Engelhardt B - Search Results

1

Semi-mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine.

Thakre N, Maier C, Zha J, Engelhardt B, Wolff JE, Mensing S. Thakre N, et al. Among authors: engelhardt b. CPT Pharmacometrics Syst Pharmacol. 2024 Dec 9. doi: 10.1002/psp4.13284. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39654391 Free article.

2

Use of Clinical Trial Simulations to Compare the Performance of Different Approaches for Population Analyses of Pediatric Pharmacokinetic Data.

Temrikar Z, Muensterman E, Engelhardt B, Mohamed MF. Temrikar Z, et al. Among authors: engelhardt b. J Clin Pharmacol. 2023 Jul;63(7):859-868. doi: 10.1002/jcph.2236. Epub 2023 May 3. J Clin Pharmacol. 2023. PMID: 36905228

3

Venetoclax in biomarker-selected multiple myeloma patients: Impact of exposure on clinical efficacy and safety.

Badawi M, Coppola S, Eckert D, Gopalakrishnan S, Engelhardt B, Doelger E, Huang W, Dobkowska E, Kumar S, Menon RM, Salem AH. Badawi M, et al. Among authors: engelhardt b. Hematol Oncol. 2024 Jan;42(1):e3222. doi: 10.1002/hon.3222. Epub 2023 Sep 23. Hematol Oncol. 2024. PMID: 37740931 Clinical Trial.

4

Dosing of Venetoclax in Pediatric Patients with Relapsed Acute Myeloid Leukemia: Analysis of Developmental Pharmacokinetics and Exposure-Response Relationships.

Badawi M, Gopalakrishnan S, Engelhardt B, Palenski T, Karol SE, Rubnitz JE, Menon R, Salem AH. Badawi M, et al. Among authors: engelhardt b. Clin Ther. 2024 Oct;46(10):759-767. doi: 10.1016/j.clinthera.2024.09.008. Epub 2024 Oct 5. Clin Ther. 2024. PMID: 39368878 Clinical Trial.

5

Exposure-response relationships of venetoclax in combination with carfilzomib and dexamethasone in relapsed/refractory t(11;14) multiple myeloma patients.

Badawi MA, Engelhardt B, Dobkowska E, Deng R, Kaufman JL, Menon R, Salem AH. Badawi MA, et al. Among authors: engelhardt b. Invest New Drugs. 2024 Dec;42(6):635-643. doi: 10.1007/s10637-024-01471-x. Epub 2024 Oct 10. Invest New Drugs. 2024. PMID: 39388024 Free PMC article. Clinical Trial.

6

Understanding TCR T cell knockout behavior using interpretable machine learning.

Blennemann M, Verma A, Bachl S, Carnevale J, Engelhardt BE. Blennemann M, et al. Among authors: engelhardt be. Pac Symp Biocomput. 2025;30:382-393. Pac Symp Biocomput. 2025. PMID: 39670384 Free article.

7

Cellular behavior analysis from live-cell imaging of TCR T cell-cancer cell interactions.

Verma A, Yu C, Bachl S, Lopez I, Schwartz M, Moen E, Kale N, Ching C, Miller G, Dougherty T, Pao E, Graf W, Ward C, Jena S, Marson A, Carnevale J, Van Valen D, Engelhardt BE. Verma A, et al. Among authors: engelhardt be. bioRxiv [Preprint]. 2024 Nov 21:2024.11.19.624390. doi: 10.1101/2024.11.19.624390. bioRxiv. 2024. PMID: 39605616 Free PMC article. Preprint.

8

Pericytes Enrich the Basement Membrane and Reduce Neutrophil Transmigration in an In Vitro Model of Peripheral Inflammation at the Blood-Brain Barrier.

McCloskey MC, Ahmad SD, Widom LP, Kasap P, Gastfriend BD, Shusta EV, Palecek SP, Engelhardt B, Gaborski TR, Flax J, Waugh RE, McGrath JL. McCloskey MC, et al. Among authors: engelhardt b. Biomater Res. 2024 Oct 3;28:0081. doi: 10.34133/bmr.0081. eCollection 2024. Biomater Res. 2024. PMID: 39363889 Free PMC article.

9

Advances and controversies in meningeal biology.

Betsholtz C, Engelhardt B, Koh GY, McDonald DM, Proulx ST, Siegenthaler J. Betsholtz C, et al. Among authors: engelhardt b. Nat Neurosci. 2024 Nov;27(11):2056-2072. doi: 10.1038/s41593-024-01701-8. Epub 2024 Sep 27. Nat Neurosci. 2024. PMID: 39333784 Review.

10

Answering open questions in biology using spatial genomics and structured methods.

Jena SG, Verma A, Engelhardt BE. Jena SG, et al. Among authors: engelhardt be. BMC Bioinformatics. 2024 Sep 4;25(1):291. doi: 10.1186/s12859-024-05912-5. BMC Bioinformatics. 2024. PMID: 39232666 Free PMC article. Review.

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