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[18F]SF51, a novel 18F-labeled PET radioligand for translocator protein 18kDa (TSPO) in brain, works well in monkeys but fails in humans.
Yan X, Siméon FG, Liow JS, Morse CL, Jana S, Montero Santamaria JA, Jenkins M, Zoghbi SS, Pike VW, Innis RB, Zanotti-Fregonara P. Yan X, et al. Among authors: simeon fg. J Cereb Blood Flow Metab. 2024 Dec 9:271678X241304924. doi: 10.1177/0271678X241304924. Online ahead of print. J Cereb Blood Flow Metab. 2024. PMID: 39654356 Free PMC article.
Comparison of two PET radioligands, [11C]FPEB and [11C]SP203, for quantification of metabotropic glutamate receptor 5 in human brain.
Lohith TG, Tsujikawa T, Siméon FG, Veronese M, Zoghbi SS, Lyoo CH, Kimura Y, Morse CL, Pike VW, Fujita M, Innis RB. Lohith TG, et al. Among authors: simeon fg. J Cereb Blood Flow Metab. 2017 Jul;37(7):2458-2470. doi: 10.1177/0271678X16668891. Epub 2016 Jan 1. J Cereb Blood Flow Metab. 2017. PMID: 27629098 Free PMC article.
In vivo evaluation of a novel 18F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain.
Yan X, Siméon FG, Liow JS, Morse CL, Montero Santamaria JA, Jenkins M, Manly LS, Van Buskirk M, Zoghbi SS, Pike VW, Innis RB, Zanotti-Fregonara P. Yan X, et al. Among authors: simeon fg. Eur J Nucl Med Mol Imaging. 2023 Aug;50(10):2962-2970. doi: 10.1007/s00259-023-06270-9. Epub 2023 May 30. Eur J Nucl Med Mol Imaging. 2023. PMID: 37249618 Free PMC article.
Radiodefluorination of 3-fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile ([18F]SP203), a radioligand for imaging brain metabotropic glutamate subtype-5 receptors with positron emission tomography, occurs by glutathionylation in rat brain.
Shetty HU, Zoghbi SS, Siméon FG, Liow JS, Brown AK, Kannan P, Innis RB, Pike VW. Shetty HU, et al. Among authors: simeon fg. J Pharmacol Exp Ther. 2008 Dec;327(3):727-35. doi: 10.1124/jpet.108.143347. Epub 2008 Sep 19. J Pharmacol Exp Ther. 2008. PMID: 18806125 Free PMC article.
24 results