zandvliet ML, van der Heiden PL, van de Meent M, van Egmond HM, van Liempt E, Hoogstraten C, Kruithof S, Veld S, Marijt EW, von dem Borne PA, Lankester AC, Halkes CJ, Falkenburg JH. Meij P, et al. Among authors: van egmond hm, van der heiden pl, van liempt e, van de meent m. J Immunother. 2012 Oct;35(8):621-8. doi: 10.1097/CJI.0b013e31826e35f6. J Immunother. 2012. PMID: 22996368 Clinical Trial.
WT1-specific TCRs directed against newly identified peptides install antitumor reactivity against acute myeloid leukemia and ovarian carcinoma.
van Amerongen RA, Hagedoorn RS, Remst DFG, Assendelft DC, van der Steen DM, Wouters AK, van de Meent M, Kester MGD, de Ru AH, Griffioen M, van Veelen PA, Falkenburg JHF, Heemskerk MHM. van Amerongen RA, et al. Among authors: de ru ah, van veelen pa, van der steen dm, van de meent m. J Immunother Cancer. 2022 Jun;10(6):e004409. doi: 10.1136/jitc-2021-004409. J Immunother Cancer. 2022. PMID: 35728869 Free PMC article.
Expanding the repertoire reveals recurrent, cryptic, and hematopoietic HLA class I minor histocompatibility antigens.
Fuchs KJ, van de Meent M, Honders MW, Khatri I, Kester MGD, Koster EAS, Koutsoumpli G, de Ru AH, van Bergen CAM, van Veelen PA, 't Hoen PAC, van Balen P, van den Akker EB, Veelken JH, Halkes CJM, Falkenburg JHF, Griffioen M. Fuchs KJ, et al. Among authors: van de meent m. Blood. 2024 May 2;143(18):1856-1872. doi: 10.1182/blood.2023022343. Blood. 2024. PMID: 38427583 Free PMC article.
Successful generation of primary virus-specific and anti-tumor T-cell responses from the naive donor T-cell repertoire is determined by the balance between antigen-specific precursor T cells and regulatory T cells.
Jedema I, van de Meent M, Pots J, Kester MG, van der Beek MT, Falkenburg JH. Jedema I, et al. Among authors: van der beek mt, van de meent m. Haematologica. 2011 Aug;96(8):1204-12. doi: 10.3324/haematol.2010.039099. Epub 2011 May 5. Haematologica. 2011. PMID: 21546501 Free PMC article.
Allogeneic HLA-A*02-restricted WT1-specific T cells from mismatched donors are highly reactive but show off-target promiscuity.
Falkenburg WJ, Melenhorst JJ, van de Meent M, Kester MG, Hombrink P, Heemskerk MH, Hagedoorn RS, Gostick E, Price DA, Falkenburg JH, Barrett AJ, Jedema I. Falkenburg WJ, et al. Among authors: van de meent m. J Immunol. 2011 Sep 1;187(5):2824-33. doi: 10.4049/jimmunol.1100852. Epub 2011 Aug 5. J Immunol. 2011. PMID: 21821799 Free article.
HLA class II upregulation during viral infection leads to HLA-DP-directed graft-versus-host disease after CD4+ donor lymphocyte infusion.
Stevanovic S, van Bergen CA, van Luxemburg-Heijs SA, van der Zouwen B, Jordanova ES, Kruisselbrink AB, van de Meent M, Harskamp JC, Claas FH, Marijt EW, Zwaginga JJ, Halkes CJ, Jedema I, Griffioen M, Falkenburg JH. Stevanovic S, et al. Among authors: van luxemburg heijs sa, van der zouwen b, van de meent m, van bergen ca. Blood. 2013 Sep 12;122(11):1963-73. doi: 10.1182/blood-2012-12-470872. Epub 2013 Jun 18. Blood. 2013. PMID: 23777765 Free article. Clinical Trial.
High Mutation Frequency of the PIGA Gene in T Cells Results in Reconstitution of GPI Anchor-/CD52- T Cells That Can Give Early Immune Protection after Alemtuzumab-Based T Cell-Depleted Allogeneic Stem Cell Transplantation.
Loeff FC, Falkenburg JHF, Hageman L, Huisman W, Veld SAJ, van Egmond HME, van de Meent M, von dem Borne PA, Veelken H, Halkes CJM, Jedema I. Loeff FC, et al. Among authors: van de meent m, van egmond hme. J Immunol. 2018 Mar 15;200(6):2199-2208. doi: 10.4049/jimmunol.1701018. Epub 2018 Feb 2. J Immunol. 2018. PMID: 29427418
37 results